Applications of radix salviae miltiorrhizae in prevention or preparation of drugs for treating porcine reproductive respiratory syndrome virus infection

A technology for respiratory syndrome and virus infection, applied in the field of medicine, can solve the problems of difficulty in taking effect of synthetic drugs, difficulty in PRRSV, and few antiviral western medicines, and achieves the effects of scientific and reasonable preparation method, inhibition of infection and strong operability
CN110433198AInactive Publication Date: 2019-11-12武汉百药联科科技有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
武汉百药联科科技有限公司
Publication Date
2019-11-12
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention provides a new purpose of radix salviae miltiorrhizae in the technical field of medicines, and specifically relates to applications of radix salviae miltiorrhizae in the prevention or preparation of drugs for treating porcine reproductive respiratory syndrome virus infection. A radix salviae miltiorrhizae extract product can effectively inhibit the infection of a porcine reproductiverespiratory syndrome virus on a Marc-145 cell within a non-toxic dose range, namely, the inhibition rate of the radix salviae miltiorrhizae extract product on the porcine reproductive respiratory syndrome virus can reach more than 90% when the concentration of the radix salviae miltiorrhizae extract product is 0.004-0.032 mg / mL after being dissolved in dimethyl sulfoxide, and under this concentration, the survival rate of the Marc-145 cell is more than 90%. Thus, the radix salviae miltiorrhizae can be further developed into drugs for treating and preventing the porcine reproductive respiratory syndrome virus.
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Description

technical field

[0001] The invention relates to the technical field of medicine, in particular to the application of salvia miltiorrhiza in the preparation of medicine for treating porcine reproductive and respiratory syndrome virus infection. Background technique

[0002] Porcine reproductive and respiratory syndrome, also known as "pig blue ear disease" and "porcine mystery disease", is a highly contagious infectious disease of pigs caused by porcine reproductive and respiratory syndrome virus (Porcine reproductive respiratory syndrome virus, PRRSV) . Since it was discovered in 1990, the disease has rapidly become one of the most serious viral diseases in the pig industry, seriously restricting the development of the global pig industry.

[0003] Under natural conditions, pigs of different breeds and ages can be infected with PRRSV, but pregnant sows and piglets less than 1 month old are most susceptible to infection, and fattening pigs will also develop the disease after...

Claims

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