Traditional Chinese medicine compound hydrogel for skin wound treating and healing, and preparation method and application thereof

Abstract

The invention discloses traditional Chinese medicine compound hydrogel for skin wound treating and healing. The traditional Chinese medicine compound hydrogel for skin wound treating and healing is prepared from a traditional Chinese medicine composition and a substrate, and is characterized in that the traditional Chinese medicine composition is prepared from the following ingredients in parts byweight: 25 to 35 parts of stir-fried radix scutellariae, 25 to 35 parts of radix codonopsis, 15 to 25 parts of radix angelicae sinensis, 25 to 35 parts of stir-fried bighead atractylodes rhizome, 25to 35 parts of radix paeoniae alba, 25 to 35 parts of poria cocos, 6 to 15 parts of pericarpium citri reticulatae, 10 to 20 parts of frankincense preparata, 10 to 20 parts of myrrh preparata, 15 to 25parts of rhizoma bletillae, 15 to 25 parts of honeysuckle flowers, 15 to 25 parts of rhizoma coptidis and 6 to 15 parts of raw liquorice roots. Compared with the prior art, the traditional Chinese medicine compound hydrogel for skin wound treating and healing has the advantages that the effects of promoting skin wound healing, relieving wound skin tissue pathological conditions of mice, promotingfibroblast chemotaxis and inhibiting inflammation-related transcription factors are achieved; meanwhile, various ingredients are used to achieve synergistic effects; the effects of clearing away heatand toxic materials, eliminating dampness, invigorating qi and blood, nourishing yin, removing stasis and promoting tissue regeneration are achieved; and the efficacies are more.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine compound hydrogel for treating skin wound healing, a preparation method and application thereof. Background technique [0002] The skin is the body's first barrier to defend against external stimuli and damage. Skin damage caused by mechanical trauma will lead to microbial invasion, water and protein loss, endocrine and immune dysfunction, etc., and severe cases can cause death. Treatment of skin trauma Essential to human life and health. At present, we commonly use drugs such as antibiotics, anti-inflammatory drugs, sterols, and fibroblast growth-promoting drugs to treat skin wounds. However, the use of western medicines is easy to cause irritation and allergies to human skin, with many adverse reactions and expensive . Most traditional Chinese medicines are natural ingredients, which have the characteristics of fast wound ...

AI Technical Summary

Problems solved by technology

Of course, there are also Chinese medicine hydrogel formulations used for skin wound healing, but there are few reports. After reviewing the literature, it is found that the ingredients used in the reported Chinese medicine hydrogels are all single Chinese medicine ingredients, and the main function is muscle growth. Therefore, It is necessary to develop a compound hydrogel of multi-component traditional Chinese medicine ingredients to exert better curative effect

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