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Poa annua extract and hypoglycemic activity thereof

An extract and an early-maturing technology, which is applied in the field of bluegrass extract to achieve the effects of improving extraction rate, hypoglycemic effect and strong effect

Inactive Publication Date: 2020-02-18
LIAOCHENG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

"Chinese Materia Medica" records that Poa annua decoction has hypoglycemic effect when taken orally, but its optimal extraction method has not been reported yet. The present invention discloses an extract of Poa annua extract, its extraction method and its use as a hypoglycemic drug

Method used

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  • Poa annua extract and hypoglycemic activity thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Example 1: Extract 1

[0022] The bluegrass is extracted by the following extraction method:

[0023] (1) The bluegrass pretreatment includes: washing the bluegrass with distilled water, leaving it to dry in a dark environment, and crushing it into segments with a length of 1 cm.

[0024] (2) Put the pretreated bluegrass into the extraction tank and add water, the ratio of bluegrass:water is 1:15 by weight.

[0025] (3) The reflux extraction method is used for extraction, the extraction temperature is 80° C. for 24 hours with stirring and reflux extraction, and the condensed water is distilled water at normal temperature.

[0026] (4) extracting liquid and bluegrass residue are separated, and what separation residue adopts is the method for gauze filtration, and the number of gauze layers is 5 layers.

[0027] (5) To concentrate the extract, this concentration uses the vacuum concentration commonly used at present.

[0028] (6) Dry the concentrate by vacuum drying to...

Embodiment 2

[0029] Example 2: Extract 2

[0030] The bluegrass is extracted by the following extraction method:

[0031] (1) The bluegrass pretreatment includes: washing the bluegrass with distilled water, leaving it to dry in a dark environment, and crushing it into segments with a length of 1 cm.

[0032] (2) Put the pretreated bluegrass into the extraction tank and add water, by weight, bluegrass: the ratio of water and alcohol mixed solution is 1: 15, and the volume ratio of water and ethanol in the water and alcohol mixed solution is 75 : 25.

[0033] (3) The reflux extraction method is used for extraction, the extraction temperature is 80°C for reflux extraction, and the condensed water is distilled water at normal temperature.

[0034] (4) extracting liquid and bluegrass residue are separated, and what separation residue adopts is the method for gauze filtration, and the number of gauze layers is 5 layers.

[0035] (5) To concentrate the extract, this concentration uses the vacu...

Embodiment 3

[0037] Example 3: Extract 3

[0038] The bluegrass is extracted by the following extraction method:

[0039] (1) The bluegrass pretreatment includes: washing the bluegrass with distilled water, leaving it to dry in a dark environment, and crushing it into segments with a length of 1 cm.

[0040] (2) Put the pretreated bluegrass into the extraction tank and add water, by weight, bluegrass: the ratio of water and alcohol mixed solution is 1: 15, and the volume ratio of water and ethanol in the water and alcohol mixed solution is 50 : 50.

[0041] (3) The reflux extraction method is used for extraction, the extraction temperature is 80° C. for 24 hours with stirring and reflux extraction, and the condensed water is distilled water at normal temperature.

[0042] (4) extracting liquid and bluegrass residue are separated, and what separation residue adopts is the method for gauze filtration, and the number of gauze layers is 5 layers.

[0043] (5) To concentrate the extract, thi...

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Abstract

The present invention discloses a poa annua extract, an extraction method thereof and a use thereof as a hypoglycemic drug. The method comprises the following steps: pretreating poa annua, putting thepretreated poa annua into an extraction tank, also adding water and alcohol, conducting extraction by adopting a reflux extraction method, separating an extract, conducting concentration and drying,and evaluating hypoglycemic activity of the extract. The provided poa annua extract has a relatively strong hypoglycemic effect and is useful for preparing medicines for preventing or treating diabetes mellitus, metabolic syndromes, related diseases thereof, etc.

Description

technical field [0001] The invention discloses a bluegrass extract, its extraction method and its use as a hypoglycemic drug. The bluegrass extract provided by the invention has a strong hypoglycemic effect, and is useful for preparing medicines for preventing or treating diabetes, metabolic syndrome, and related diseases and the like. Background technique [0002] Bluegrass (scientific name: Poa annua L.) is an annual or winter grass plant belonging to the family Poaceae. Stems erect or inclined, soft, up to 30 cm tall, smooth and glabrous. The leaf sheath is slightly flattened, the leaves are flat or folded in half, the texture is soft, often with transverse veins, the top is acute and boat-shaped, and the edges are slightly rough. Panicle wide ovate, spikelet ovate, with small flowers, green; glume thin, lemma ovoid, apex and margin wide membranous, anther yellow, caryopsis spindle-shaped, flowering in April-May, 6-7 monthly results. [0003] Bluegrass is distributed ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P3/10A61P3/00
CPCA61K36/899A61K2236/15A61K2236/333A61P3/00A61P3/10
Inventor 王学堃范雪静王晓倩赵昌瑞陶世佳张晓泽柳仁民
Owner LIAOCHENG UNIV
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