Application of radix bupleuri euphorbia trigona oyster soup and variations thereof, and radix bupleuri and cassia twig soup in preparing medicines for treating sweating type hand-foot-and-mouth diseases

A technology of bupleurum and keel, applied in drug combination, drug delivery, skin diseases, etc., can solve the problems of missing the treatment window, transmission of changes, etc.

Inactive Publication Date: 2020-03-27
JIUJIANG UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0007] To sum up, in the existing western medicine treatment plan for hand, foot and mouth disease, there is no specific anti-enteroviral drug at present. It is generally recommended to use interferon α spray / atomization or intravenous infusion of ribavirin, and "early use is helpful." Certain curative effect", the effect of medication has great limitations; while the traditional Chinese medicine treatment plan is based on clearing away heat and detoxification as the basic idea, and is mostly used in the stage I rash, but the stage I changes to stage II nerve involvement after only 1-5 days period, a slight delay will miss the treatment window

Method used

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  • Application of radix bupleuri euphorbia trigona oyster soup and variations thereof, and radix bupleuri and cassia twig soup in preparing medicines for treating sweating type hand-foot-and-mouth diseases
  • Application of radix bupleuri euphorbia trigona oyster soup and variations thereof, and radix bupleuri and cassia twig soup in preparing medicines for treating sweating type hand-foot-and-mouth diseases
  • Application of radix bupleuri euphorbia trigona oyster soup and variations thereof, and radix bupleuri and cassia twig soup in preparing medicines for treating sweating type hand-foot-and-mouth diseases

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Effect test

Embodiment Construction

[0079] The following clinical data illustrate the effect of traditional Chinese medicine on hand, foot and mouth disease.

[0080] In order to verify the therapeutic effect of the present invention on sweating patients with hand, foot and mouth disease in phase 1 and phase 2, the research group visited the Department of Traditional Chinese Medicine of Tanghe County Rehabilitation and Youfu Hospital in Nanyang City, Henan Province from March 2017 to December 2018. Inclusion criteria for children with hand, foot and mouth disease were carried out in clinical trials, which are described as follows:

[0081] 1. Diagnostic criteria

[0082] (1) Clinically diagnosed cases

[0083] 1. Incubation period

[0084] Mostly 2-10 days, with an average of 3-5 days.

[0085] 2. Clinical symptoms and signs

[0086] According to the occurrence and development process of the disease, the stages and types of hand, foot and mouth disease are:

[0087] Phase 1 - Rash phase: Mainly manifested a...

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Abstract

The invention belongs to the technical field of traditional Chinese medicines and in particular relates to application of radix bupleuri euphorbia trigona oyster soup and variations thereof, and radixbupleuri and cassia twig soup in treating patients suffering from sweating type hand-foot-and-mouth diseases at a phase 1 and a phase 2. Clinical experiments show that the soup has remarkable advantages in recovery, effect taking and the number of effective people, and differences have statistic differences. Viewing from specific symptoms, experiment groups have statistical significances in advantages in three symptoms of rash distribution situations, food intake reduction and mouth thirsting and lip dryness and have advantages in salivation, expression tireness, dysphoria, skittishness, emesis, tempering, limb shaking and myasthenia without statistical differences.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to the application of Bupleurum plus Longgu Muli Decoction and its modification, and Chaihu Guizhi Decoction in the treatment of patients with sweating type of hand, foot and mouth disease in the first and second stages. Background technique [0002] Hand, foot and mouth disease is an infectious disease caused by enterovirus. It mostly occurs in children under 5 years old. It manifests as mouth pain, anorexia, low-grade fever, small herpes or small ulcers on hands, feet, mouth and other parts. Most children recover by themselves in about a week. , a small number of children can cause myocarditis, pulmonary edema, aseptic meningoencephalitis and other complications. Individual critically ill children develop rapidly and lead to death. [0003] In the "Guidelines for the Diagnosis and Treatment of Hand, Foot and Mouth Disease" issued by the National Health Commis...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P31/14A61P17/00A61P25/00A61K35/02A61K35/618A61K33/26
CPCA61K9/0014A61K9/0095A61K33/26A61K35/02A61K35/618A61K36/076A61K36/233A61K36/344A61K36/484A61K36/539A61K36/54A61K36/65A61K36/708A61K36/71A61K36/714A61K36/725A61K36/8888A61K36/9068A61K2236/331A61P17/00A61P25/00A61P31/14A61K2300/00
Inventor 王新锋邓安远涂华新李萌余玛俐樊伊娜彭虎
Owner JIUJIANG UNIVERSITY
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