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Needle puncture detection sheet

A technology for acupuncture and sheet use, which is applied to the field of cover materials for acupuncture detection, and can solve problems such as difficulty in determination, wrong use method, and foreign matter mixing.

Active Publication Date: 2020-04-21
KYODO INSATU KK KYODO PRINTING CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, there may be cases where a needle, typically an injection needle, is used improperly to pass the release material and pierce the rubber stopper without peeling off the release material due to a wrong use method or to intentionally mix foreign substances into the drug.
In such a case, it is not originally assumed that the needle is inserted through the release material, so it is difficult to determine whether the needle has penetrated the release material.

Method used

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  • Needle puncture detection sheet
  • Needle puncture detection sheet
  • Needle puncture detection sheet

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0222] (Manufacturing of sheets for acupuncture testing)

[0223] Pellets of high-impact polystyrene (HIPS) (manufactured by Toyo Styrol Co., Ltd., trade name "Toyostyrol HI H700 natural color") were hot-pressed to produce a film with a thickness of 100 μm, which was used as a whitening resin layer.

[0224] Adhere an easy open film (manufactured by Mitsui Chemicals Tohcello. Inc., trade name "CMPS013C#30") as a sealant layer to the whitened resin layer with an adhesive to create a structure with a whitened resin layer / sealant layer Acupuncture test sheet (release material).

[0225] (Evaluation of the visibility of needle puncture holes)

[0226] For the obtained sheet for acupuncture detection, an injection needle (manufactured by Terumo Corporation, trade name "NN-2138R", gauge length 21G (0.80 mm), needle length 1+1 / 2 inch (38 mm) was inserted from the surface of the whitened resin layer side. ), knife type R·B), and form a needle-punched hole with a diameter of 0.80 mm ...

Embodiment 2 and 3、 and comparative example 1

[0237] As the whitening resin layer, or instead of the whitening resin layer, a film with a thickness of 100 μm obtained by hot pressing the pellets of the resins shown in Table 1 was used, and a whitening resin layer was produced in the same manner as in Example 1. The needle-puncture detection sheet constituted by layer / sealant layer or resin layer / sealant layer was evaluated for the visibility and heat resistance of the needle-puncture hole. The results are shown in Table 1.

Embodiment 4

[0241] (Manufacturing of sheets for acupuncture testing)

[0242] Pellets of high-impact polystyrene (HIPS) (manufactured by Toyo Styrol Co., Ltd., trade name "Toyostyrol HI H700 natural color") were hot-pressed to produce a film with a thickness of 100 μm, which was used as a whitening resin layer. Cream-colored LDPE (manufactured by Tokyo Ink Co., Ltd., trade name "PEX 3110 CREAM", L value 76, thickness 100 μm) as a colored resin layer was adhered to the whitened resin layer using an adhesive. Next, an easy openfilm (manufactured by Mitsui Chemicals Tohcello.Inc., trade name "CMPS013C#30") as a sealant layer was adhered to the surface of the cream-colored LDPE film side with an adhesive to produce a whitening resin layer. A needle-puncture detection sheet having a composition of / colored resin layer / sealant layer.

[0243] (evaluate)

[0244] Using the obtained sheet for needle-puncture detection, evaluations of needle-puncture hole visibility and heat resistance were carr...

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Abstract

This needle puncture detection sheet 100 has a whitening resin layer 10 that, when punctured by an R.B type injection needle having a diameter of 0.80 mm to form a puncture hole 50, whitens and formsa whitened region 60 having a width of at least 0.2 mm around the puncture hole 40.

Description

technical field [0001] The present invention relates to a sheet for acupuncture detection, particularly a cover material for acupuncture detection. Background technique [0002] Liquid medicines such as infusions and injections are sometimes stored in containers with lids, for example, with rubber stoppers fitted into the openings. For example, a peeling material may be attached to the rubber stopper of the cap for the purpose of preventing contamination of the rubber stopper during storage, displaying it as an unused product, and the like. The medicine in such a container is used after the peeling material on the rubber stopper is peeled off and the injection needle is inserted into the rubber stopper. [0003] However, there may be cases where a needle, typically an injection needle, is passed through the release material and punctures the rubber stopper improperly without peeling off the release material due to a wrong use method or intentional mixing of foreign matter i...

Claims

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Application Information

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IPC IPC(8): A61J1/05B32B27/18B65D51/00B65D53/04
CPCB32B27/18B65D51/00B65D53/04A61J1/1406A61J1/18A61J1/05B32B27/32B32B2270/00
Inventor 山崎海里大泽梓萩尾由美子
Owner KYODO INSATU KK KYODO PRINTING CO LTD