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A non-irritating composition with whitening and moisturizing functions and its preparation method

A technology of moisturizing function and composition, applied in the field of non-irritating composition and preparation thereof, can solve problems such as unreported, and achieve the effects of reducing irritation, improving moisturizing performance, and improving whitening activity

Active Publication Date: 2021-04-06
美健极生物工程技术(广州)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In this field, Gynostemma pentaphyllum extract is applied to the preparation of anti-photoaging cosmetics (CN103191172A), and is used as a soothing active ingredient (CN105963188A), but as a whitening and moisturizing application, there is no report so far

Method used

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  • A non-irritating composition with whitening and moisturizing functions and its preparation method
  • A non-irritating composition with whitening and moisturizing functions and its preparation method
  • A non-irritating composition with whitening and moisturizing functions and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1, the preparation of Brassica chinensis ethanol extract

[0029] Take the root of Baizicai as raw material, wash it, crush it into a powder with a particle size of 40 mesh, add 80% ethanol solution of 8 times the total amount of the powder, heat and reflux for extraction twice, each time for 1.5h, and the extraction temperature is 70°C , Filtrate, combine the filtrates, remove ethanol under reduced pressure, and concentrate.

[0030] According to the above method, 75% and 65% ethanol solutions are used for extraction to obtain 75% ethanol extract and 65% ethanol extract respectively.

Embodiment 2

[0031] Embodiment two, the preparation of water extract of Chinese cabbage

[0032] Take the root of Baizicai as raw material, wash it, crush it into a powder with a particle size of 40 mesh, add 8 times the total amount of the coarse powder, and extract it twice with hot water at a temperature of 80°C, 6 hours each time, filter, combine the filtrate, and concentrate , that is.

Embodiment 3

[0033] Example 3. Comparison of Whitening Activity and Stimulus of Alcoholic Extract and Water Extract of Brassica chinensis

[0034] 3.1 Comparison of whitening activity

[0035] Each group of samples was diluted with disodium hydrogen phosphate-citric acid buffer solution (pH6.8, 0.05mol / L) to obtain multi-level concentration samples, and samples of each concentration were taken in glass test tubes, and tyrosinase solution was added respectively; at 30°C After reacting in a water bath for 10 minutes, add levodopa solution to each group of glass test tubes in turn, then react in a water bath at 30°C for 10 minutes, and measure the OD value at 475 nm. The experimental system is shown in Table 1.

[0036]

[0037] In the formula: T is the absorbance value of the sample tube, that is, the absorbance value of the solution after the sample reacts with tyrosinase; T 0 is the background absorbance value of the sample; C is the average value of the three times of the absorbance v...

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Abstract

The invention relates to a non-irritating composition with whitening and moisturizing functions and a preparation method thereof. The composition contains the active substance of Chinese cabbage and gypenoside as effective components. The present invention adopts the fermenting of the ethanol extract of Chinese cabbage to obtain the active substance with high inhibitory effect on tyrosinase by fermenting the ethanol extract of Chinese cabbage, and at the same time solves the problem of skin irritation caused by the ethanol extract of Chinese cabbage, which can be used as a whitening Active ingredients are used in the preparation of cosmetics. In addition, the present invention discovers the possibility of synergy between gypenoside and the above-mentioned active substances. When the two act in combination, not only the whitening activity of the composition is improved, but also the irritation of the composition is further reduced, which can be applied to Prepare non-irritating whitening products.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a non-irritating composition with whitening and moisturizing functions and a preparation method thereof. Background technique [0002] Gynura divaricata DC (Gynura divaricata DC) is a plant of the genus Sanqi in the family Compositae, also known as Panax notoginseng, Jiangtangcao, etc. It is widely used to treat hyperlipidemia and diabetes. For example, see Chinese invention patent applications CN102631391A, CN104644734A and CN110279873A. [0003] The most widely used is the aerial part of Chinese cabbage at present, and the extract of the aerial part of Chinese cabbage contains many components. Sterols, nucleosides, phenolic acids and esters, etc. Some scholars have analyzed the volatile oil content of different medicinal parts of Baizicai, and identified a variety of chemical components. Among them, the volatile oils of roots, stems and leaves contain the highest content of...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K8/63A61Q19/02A61Q19/00
CPCA61K8/63A61K2800/592A61K2800/782A61K2800/85A61Q19/00A61Q19/02A61K8/9789
Inventor 陈广文
Owner 美健极生物工程技术(广州)有限公司
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