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Plant essential oil hyaluronic acid stock solution bacteriostatic gel and preparation method and application thereof

The technology of plant essential oil and sodium hyaluronate is applied to the field of antibacterial gel of plant essential oil hyaluronic acid stock solution and preparation thereof, and achieves the effects of refreshing, smooth and moisturizing skin, reducing sticky feeling, and enhancing the antioxidant capacity of cells

Inactive Publication Date: 2020-07-17
青岛智博生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there is no product that adds plant essential oils to hyaluronic acid stock solution in the form of microemulsion to obtain antibacterial gel

Method used

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  • Plant essential oil hyaluronic acid stock solution bacteriostatic gel and preparation method and application thereof
  • Plant essential oil hyaluronic acid stock solution bacteriostatic gel and preparation method and application thereof
  • Plant essential oil hyaluronic acid stock solution bacteriostatic gel and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] A plant essential oil hyaluronic acid stock solution bacteriostatic gel, the essential oil hyaluronic acid stock solution bacteriostatic gel comprises the following raw material components in weight percentage: 0.05-0.80% macromolecular sodium hyaluronate (molecular weight 1.2 million daals Dalton or more), 0.03-0.60% small molecule sodium hyaluronate (molecular weight 1000–10000 Dalton), 0.3-3% plant essential oil, 0.5-10% surfactant, 0.03-10% gel matrix, 0.3-3.0 %No added preservative system, the used no added preservative system is prepared from 1,2-hexanediol, p-hydroxyacetophenone, and purified water, and the plant essential oils are clove oil, cinnamon essential oil, thyme essential oil, tea tree essential oil, lavender Any one or several of essential oils, the gel base is one of carbomer, hypromellose, hydroxyethyl cellulose, sodium alginate, xanthan gum or two or more of them in any proportion , The amount of the gel matrix determines whether the product is a ge...

Embodiment 2、 Embodiment 3

[0046] The difference from Example 1 is that the content of the components in the formula table is different, and the specific content is described in the following table.

[0047] Formula table of each material for 1kg product Unit: g

[0048]

[0049]

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Abstract

The invention discloses a plant essential oil hyaluronic acid stock solution bacteriostatic gel. The bacteriostatic gel is prepared from the following raw material components in percentage by weight:0.05 to 0.80 percent of macromolecular sodium hyaluronate, 0.03 to 0.60 percent of small molecular sodium hyaluronate, 0.3 to 3 percent of plant essential oil, 0.5 to 10 percent of a surfactant, 0.03to 10 percent of gel matrix, 0.3 to 3.0 percent of a non-additive preservative system and purified water. The plant essential oil hyaluronic acid stock solution bacteriostatic gel has bacteriostatic effect on staphylococcus aureus and escherichia coli, is suitable for skin bacteriostasis and daily nursing, and has the effects of moistening and moisturizing. The plant essential oil hyaluronic acidstock solution bacteriostatic gel product disclosed by the invention has the advantages of sparkling and pure and beautiful appearance and excellent stability, is fresh, smooth and moistening in skinfeeling as a water-based gel, can reduce the sticky and greasy feeling of simply using the essential oil, and makes of the plant essential oil fragrance lasting. The sodium hyaluronate and the essential oil can be compounded to nourish the skin, inhibit bacteria, kill bacteria, diminish inflammation, and relieve dryness of the skin.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to a plant essential oil hyaluronic acid stock solution antibacterial gel and a preparation method and application thereof. Background technique [0002] Natural plant essential oils have low solubility in aqueous systems, are unstable, volatile, and are easily oxidized and decomposed after being heated. However, the skin feels sticky and irritating after direct use. In order to be applied in cosmetic product formulations, it is necessary to add The solubility and stability of essential oils in the water phase, so the preparation of essential oils into emulsions is a common process, but emulsions are a thermodynamically unstable system. The microemulsion can not only disperse the plant essential oil stably and evenly in the aqueous medium, but also increase the amount of essential oil dissolved in the water phase, and is a thermodynamically stable system. [0003] Sod...

Claims

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Application Information

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IPC IPC(8): A61K8/92A61K8/73A61K8/04A61K8/06A61Q17/00A61Q19/00A61Q19/08A61Q17/04A61L26/00
CPCA61K8/922A61K8/735A61K8/042A61K8/068A61K8/062A61Q17/005A61Q19/00A61Q19/08A61Q17/04A61P17/02A61L26/0066A61L26/0061A61L26/008A61L26/0057A61L26/0023A61L2300/30A61L2300/232A61L2300/412
Inventor 俞超田德娟王玲
Owner 青岛智博生物科技有限公司
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