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Enema liquid for treating sow constipation and preparation method thereof

A sow constipation and enema technology, which is applied to medical preparations with non-active ingredients, medical preparations containing active ingredients, and pharmaceutical formulas, etc., can solve the problem of uneven distribution of active ingredients, different effects of soapy water, and soapy water Instability and other problems, to achieve the effect of strong operability of the preparation process, exact therapeutic effect, and promotion of intestinal fluid exudation

Pending Publication Date: 2020-08-07
李会芳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, when soapy water is used clinically, firstly, it needs to be used in a large amount. Usually, 2000-3000ml needs to be poured at a time to be effective, which is more stressful to sows.
The second is that the clinical effect of soapy water varies. Some pigs can expel constipation quickly after enema, but a large part of them need to wait for more than 4 hours, and some pigs even need repeated treatment several times to see the effect.
The third is that soapy water is unstable, and floating flocculent substances are prone to appear after dissolving in water, and the active ingredients are unevenly distributed, thus offsetting part of the efficacy

Method used

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  • Enema liquid for treating sow constipation and preparation method thereof
  • Enema liquid for treating sow constipation and preparation method thereof
  • Enema liquid for treating sow constipation and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1-11

[0023] In order to make the description concise, the weight composition of the enema solution for treating constipation in sows described in Examples 1-11 is given in the form of a table below, as shown in Table 1 for details.

[0024] The weight composition of every 100g of the present invention in the embodiment 1-11 of table 1

[0025]

[0026] The preparation method of the enema liquid that is used for the treatment of sow constipation described in embodiment 1-11, comprises the following steps:

[0027] (a) Mix liquid paraffin and 1,2-propanediol, stir evenly, then add Span-65 and Tween-81 respectively, stir again, and obtain system 1;

[0028] (b) Mix medical stone powder, magnesium sulfate, benzalkonium bromide and sodium carboxymethylcellulose evenly, pass through an 80-mesh sieve after crushing, add to system 1, and stir again to obtain system 2;

[0029] (c) Preheat system 2 to 40°C to 50°C and keep it at a constant temperature. Gradually add the remaining amount...

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Abstract

The invention discloses an enema liquid for treating sow constipation and a preparation method thereof. Every 100g of the enema liquid comprises the following components by weight: 0.1-5.0g of medicalstone powder, 2.0-6.0g of Span-65, 1.0-10.0g of Tween-81, 0.01-0.2g of benzalkonium bromide, 1.0-5.0g of liquid paraffin, 1.0-10.0g of 1, 2-propylene glycol, 1.0-8.0g of magnesium sulfate, 0.5-5.0g of sodium carboxymethyl cellulose and the balance deionized water. The enema liquid disclosed by the invention has a remarkable treatment effect on constipation of sows, is safe in clinical use and exact in effect, can quickly help to eliminate constipation after rectal drenching, and is thorough in treatment and not easy to relapse in the later period. The invention further discloses a preparationmethod, the process operability is high, raw materials and auxiliary materials are easy to purchase, production conversion is facilitated, and the market prospect is good.

Description

technical field [0001] The invention belongs to the technical field of veterinary medicines, and in particular relates to an enema solution for treating constipation in sows and a preparation method thereof. Background technique [0002] Constipation in sows is a common medical disease in the production process of sows. It is mainly caused by the secret knot, drying, and accumulation of intestinal contents, which will stagnate in the colon and rectum, resulting in feces being blocked and unable to descend. There are many factors that cause this disease, such as the growing uterus of sows in the late pregnancy, oppressing the colon and rectum, causing rectal paralysis and causing constipation; sows who lack exercise for a long time have weakened intestinal peristalsis, which can also cause this disease; insufficient drinking water Sometimes the feces tend to dry out and stay in the rectum, causing constipation; long-term abuse of antibiotics leads to intestinal microecologica...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61K47/38A61K47/26A61K47/06A61K47/02A61K33/00A61K31/14A61P1/10
CPCA61K9/08A61K9/0031A61K47/38A61K47/26A61K47/06A61K47/02A61K33/00A61K31/14A61P1/10A61K2300/00
Inventor 马超锋赵协李乐王成龙郭良李乾符旺李会芳
Owner 李会芳
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