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A Rapid Quantification of T1ρ Based on Magnetic Resonance Fingerprinting

A magnetic resonance and fingerprint technology, applied in diagnostic recording/measurement, medical science, diagnosis, etc., can solve the problems of long T1ρ imaging time and so on

Active Publication Date: 2021-08-20
FUDAN UNIV
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Problems solved by technology

[0008] The purpose of the present invention is to solve the problem of long T1ρ imaging time and provide a method for fast quantitative T1ρ based on magnetic resonance fingerprint imaging

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  • A Rapid Quantification of T1ρ Based on Magnetic Resonance Fingerprinting
  • A Rapid Quantification of T1ρ Based on Magnetic Resonance Fingerprinting
  • A Rapid Quantification of T1ρ Based on Magnetic Resonance Fingerprinting

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Embodiment Construction

[0029] The specific embodiment of the present invention will be described with reference to the present invention to the examples.

[0030] Sequence Design: The sequence implementation of the present invention is implemented on the Brooke 11.7T magnetic resonance system, and the software version is Paravision 6.01, and the receiving coil is a 4-channel transceiver cylindrical coil. The sequence is excited to use different TSL, FA, TR and TE, where TSL ranges from 0ms to 50ms, FA from 5 degrees to 80 degrees, TE from 11 ms to 21 ms, TR varies from Perlin noise mode, ranging from 25 ms to 200 ms.

[0031] Conventional fingerprint imaging methods typically set to 1000 times, and the relatively accurate value can be obtained, and the present invention also uses a number of excitation of 1000 times to scan seven water molds.

[0032] The seven water molds were measured using a traditional T1ρ imaging sequence based on RARE-collected T1ρ imaging sequences, and the sequence was fitted wi...

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Abstract

The invention belongs to the technical field of magnetic resonance imaging, in particular to a method for rapidly quantifying T1ρ based on magnetic resonance fingerprint imaging. The method of the present invention includes adding a spin-lock preparation pulse before the traditional MRF sequence, and through reasonable modeling, the T1ρ evolution of the signal is fused with the T1, T2 evolution of the signal, so that the signal collected at each time point includes T1, T2 and Components of T1ρ. Design the sequence parameters TSL, FA, TR, and TE with pseudo-random changes, and establish a dictionary of different relaxation time value combinations through the evolution of the magnetization vector in the Bloch equation, and match the actually collected image sequence with the dictionary to quantify T1ρ, T1 and T2 values. Compared with the traditional exponential fitting method, the method for quantifying T1ρ of the present invention can greatly shorten the scanning time, and is expected to have greater application value in T1ρ imaging.

Description

Technical field [0001] The present invention belongs to the field of magnetic resonance imaging, and in particular, the method of rapid quantification T1ρ based on magnetic resonance fingerprint imaging. Background technique [0002] Magnetic Resonance Imaging, MRI is a non-invasive, high spatial resolution, high-tissue contrast, oriental imaging technology. Magnetic resonance imaging has a rich organizational contrast, which is a clinically important diagnostic tool, is widely used in clinical diagnosis, neuroscience and mental illness. [0003] Magnetic Resonance Fingerprinting, MRF was initially proposed by MA, etc. (MA D, Gulani V, Seiberlich N, et al. Magnetic Resonance Fingerprinting.Nature. 2013; 495 (7440): 187-192), MRF adopts pseudo The sequence parameters of random change are data acquisition, and the Dictionary is established by the Bloch equation simulation signal. The dictionary contains a large number of different parameters (such as T1, T2) combination, which will...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/055
CPCA61B5/055A61B5/72
Inventor 王前锋王鹤戴飞
Owner FUDAN UNIV
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