The invention relates to a composite layered anti-interference controller, in particular to a design of the composite layered anti-interference controller in a type of multisource jamming control system. The anti-interference controller is designed aiming at the multisource jamming control system containing external model description disturbance, random disturbance and energy-bounded disturbance. Firstly, a reduced-order disturbance observer is structured to estimate and counteract the external model description disturbance of the multisource jamming control system; secondly, the controller having H infinity and guaranteed cost performance index is structured, wherein, the H infinity performance index can be used for inhibiting the energy-bounded disturbance in the system, and the guaranteed cost performance index can be used for inhibiting the random disturbance in the system as well as optimizing the upper bound of variance; the composite layered anti-interference controller can be formed by the reduced-order disturbance observer and the feedback controller with a state of robust H infinity and guaranteed cost; finally, based on convex optimization algorithm, gain array of the composite layered anti-interference controller can be solved. The invention has the advantages of strong anti-interference property, convenient design and the like, and can be applied to a navigation and control system of aerospaceplane, etc.