The invention discloses a long bone resetting robot in series-parallel connection, which comprises a serial connection part and a parallel connection part, wherein the serial connection part comprises a near-end fixing mechanism and a far-end fixing mechanism which are connected or disconnected through a positioning rod; each of the near-end fixing mechanism and the far-end fixing mechanism comprises a fixing plate, a locking bolt, a connecting rod, a connecting rod mounting base, a bracket rod and a latch clamping mechanism; the latch clamping mechanism comprises a connecting bolt and a latch; the parallel connection part comprises a far-end platform panel, a far-end platform connecting plate, a far-end platform pressing plate, a near-end platform panel, a near-end platform connecting plate, a near-end platform pressing plate and a stretching rod mechanism; and the stretching rod mechanism comprises a connecting hinge, a sleeve and a connecting rod. The long bone resetting robot in series-parallel connection is mainly used for realizing a function of assisting the resetting of long bone fracture by the robot under a closed condition. The long bone resetting robot in series-parallel connection has the characteristics of flexible mechanism, large work space, convenience in operation, and the like, and has an excellent application prospect.