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The present invention relates to compounds of the formula

and pharmaceutically acceptable salts, solvates or tautomers thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds, and the uses of such compounds, in particular for the treatment of pain.

The present invention relates generally to telecommunications, and more specifically, to an improved operating system and apparatus for telecommunications networks. Currently, the majority of telecommunication services are provided over the Public Switched Telephone Network and Internet. Existing telephony systems suffer from a number of problems including system complexity, limited access and implementation of services on fixed hardware, which results in long time to bring new products to market. Internet applications cannot guarantee quality of service in the transmission. These systems are therefore inflexible and inefficient which limits their ability to carry new services. The invention provides a distributed and real-time operating system for use over varied telecommunications networks. As well, methods of implementing synchronized execution, fault tolerance and loading management over this network, are also described. The application of this operating system to existing networks allows new services to be provided.

The invention discloses an extracting method of nickel, which comprises the following steps: breaking nickel oxide into small blocks; pouring ore pulp with density at 20-60% into autoclave; adding sulfuric acid and reducer; heating; pressurizing; heating; reinforcing the leach; controlling the temperature between 100 and 200 deg. c; controlling the pressure below 1. 6Mpa; sedimenting leached liquid to obtain nickel through solid sediment agent; or extracting leached liquid; separating nickel out of liquid; condensing; purifying; obtaining the electrodeposited nickel or nickel sulfate.

The present invention relates to a brake holder of a floating-caliper disc brake for motor vehicles at which brake pads arranged on either side of an associated brake disc are displaceably mounted. To ensure ease of displaceability a brake pad guide spring is provided that extends between the brake holder and the brake pads. For ease of mountability of both the brake pads and the brake pad guide spring, it is arranged for that the brake pad guide spring is mountable on the brake holder in a generally radial direction and is locked at the brake holder in both radial and axial directions by means of at least one fixing clamp, and at least one spring arm is designed at the brake pad guide spring and fixes at least one brake pad under spring bias in position on the brake holder in a clearance-free manner. These provisions not only improve the mountability of a brake of this type but also the rattle-free resilient arrangement of the brake pads.

The invention relates to an twice-separation dust cup of dust collector, which comprises a casing, an air outlet arranged on the casing, an air intake port in tangency with the casing circumferential wall and a segregator arranged in the casing, the segregator is provided with an air intake port with a shielding hood arranged below, the segregator is also provided with two inside and outside pipes arranged coaxially, the air intake port of the segregator is in communication with the air outlet port of the dust cup through the inner tube, the air intake port of the separator is formed by blades by ring form array, the horizontal position of the segregator's air intake port is lower than the dust cup air intake port. The outer volume of the product is substantially reduced.

Provided are a nanoporous tungsten carbide catalyst that can be used as an electrode of a fuel cell and a preparation method thereof. The nanoporous tungsten carbide catalyst includes tungsten carbide crystalline particles and has nanopores of a mean pore diameter ranging from 2 nm to 5 nm and a nanopore volume of 0.08 to 0.25 cm³ per gram of the catalyst. The nanoporous tungsten carbide catalyst or the nanoporous tungsten carbide catalyst supported with a metallic active component has high electrochemical activity and enhanced resistance to poisoning by carbon monoxide (CO). Therefore, even after use for an extended period of time, the nanoporous tungsten carbide catalyst of the present invention can maintain a long-term high catalytic activity. In addition, since the nanoporous tungsten carbide catalyst of the present invention has small pore sizes and a large pore volume, which are advantageous for dispersing metallic active components, much higher catalytic activity can be demonstrated only with a small amount of the metallic active component. Accordingly, an electrode for use in a fuel cell and a fuel cell employing the electrode can be fabricated in a cost-effective manner, compared to the prior art in which a considerable amount of expensive, precious metal catalysts are used.

A write-once high density optical information recording medium, with the recording medium made of a material having a formula of A_xB_yC_z, is formed by a special thin film coating process. There is a good contrast for optical reflectivity between the recorded marks and the non-recording areas, and the recorded marks can not be removed to be rewritten. The write-once high density optical information recording medium is easier to manufacture and is suitable for mass-production. And, the write-once high density optical information recording medium has good recording characteristics under blue laser wavelength, so that the data quality is improved remarkably and the data jitter is reduced. The multiple-layer film structure of the storage medium on the substrate of the optical disc includes a first protective layer, a recording layer, a second protective layer, and a reflective layer covering the second protective layer.

The invention discloses an anode support tube type solid oxide fuel cell and an assembling method thereof, which relates to the cell application field. A metal connecting body shell cover of the cell is arranged on the top end of an anode support electrolyte tube, seals the gas of the end, and simultaneously exports the electric current of the anode. The electric current inside the anode is collected by porous Ni felt and guided to the closed end. At the other end of a cell tube, a heat-resisting ceramic tube or a heat-resisting alloy tube is used as a gas-guide tube, and the gas-guide tube preheats or reforms normal temperature fuel gas simultaneously when guiding the normal temperature fuel gas. When the gas is imported to the closed end, temperature and composition of the gas meet the requirement of power generation, so that power generation can be carried out during inverse flow of the gas. Remaining fuel tail gas after power generation combusts instantly when getting in touch with the air at the mouth of the tube, and the heat energy is recovered. Anode support tube type solid oxide fuel cell and assembling method thereof have the advantages that: the electric current collecting position is moved to the closed end from the inner side of the cell, and the structure of an assembled electric pile is simple and compact, and the value of the power can be adjusted.

The invention discloses a lithium-rich manganese-based cathode material and a preparation method thereof, a positive electrode piece and a lithium ion secondary battery. A sodium-containing layered composite metal oxide NaaLixNiyMnzM1-x-y-zO2 is taken as a precursor, the sodium-containing layered composite metal oxide NaaLixNiyMnzM1-x-y-zO2 is subjected to ion exchange in a fuse salt to prepare alithium-rich manganese-based cathode material having the chemical constitution of Lix+a+bNiyMnzM1-x-y-zO2, wherein 0.62<=a<=1, 0<=x<=0.4, 0<=y<=0.5, 0.5<=z<=1, and 1<=x+a+b<=1.5, M is at least one element in the group of Mg, Al, Ti, V, Fe, Co, Cu, Zn and Zr, and 0.7<=x+y+z<=1. The lithium-rich manganese-based cathode material is prepared through ion exchange in the novel fuse salt, has high energydensity, is more suitable for development of the high energy density cathode material, has very high first-time charge-discharge efficiency and good cycle features, and can effectively overcome the problems in the prior art.

The invention relates to an attitude determination system and method of a small unmanned aerial vehicle, which have the advantages of low cost, low consumption, simple algorithm and small calculated amount. The system comprises an angular rate gyro chip, a triaxial electronic compass chip, a triaxial accelerometer chip and a microcontroller chip, wherein the angular rate gyro chip is used for measuring rolling, pitching and yawing angular rates of the unmanned aerial vehicle; the triaxial electronic compass chip is used for measuring a flight path azimuth angle, namely a yawing angle, of the unmanned aerial vehicle in a flight process; the triaxial accelerometer chip is used for measuring a component of the gravity in a body coordinate axis of the unmanned aerial vehicle; the microcontroller chip is connected with the angular rate gyro chip, the triaxial electronic compass chip and the triaxial accelerometer chip through I<2>C buses and is used for acquiring measuring data of sensors and determining the real-time attitude of the unmanned aerial vehicle according to the acquired data and the attitude determination method. The method comprises the steps of establishing an initial direction cosine matrix between a body coordinate system and an inertial coordinate system of the unmanned aerial vehicle, updating an attitude direction cosine matrix, standardizing the direction cosine matrixes and counting a corrected triaxial angular speed and triaxial attitude angles of the unmanned aerial vehicle.

The invention provides an antistatic waterproof functional woven fabric and a method for preparing the same. The method includes weaving, type approval, finishing and shaping. Fiber materials for the antistatic waterproof functional woven fabric include, by weight, 20-100% of antistatic polyester fibers or polyamide fibers. Type approval includes waterproof treatment at the temperatures of 120-230 DEG C; antistatic functional powder with the size of 30-150 nm is used when the fiber materials are prepared. The antistatic waterproof functional woven fabric and the method have the advantages that antistatic fibers are creatively added into the antistatic waterproof functional woven fabric for current waterproof fabric treatment modes, accordingly, accumulation of electrostatic charge can be effectively reduced, attenuation half lives of frictional electrostatic voltages and the electrostatic charge can be shortened, and the garment fabric has appropriate, attractive, healthcare and safe performance.

The invention relates to a processing device of polyester and viscose blended yarn in binary structure and a method thereof. A three-port collector (5) is fixed at the front part of a rear roller (11), a V-shaped opening collector (10) is fixed in a position close to the rear roller (11) between the rear roller (11) and a middle roller (12), openings in the same structure are respectively arranged at the front part, the middle part and the rear part of the three-port collector (5), a middle inlet (8) is arranged in the middle, inlets (6 and 7) at both sides are arranged on the periphery, openings are respectively arranged above the three inlets (6, 7 and 8), the rear opening is in a V-shaped structure, a round hole outlet (9) is arranged below, and the V-shaped opening collector (10) is rectangular and provided with a V-shaped groove in the middle. The invention can solve the problem of uncontrollable fiber mixing in the prior art.

The invention discloses a preparation method of a microcarrier used for cell three dimensional multiplication culture, and belongs to the field of tissue engineering material. According to the preparation method, Poly-L-lactic acid (PLLA) is taken as a matrix, gelatin is taken as a dispersant, and composite microspheres are prepared; the particle size of the composite microspheres is adjusted viacontrolling the concentration of a PLLA dichloromethane solution, the mass ratio of nano-hydroxyapatite (nHAp) to PLLA, and the using amount of gelatin; the PLLA is taken as the matrix to ensure the mechanical strength and biological degradability of a support; composite nHAp is capable of improving the osteo inductivity and the conductivity of the support, and at the same time, assisting PLLA toimprove cell osteogenic capability, and avoiding damage of cells under an overly acidic environment; the existing of nHAp is capable of forming a large amount of small pores on the surfaces of the PLLA microspheres, the existing of the small pores is capable of improving the mass transfer capability of the support, and providing cells with more abundant attachment sites. The microcarrier possessesexcellent biological performance on osteoblasts, and is suitable to be used in the field of bone tissue engineering.

The present invention provides a resist development processor consisting of a development processing chamber for storing a resist substrate having an exposed resist on the substrate and for developing the exposed resist by means of a development solvent consisting of a supercritical fluid; and a supercritical fluid container for storing a supercritical fluid, where the supercritical fluid container is connected to the development processing chamber through a valve.

The present invention relates to a self-propelled working machine, especially in the form of a surface milling machine, such as asphalt-milling machine or snow-milling machine comprising a main operating unit and/or a drive unit, which is operable in a steady-state or near steady-state operating status and is drivable by a drive device comprising at least an electrical motor, the electrical motor being associated with a start-up including a frequency converter for the limitation of starting current. The invention also relates to a process for operating such a self-propelled working machine. According to the invention an operating circuit for steady-state operation is provided, comprising a jumper for bridging the frequency converter following starting or reaching steady-state operational status. Optionally, the jumper is switchable to activate or inactivate the frequency converter of the start-up circuit, respectively.

The invention provides a novel Xtandi crystal form shown in a chemical formula (I) and a preparation method thereof, and particularly discloses a B1 crystal form Xtandi and a preparation method thereof. The Xtandi disclosed by the invention has the advantages of steady crystal form and good solubility, and the Xtandi is suitable for medicine development. The preparation method is safe and simple, and is strong in maneuverability.

The invention discloses a pressurized acid-leaching potassium extracting technology for potassium feldspar. Products such as potassium sulphate, aluminum hydroxide, quartz and gypsum are obtained from the raw materials such as potassium feldspar powder, fluorosilicic acid, sulfuric acid and cyclic dilute sulphuric acid. The pressurized acid-leaching potassium extracting technology disclosed by the invention is low in sulfuric acid consumption, high in percent conversion, low in reaction temperature, small in energy consumption in production, and low in potassium extraction cost; and various ingredients in potassium feldspar ore are comprehensively utilized.

The invention relates to a medium and trace element nutritional synergist with abundant sulfur and zinc and application of the medium and trace element nutritional synergist. The medium and trace element nutritional synergist comprises 38%-75% of medium and trace element components, 0.5%-4% of dispersing agents, 0.5%-6% of wetting agents, 0.5%-5% of film-forming agents, 0.5%-5% of coalescing agent, 0.5%-5% of fillers, 19.5%-40% of water and 0.5%-2% of pigments. Various components are uniformly mixed with one another to obtain a product which is flow emulsion, and the coalescing agent is ethylalcohol or texanol ester alcohol. The application includes enveloping granular macro-element fertilizers and powdery fertilizers with the medium and trace element nutritional synergist for providing medium and trace element nutrition such as the sulfur and the zinc for the fertilizers; coating seeds with the medium and trace element nutritional synergist for improving the vitality of the seeds, increasing the germination rate of the seeds and improving the activity of seedlings; spraying the medium and trace element nutritional synergist on leaf surfaces for quickly providing the medium and trace element nutrition such as the sulfur and the zinc for crops; applying the medium and trace element nutritional synergist to drip irrigation and fertilization, allowing the medium and trace elementnutritional synergist and other macro-element fertilizers to be fed to positions near the root systems of the crops and further allowing the medium and trace element nutritional synergist to be absorbed by the root systems of the crops. The medium and trace element nutritional synergist and the application have the advantages that a medium and trace element nutritional layer can be quickly and efficiently formed on the surface of each fertilizer or the surface of each seed without drying, and the medium and trace element nutritional synergist is excellent in leaf surface spraying performanceand suspension fertilizer performance.

The invention relates to a lost foam digital processing method and equipment thereof. The method steps of the invention include: dissecting the CAD model of the lost foam, converting the CAD model into numerical control codes, cutting and processing the blank of the lost foam, removing waste, and post-processing the appearance of the lost foam. The equipment of the present invention includes a base (50), a bed (70), a multi-axis motion system (80), a drive system (90), a cutting system (60), a waste adsorption collection system (40) and a special control system (10 ). The method and equipment of the present invention realize immediate negative pressure chip removal through the hollow-structured machining spindle (62) and cutting tool (61), and the waste chips will not stick to the cutting tool (61) and affect processing. The invention not only improves the precision and quality of products, saves raw materials, but also shortens the research and development cycle of new casting products, and is especially suitable for single-piece, small-batch large and medium-sized castings for lost foam casting.

The invention discloses an evening essence B-casein phosphopeptide-chitosan nano particle, a preparation method and applications thereof. The preparation method comprises the following steps: preparing a CPPs solution, a CS solution, and an OEB solution, adding three solutions in a certain sequence, evenly mixing, controlling the mass percentage of CPPs and OEB of the final solution and the total concentration of CPPs, CS, and OEB of the solution, adjusting the pH value of the system to obtain nano spheres; then adding genipin to fix the nano spheres to obtain nano suspension, and subjecting the nano suspension to centrifugation and drying to obtain the evening primrose essence B-casein phosphopeptide-chitosan nano particles. The nano particle has the advantages of adjustable particle size, high embedding rate, pH responding property, green, energy saving, safety, stomach acid resistance, and sustain-released function, and can be widely used in the fields such as pharmacy, food, healthcare product, and the like.

The invention relates to a crystal form of an acotiamide hydrochloride hydrate shown as a chemical formula (I) and a preparation method thereof. Specifically, the present invention discloses an acotiamide hydrochloride hydrate of crystal form A and a preparation method thereof, and the XRPD characteristic peak is shown as in a figure 1. The preparation method of the acotiamide hydrochloride hydrate of crystal form A provided by the invention is safe, simple and strongly operable, the prepared acotiamide hydrochloride hydrate of crystal form A has single crystal form, stable property and good repeatability, and suitable for drug development.

The invention relates to a natural vegetable fiber reinforced geopolymer composite material and a preparation method thereof, belonging to the field of ornamental molding and environmental-friendly materials. The composite ornamental molding material comprises the following materials according to weight percentage, 30 to 70 percent of low-temperature calcination kaolinite clay grain diameter of which is 200 meshes, 5 to 40 percent of waste flax ultrashort fiber, 0 to 30 percent of fly ash of power plants or 0 to 30 percent of carbide slag degree of fineness of which is 150 meshes, 5 to 10 percent of booster, 4 to 5 percent of accelerant, NaHO water solution, hardener concentration of which is 12 percent, and 0 to 1 percent of paint, wherein the accelerant is industrial sodium silicate; and modulus M equals to 3.3. The composite ornamental molding material can replace the traditional ornamental molding materials like plaster, cement and clay, is suitable for manufacturing such products as ashlar artwork, embossed wall bricks, sculptures, floor bricks, and the like for architectural ornaments, and has low cost and better performance than traditional materials.