57results about How to "Single crystal form" patented technology

The invention discloses a lithium-titanium oxide type lithium ion sieve absorbent and a method for preparing a precursor thereof, and relates to a method for preparing an inorganic absorbent for absorbing enriched lithium from salt lake brine, seawater and other liquid lithium resources. The method is characterized in that: titanium dioxide and lithium salt are taken as raw materials, ground by a ball grinder and dried so as to prepare a precursor Li2TiO3 of an ion sieve through a high-temperature solid-phase roasting method; and the lithium is eluted from the precursor Li2TiO3 by inorganic acid to prepare an ion sieve H2TiO3. The method has the advantage of simple technology, and the obtained ion sieve has the advantages of low solution loss and high adsorption capacity.

The invention relates to the pharmaceutical chemistry field, and discloses a quzhazhigan crystal and a preparation method and an application thereof. The quzhazhigan crystal of the invention has a single crystal form, high purity, good stability, high solubility and bioavailability. The preparation method of the quzhazhigan crystal of the invention has simple operation, easily available raw materials, low production cost, continuous operation, and is applicable to mass preparation of the quzhazhigan crystal.

The present invention relates to a method for preparing ferrous oxalate. Said method uses ferrous sulfate and oxalic acid as raw material, and includes the following steps: pretreatment of ferrous sulfate, said pretreatment includes: water-washing ferrous sulfate and inhibiting hydrolysis of its aqueous solution; mixing the pretreated ferrous sulfate with ammonium oxalate and oxalic acid according to the mole ratio of 3:7-8:2 to obtain their mixed solution; making said mixed solution produce reaction for 10-20 min at 65-95 deg.C, then standing still for 2-4 h, separating, washing and drying so as to obtain the invented product ferrous oxalate.

The invention provides a method for preparing a doped perovskite structural composite oxide, which comprises two steps, namely preparation and sintering of sol-gel. The preparation of the sol-gel comprises the following steps of selecting an element containing Sr or Zr as a group A element and selecting an element containing three elements selected from Ti, Fe, Cu, Pd and Mn as a group B element to prepare perovskite structural composite oxide gel of which the general formula is AB1-x-yB'xB''yO3-epsilon, wherein x and y are more than 0 and less than 0.5; and epsilon is more than -0.5 and less than 0.5 and is an oxygen lattice defect number. The obtained gel is sintered in a muffle furnace of which the temperature can be controlled by a program to obtain a perovskite oxide material which has a high crystallization degree, a single crystal form and a compact surface. The perovskite oxide material can be applied to a piezoelectric material or an electronic apparatus and can also be made into a compact ion conducting oxygen-permeable membrane for oxygen separation.

The invention discloses a preparation method of electrolytic manganese dioxide for positive material-lithium manganate of a lithium battery. The method comprises the steps of (1) mixing manganese oxide ore powder with pyrite powder, and then adding the mixture and sulfuric acid into a leaching tank with continuous stirring according to a certain material ratio for reacting, thus obtaining a manganese sulfate solution, wherein the process reaction temperature is 85-90 DEG C and the reaction time is 3h-4h; (2) removing potassium; (3) purifying to remove impurities; (4) carrying out electrolysis; (5) dissolving; (6) carrying out high-temperature calcination to obtain the electrolytic manganese dioxide product. The electrolytic manganese dioxide prepared by the method is single in crystal form and has a pure beta type structure, so that lithium can be easily embedded in and removed out from the electrolytic manganese dioxide; the electrolytic manganese dioxide is very low in the content of impurities, so that the lithium manganate produced from the electrolytic manganese dioxide has excellent electrical property and safety performance.

The invention, belonging to the technical field of inorganic salt materials, provides a preparation method of barium carbonate powder. The method comprises the following steps: selecting proper barium salt, adding a fresh prepared morphology regulator (water-soluble cellulose derivative), regulating the pH value to a proper value, using high pressure/supercritical carbon dioxide as a carbonic acid source (with certain temperature and pressure), reacting for different time to obtain a white turbid liquid; and separating and drying the white turbid liquid to obtain a required product. According to the invention, the batch production of barium carbonate powder with different morphologies (rodlike-type, dendritic-type, dumbbell-type, ball-type, symmetric-type and the like) and dimensions (500 nm-30 mu m) can be realized, the obtained barium carbonate product has good dispersibility and has a purity of more than 99.8 %; in addition, the method has the advantages of wide source of raw materials, low price, easy operation, little pollution of the used solvents, and no toxic and harmful effect, satisfies the requirement of green chemistry, and has the potential of large scale production.

The invention relates to a preparation method of anhydrous and non-solvation A crystallization parecoxib sodium. The method comprises the following steps: 1,2-phenylacetophenone and pyrrolidine are condensed to generate 1-(1,2-diphenylvinyl)pyrrolidine, then acetylation is carried out, and 4,5-dihydro-5-methyl-3,4-dibenzyl-5-isoxzzole alcohol are subjected to cyclization under sodium acetate and hydroxylamine hydrochloride. The compound is directly reacted to chlorosulfonic acid, dehydration and chlorine sulfonation reaction are carried out, and then valdecoxib can be obtained through ammonification, valdecoxib is refined, then is subjected to acetylation to obtain parecoxib, and salt forming is performed to obtain the target compound parecoxib sodium.

The invention relates to a crystal form of an acotiamide hydrochloride hydrate shown as a chemical formula (I) and a preparation method thereof. Specifically, the present invention discloses an acotiamide hydrochloride hydrate of crystal form A and a preparation method thereof, and the XRPD characteristic peak is shown as in a figure 1. The preparation method of the acotiamide hydrochloride hydrate of crystal form A provided by the invention is safe, simple and strongly operable, the prepared acotiamide hydrochloride hydrate of crystal form A has single crystal form, stable property and good repeatability, and suitable for drug development.

The invention provides a clean production method of high-purity copper phthalocyanine. The method comprises following steps: (1), synthesis: alkylbenzene is added to a condensation tank, phthalic anhydride is continuously added after the temperature is increased, urea, cuprous chloride and ammonium molybdate are added after phthalic anhydride is dissolved, the components are subjected to a reaction, and a crude copper phthalocyanine product is prepared; (2), refining: copper phthalocyanine slurry is prepared from the crude copper phthalocyanine product and added to a mixed solution N preparedfrom dilute sulfuric acid and a cosolvent, heating and stirring are performed until the crude copper phthalocyanine product is completely dissolved, then water is dropwise added until copper phthalocyanine crystals are not separated out, filtering is performed, a filter cake is subjected to ethanol washing, water washing, filtering and vacuum drying, and the high-purity copper phthalocyanine product is obtained; (2), waste liquor recovery: a large amount of filter liquor produced in a reaction process is adsorbed by ion exchange resin, neutralized, concentrated, evaporated and centrifuged, andan ammonium sulfate product is prepared. Copper phthalocyanine prepared with the method is high in purity and has single crystal form, good coloring effect and excellent color stability, meanwhile, tail gas and wastewater in the production are effectively treated, and economic benefits of energy conservation and emission reduction are obtained.

The invention relates to an esomeprazole magnesium dihydrate preparation method. The method comprises the following steps: dissolving an esomeprazole magnesium trihydrate in a single or mixed solvent, adding an adverse solvent, stirring for precipitating a solid, separating the solid, washing the solid, and drying the solid to obtain an esomeprazole magnesium dehydrate having an A crystal form. The method has the advantages of economy, simple operation, single product crystal form, and high repeatability, and is suitable for the industrialized production.

The invention discloses a preparation method of an antimony (III) trioxide cubic crystal. The preparation method comprises the following steps: step one, dissolving antimony trichloride into glycol; step two, heating the solution to a temperature of 25-90 DEG C, and introducing ammonia gas into the solution until the pH value of the solution is greater than 8; step three, after the reaction, mixing the obtain solid-liquid mixture with distilled water, and stirring to carry out hydrolysis; step four, after the hydrolysis, carrying out centrifugal separation, washing the obtained substances until no chlorine ion exists on the substances, and drying so as to obtain the antimony (III) trioxide cubic crystals. The provided preparation method has the following advantages: (1) the raw materials are cheap, and the technology is simple; (2) the organic solvent can be recycle and reutilized, the recycling cost is low, and the production cost is reduced; (3) the crystal form of the obtained product is single, the crystallization is complete, and thus the crystals can be easily dispersed in plastic and paints and attached on fibers.

The present invention relates to betrixaban salts as shown by formula II, wherein the method for preparing these salts is simple, the crystal form is easy to control, the stability and solubility are good, and the salts are suitable for preparing a variety of preparations. The present invention also relates to the method for preparing these salts, pharmaceutical compositions comprising these salts, and the use of these salts in the preparation of medicaments for the prevention and treatment of diseases characterized by adverse thrombus formation in mammals.

The invention discloses a preparation method of copper ion doped anatase titanium dioxide. The preparation process comprises the following steps: 1, adding concentrated sulfuric acid into a titanium tetrachloride aqueous solution, and then adding deionized water to obtain a first crude product; 2, adding an oxalic acid copper solution into the first crude product obtained in the step 1, adjusting the pH value to 7-8 by using ammonia, and washing with deionized water to obtain a secondary crude product; 3, washing the secondary crude product obtained in the step 2 with deionized water to obtain a third crude product; step 4, conducting pump filtration on the third crude product washed in the step 3 to obtain a filter cake, drying the filter cake in an air blast drying box, and conducting vacuum drying to obtain a fourth crude product; and step 5, grinding the forth crude product obtained in the step 4 get into particles, heating, calcining and cooling to room temperature to obtain copper ion doped anatase titanium dioxide. The preparation method provided by the invention has the advantages of simple operation, high controllability, and easiness for industrial popularization and application.

The invention provides a low-emission PP material and a preparation method thereof. The low-emission PP material is prepared from the following components in parts by weight: 50-60 parts of PP, 30-40parts of glass fiber, 2-5 parts of a compatilizer, 3 parts of black masterbatch, 1-5 parts of antibacterial agent and 0.2 part of an antioxidant through a double-screw extruder; the TVOC content of the low-emission PP material is less than 50 [mu] gC/g, and the odor is less than grade 4. According to the low-emission PP material and the preparation method thereof, the synergistic effect of all thecomponents in the formula achieves the low-emission effect, the added antibacterial agent nano magnesium oxide and nano zinc oxide mixture plays an unexpected role in effectively reducing the odor and TVOC of the PP material, the preparation method of the low-emission PP material is simple, the used equipment is a common water brace double-screw extruder, and large-scale production is easily realized.

A recovery process for preparing calcium sulfate by utilizing carbide slag is provided. The process includes (1) adding a polymer surfactant into hot water and then adding the carbide slag into the mixture; (2) performing filtration with filter paper; (3) performing filtration with an ultrafiltration membrane; (4) performing degassing treatment by utilizing an ultrasonic instrument and a vacuum pump; (5) adding a saturated sodium chloride solution to precipitate calcium hydroxide solid; (6) performing a reaction with diluted sulfuric acid to form calcium sulfate; and (7) performing filtration and drying the calcium sulfate to obtain high-purity calcium sulfate crystals. The process is advantageous in that the polymer surfactant is added and ensures a stable colloid state of the calcium hydroxide; solid particle impurities such as ferrosilicon and coke are removed through filtration with the filter paper so that a product has good color; the polymer surfactant is removed through filtration with the ultrafiltration membrane; the product is free of odor through degassing treatment; and through adding the saturated sodium chloride solution, the calcium hydroxide solid is precipitated rapidly, a prepared calcium sulfate product has a single crystal form, regular shapes, uniform granularity and a high purity.

The invention belongs to the field of preparation of semiconductor nano-materials, particularly relates to a method for rapidly preparing spherical mercury sulfide nanoparticles, and provides the following scheme aiming at the problems that energy and time cannot be saved and mercury sulfide nano-particles with uniform shape and size and good dispersity cannot be synthesized in the prior art. Themethod comprises the following steps: S1, preparing a reaction mixed solution, namely adding 0.5 mmol of mercury nitrate, 0.5 mmol of sulfur powder and 0.15 g of polyvinylpyrrolidone into 500g of ethylene glycol at room temperature to prepare the mixed solution; S2, synthesis of mercury sulfide nanoparticles: transferring the mixed solution into an oil bath pot containing simethicone, and performing magnetic stirring to enable the mixed solution to react for 2 hours; and S3, separating the mercury sulfide nanoparticles: taking out the mixed solution from the bath pot, adding ultrapure water with the same volume as the mixed solution, centrifuging for 15 minutes, removing the supernatant, reserving the precipitate, washing the precipitate with the ultrapure water, and freeze-drying the precipitate to obtain the spherical mercury sulfide nanoparticles. A solvothermal synthesis system adopted by the invention can be used for preparing spherical nano mercury sulfide; the obtained sphericalmercury sulfide nanoparticles are single in crystal form, good in dispersity, uniform in shape and high in stability; the method and the technological process are simple, short in time consumption, low in reaction temperature and low in energy consumption; the raw materials are low in cost, easy to obtain and beneficial to industrial production.

The invention relates to a preparation method of transition metal phosphide with good morphology, which is simple in process, and eliminates high temperature and high pressure complicated steps. The method comprises the following steps: taking a precursor of cobalt or nickel, and a precursor of phosphorus according to the molar ratio of (1:1)-(1:6); grinding and mixing the precursors uniformly; reacting for 60-240 minutes at 250-800 DEG C under the argon protection condition; porphyrizing the obtained product; using distilled water and absolute ethyl alcohol to respectively wash the product for three times; then drying the washed product at 60-80 DEG C for 12-24 hours, so as to obtain the product CoP or Ni2P. The main raw materials for the method are rich in sources and low in price, so that the cost is low; the synthetic method is novel, the process is simple, and the high temperature and high pressure complicated steps are not required, so as to simplify the preparation procedures and reduce the energy consumption; the prepared CoP and Ni2P are good in morphology, good in crystallization property, and have single crystal forms; the method disclosed by the invention cannot cause environment pollution during the preparation process, and is suitable for large-scale production.

The invention provides a preparation method of imatinib mesylate alpha crystal form. The preparation method comprises the following steps: adding imatinib base to dimethyl sulphoxide, heating for full dissolving, adding methanesulfonic acid for a reaction, adding imatinib mesylate of alpha crystal form as an initiation seed, and adding an alcohol solvent to obtain crystalline imatinib mesylate of the alpha crystal form. The imatinib mesylate of the alpha crystal form obtained through the preparation method has the characteristics of single crystal form, simple operation, stable technology, solving of a solvent residual problem, and high quality, and can completely satisfy demands of medicinal preparations.