Multichannel synchronous real-time digitalized photoacoustic imaging device and method

Abstract

The invention discloses a multichannel synchronous real-time digitalized photoacoustic imaging device and method. The multichannel synchronous real-time digitalized photoacoustic imaging device comprises a laser, a multi-element ultrasonic detector, a front amplification circuit and a data imaging processing unit, wherein the data imaging processing unit comprises a plurality of field programmable gate array (FPGA) acquisition cards, a clock synchronous board card, a programmable communication interface (PCI) extensions for instrumentation express (PXIe) backboard and a central processing unit (CPU) board card, and can be used for realizing acquisition processing for at least 32 paths of synchronous photoacoustic signals. The multichannel synchronous real-time digitalized photoacoustic imaging method comprises the following steps that: the multi-element ultrasonic detector receives the photoacoustic signals produced by laser irradiation on a biological tissue, amplifies the photoacoustic signals and respectively transmits the signals to the FPGA acquisition cards; and each FPGA acquisition card performs preprocessing, deconvolution, continuous wavelet transformation and photoacoustic attenuation compensation on the signals, then transmits the signals to another FPGA acquisition card in a peer-to-peer (P2P) manner, performs imaging processing by adopting a 2-D (two-dimensional) filtration back-projection algorithm, and finally transmits the structure to an upper computer. The method is finished on an FPGA processor; according to a modular design, the expansion of the large-scale detector is simplified; and the device and the method are favorable for clinical application of photoacoustic imaging systems.

Description

technical field [0001] The invention relates to the field of photoacoustic imaging research, in particular to a multi-channel synchronous real-time digital photoacoustic imaging device and method. Background technique [0002] At present, photoacoustic imaging has become a hot spot in the research of medical imaging technology. Photoacoustic imaging is a non-ionizing and non-invasive non-destructive testing technology, which can reflect the structural characteristics, metabolic state and lesion characteristics of biological tissues. It combines the advantages of pure optical imaging and ultrasound imaging to obtain high-resolution and high-contrast biological tissue structure and functional imaging. Moreover, photoacoustic imaging can be easily combined with ultrasound imaging to provide multifunctional imaging diagnosis. [0003] The photoacoustic imaging system has gone through the design process of unit acquisition, multi-phase control acquisition, multi-channel switchin...

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Problems solved by technology

This method is easy to operate and relatively simple to control. It adopts multi-beam synthesis, improves resolution and signal-to-noise ratio, and can realize tomographic imaging, but there are still some shortcomings: 1. The imaging algorithm is completed in the host computer, which greatly reduces the computer 2. Due to the use of independent boards for acquisition and processing, there is no communication capability between boards, so it is impossible to complete multi-channel board expansion. For large-scale multi-channel ( At least 256 channels) acquisition and processing can only take the way of array element switching, which greatly reduces the processing speed of imaging

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