Novel application of malus asiatica composition preparation in preparation of medicine for resisting gynecological malignant tumors

A malignant tumor and composition technology, applied in the direction of antineoplastic drugs, drug combinations, antipyretics, etc., to achieve pain relief, low cost, and improve the quality of life

Pending Publication Date: 2020-09-22
广西壮族自治区花红药业集团股份公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] At present, there is no literature at home and abroad to report that the preparation of the bonus composition is used in the treatment of gynecological malignancies.

Method used

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  • Novel application of malus asiatica composition preparation in preparation of medicine for resisting gynecological malignant tumors
  • Novel application of malus asiatica composition preparation in preparation of medicine for resisting gynecological malignant tumors
  • Novel application of malus asiatica composition preparation in preparation of medicine for resisting gynecological malignant tumors

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] 1. Composition of raw materials: 1250g of red dianthus, 750g of Hedyotis diffusa, 1250g of Peach Blossom, 750g of white back leaf root, 750g of scorpion, 1000g of Miltonia Spatholobus, 1250g of myrtle root, 10g of hydroxypropyl methylcellulose, talcum powder 20g, magnesium stearate 10g, silicon dioxide 130g

[0024] 2. Preparation method: Take a little red, 300g of a little red, grind it into a fine powder, and mix the remaining little red with the rest Hedyotis diffusa and other six flavors are decocted twice with water, the first time is 2 hours, the second time is 1.5 hours, the decoction liquid is combined, filtered, and the filtrate is concentrated to a clear paste with a relative density of 1.18-1.23 (80°C). Add ethanol until the alcohol content reaches 65%, stir well, let it stand for 24 hours, filter, recover ethanol from the filtrate under reduced pressure and concentrate to a thick paste with a relative density of 1.25-1.30 (80°C), dry, grind into fine powder,...

Embodiment 2

[0026] 1. Composition of raw materials: 1667g of a little red, 1000g of Hedyotis diffusa, 1667g of Peach Blossom, 1000g of white back leaf root, 1000g of 菥蓂, 1333g of Caulis Spatholobus, 1667g of myrtle root, 120g of starch, 20g of microcrystalline cellulose, hard Magnesium fatty acid 20g.

[0027] 2. Preparation method: add water to extract two medicinal materials including a little red, Hedyotis diffusa, Peach Blossom, white back leaf root, 菥蓂, myrtle root, and Caulis Spatholobus, the first time is 2 hours, and the second time is 1.5 hours, combine the decoction liquid, filter, concentrate the filtrate to a clear paste with a relative density of 1.18-1.23 (80°C), add ethanol until the alcohol content reaches 65%, stir well, let stand for 24 hours, filter, and decompress the filtrate The ethanol is recovered and concentrated to a thick paste with a relative density of 1.20-1.25 (60°C), spray-dried and granulated, packed into capsules, and made into 1000 granules.

Embodiment 3

[0029] 1. Composition of raw materials: 5000g of red dianthus, 3000g of Hedyotis diffusa, 5000g of Peach Blossom, 3000g of Hedyotis japonicus, 3000g of Spathiphyllum, 4000g of Miltonia Spatholobus, 5000g of myrtle root, 3580g of soluble starch, and 20g of stevia.

[0030] 2. Preparation method: a total of seven medicinal materials including a little red, hedyotis diffusa, ground peach blossom, white back leaf root, scorpion, myrtle root, and spathula, add water and boil twice, the first time for 2 hours, and the second time After 1.5 hours, combine the decoction, filter, concentrate the filtrate to a relative density of 1.20 (80°C), add ethanol until the alcohol content reaches 65%, stir well, let stand for 24 hours, filter, and recover the ethanol from the filtrate under reduced pressure. Concentrate to a thick paste with a relative density of 1.25-1.30 (80°C), add appropriate amount of soluble starch and stevia, mix well, make granules, dry, and pack into 1000 bags.

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Abstract

The invention relates to the technical field of traditional Chinese medicines, and provides new application of a malus asiatica composition preparation in preparation of a medicine for resisting gynecological malignant tumors. The composition is prepared from the following medicines in parts by weight: 1000 to 5000 parts of emilia sonchifolia, 500 to 6600 parts of oldenlandia diffusa, 1000 to 5000parts of Urena lobata, 500 to 6600 parts of mallotus apelta root, 500 to 6600 parts of thlaspi arvense, 1000 to 7500 parts of caulis spatholobi and 1000 to 5000 parts of rhodomyrtus tomentosa root. The Chinese patent medicine malus asiatica composition preparation has a good inhibiting effect on various gynecological malignant tumor cells, a theoretical basis is provided for new application of old medicines, and a new idea is provided for developing the anticancer effect of the malus asiatica composition.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to the new application of a flower red composition preparation in the preparation of anti-gynecological malignant tumor drugs. Background technique [0002] Huahong composition preparation is a kind of Chinese patent medicine, the main ingredients include a little red, Hedyotis diffusa, Peach Blossom, white back leaf root, scorpion, Mildew Spatholobus and myrtle root. The effect of dispelling blood stasis and relieving pain is used for leukorrhagia and irregular menstruation caused by damp heat and stagnation. Symptoms include profuse leukorrhea, thick yellow color, dull pain in the lower abdomen, lumbosacral pain, and abdominal pain during menstruation; chronic pelvic inflammatory disease, adnexitis , Endometritis see the above syndrome. [0003] A little red, the dry whole herb of Emilia sonchifolia (L.) DC. (Source: "Guangxi Zhuang Autonomous Region Zhuang M...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/748A61P35/00A61P35/04A61P29/00A61P25/00
CPCA61K36/28A61K36/748A61K36/185A61K36/47A61K36/31A61K36/486A61K36/61A61P35/00A61P35/04A61P29/00A61P25/00A61K2300/00
Inventor 韦飞燕张艳华刘春明韦金燕唐满姣张伟
Owner 广西壮族自治区花红药业集团股份公司
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