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Oral immune globulin preparation and its preparing process

An immunoglobulin and preparation technology, which is applied in pharmaceutical formulations, medical preparations containing active ingredients, antibodies, etc., can solve the problems that animal milk cannot be directly eaten, biological activity cannot be guaranteed, and has not been successful, and achieves human immune function. Enhancement, rigorous and scientific production process, and the effect of improving immunity

Inactive Publication Date: 2003-08-06
江苏华冠生物技术股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

The latest reports at home and abroad inject vaccines on female animals so that the breast milk produced by them contains immune active substances, but because animal milk cannot be eaten directly and needs to be heated, its biological activity cannot be guaranteed, so the research has not yet been successful

Method used

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Examples

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Embodiment Construction

[0008] The following is a further detailed description of the embodiment of the present invention. Collect the bovine colostrum on the first day after delivery of the cow, transport it to the processing workshop in a 4°C sterile insulated barrel, and pour the bovine colostrum into a high-speed centrifuge at a working environment of 4°C. , set the speed of the centrifuge to 10,000 rpm, run for 12 minutes, remove the upper fat layer, take the lower part of the mixed solution and put it in a fine filter for ultrafiltration with a pore size of 20 μm, and then take the filtrate and put it in a membrane filter Filtrate in a medium filter with a filter pore size of 0.22 μm. Take the filtrate and put it into a vacuum freeze dryer at a freezing temperature of -30°C to make a light milky yellow fine scale-like freeze-dried powder. Grind it into a solute dry powder. Part content is 3-5%, the content of immunoglobulin is 33% by weight of preparation, the content of secretory immunoglobulin...

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Abstract

Colostrum secreted by health cow in the 1-3 day after calving as material is treated through centrifugal defatting, ultrafiltering and vacuum freezing drying in low temperature bacteria-free condition to produce soluble dry powder with immune globulin content of 16-36 wt%. The preparation of the present invention has strong immunity regulating function and is one kind of safe and convenient oral preparation easy to be absorbed by human body. It is suitable for children and adults and has the effects of strengthening body's immunity and raising body's disease ability.

Description

technical field [0001] The invention relates to an oral immunoglobulin preparation and a preparation method thereof, belonging to the technical field of biological health care products. Background technique [0002] Immunoglobulin, referred to as Ig, can neutralize bacterial exotoxins and pathogenic particles, and make the virus lose the ability to continue to infect human cells. It can also inhibit the reproduction of pathogenic microorganisms, block the adhesion of pathogenic microorganisms and membranous cells, and reduce Infection of the human body by foreign bacteria. When the Ig content in the body decreases or is insufficient, it will give foreign viruses, cells and other harmful microorganisms the opportunity to multiply and cause various diseases. Ig can monitor the senescent cells and tumor cells in the human body, so as to maintain the physiological balance of the human body. If the immune function is out of balance, the human body will produce a series of disea...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K35/20A61K39/395A61P37/02
Inventor 李华白华朱宝山
Owner 江苏华冠生物技术股份有限公司
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