Clinical diagnosis and treatment application of acute ischemic stroke based on cerebral microhemorrhage detection

Abstract

The invention discloses clinical diagnosis and treatment application of acute ischemic stroke based on cerebral microhemorrhage detection. The application comprises: selection of a research object, which specifically comprises the following steps: continuously selecting acute ischemic stroke patients hospitalized and treated in the neurology department of the second affiliated hospital of the Xuzhou Medical University from October 2016 to February 2017 as the research object by adopting a prospective research design, collecting and sorting clinical data such as demographic statistics, vascularrisk factors, imaging examination, laboratory examination and treatment modes of patients, and dividing the patients into a CMBs group and a CMBs-free group according to whether the patients are accompanied by CMBs or not; when follow-up visit is carried out for 6 months after attack, dividing the patients in the CMBs group and the patients in the CMBs-free group into a subgroup with poor prognosis (mRS score=2) and a subgroup with good prognosis (mRS score is 0-2) according to an improved Rankin scale (mRS) score; applying single-factor analysis and multi-factor Logistic regression analysisto screen out influence factors of poor prognosis of the patient.

Description

Technical field [0001] The present invention relates to the field of products related to clinical diagnosis and treatment, in particular to the clinical diagnosis and treatment application of acute ischemic stroke based on cerebral microhemorrhage detection. Background technique [0002] With the deepening of the understanding that "time is the brain", stroke has now been recognized as a clinical emergency. Among them, ischemic stroke is the most common type of stroke. Its fatality rate and disability rate are extremely high. Cerebral microbleeds (CMBs) is a subclinical damage to the brain parenchyma characterized by microbleeding, and its cause is still unclear. Histologically, severe hyaluronic acid-like or amyloid changes in the involved microvessels can be seen, or aneurysms of arteriosclerotic microvessels are ruptured [21. In recent years, studies have found that CMBs are the biological signs of central nervous system vascular diseases, and are closely related to symptom...

AI Technical Summary

Problems solved by technology

Although there is no shortage of studies on the correlation between CMBs and the prognosis of acute ischemic stroke, there is still no consensus on the relationship between CMBs and hemorrhagic transformation after treatment of ischemic stroke, and most of these studies are retrospective studies , the sample size is small, especially there is no in-depth analysis of the correlation between the number of CMBs lesions, lesion distribution and prognosis, so we propose the clinical application of acute ischemic stroke based on the detection of cerebral microbleeds

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