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Smear self-inspection method of bone marrow cell morphology automatic detection system

An automatic detection, bone marrow cell technology, used in optical testing flaws/defects, measuring devices, scientific instruments, etc., can solve problems such as whether the smear is representative or whether the smear sample production meets the standard self-inspection, etc.

Active Publication Date: 2020-10-20
THE SECOND AFFILIATED HOSPITAL ARMY MEDICAL UNIV
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  • Abstract
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  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In order to solve the problem that the existing detection system and device about the morphology of bone marrow cells cannot self-check whether the smear is representative or whether the smear sample meets the standard, the invention proposes a method that can detect the representative smear sample. smear self-examination method

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  • Smear self-inspection method of bone marrow cell morphology automatic detection system
  • Smear self-inspection method of bone marrow cell morphology automatic detection system
  • Smear self-inspection method of bone marrow cell morphology automatic detection system

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Embodiment Construction

[0023] A smear self-inspection method of a bone marrow cell morphology automatic detection system, comprising the following steps: S1: scanning the smear, performing basic image judgment and correction, and forming images with different magnifications. S2: Identify the obvious traces on the image and judge the standardization of smear making. S3: Further identify the image and determine the representativeness of the sample. S4: Enter the statistical counting work.

[0024] S1 includes the following steps: A1: scanning the smear to form images of different magnifications. A2: Determine whether there is a problem with the observation target in the image or whether there is an afterimage in the image. If yes, go to A4; if not, go to A3. A3: Determine the brightness of the image, if it is too bright or too dark, go to A5, if not, go to S2. A4: If there is a problem with the observation target or afterimage, re-scan and skip to A2. A5: If it is too bright or too dark and it is ...

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Abstract

The invention belongs to the field of bone marrow cell morphology detection, and particularly relates to a smear self-detection method of a bone marrow cell morphology automatic detection system. According to the technical scheme, the smear self-inspection method of the bone marrow cell morphology automatic detection system comprises the following steps of S1, scanning smears, conducting basic image judgment and correction, and forming images with different magnification times; S2, identifying an obvious trace on the images, and judging the standard of smear making; S3, further identifying theimages, and judging the representativeness of a sample; S4, entering statistical counting work. Whether a smear has representativeness or not is self-inspected by performing proper counting area screening on a scanned image of the smear and calculating the area ratio of the counting observation area to the removed area. Whether manufacturing of the smear meets the standard or not is self-inspected by detecting whether fingerprints, bubbles and impurities exist on the scanned image or not.

Description

technical field [0001] The invention belongs to the field of bone marrow cell morphology detection, and specifically relates to a smear self-test method of a bone marrow cell morphology automatic detection system. Background technique [0002] Microscopic examination of bone marrow cell morphology is one of the key diagnostic methods in hematology and is commonly used to diagnose a variety of diseases, including leukemia, multiple myeloma, lymphoma, anemia and pancytopenia. According to the "Guidelines for the Diagnosis of Myeloid Malignant Tumors" issued by the World Health Organization, detailed and precise microscopic manual examination is required for diagnosis. Normal bone marrow contains differentiated cells at all stages of development, from early precursor stem cells to functionally mature cells, including hematopoietic stem cells, which are precursors to most blood cells, and mesenchymal and endothelial stem cells, which are considered the gatekeeper cells of the bo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/88G01B11/28
CPCG01N21/8851G01B11/28G01N2021/8887Y02A90/10
Inventor 彭贤贵张曦杨武晨张诚张洪洋墙星张云李艺陈思宇
Owner THE SECOND AFFILIATED HOSPITAL ARMY MEDICAL UNIV
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