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Silver ion disinfection gel and preparation method thereof.

A technology of disinfecting gel and silver ions, applied in the field of medicine, can solve the problems of inability to promote wound healing, long wound healing time, poor sterilization effect, etc., to improve bioavailability, avoid uneven sterilization, and fast sterilization time. Effect

Active Publication Date: 2020-10-27
ANSON NANO BIOTECH ZHUHAI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main function of this medical dressing loaded with nano-silver and bioactive factors is antibacterial, but it cannot promote wound healing
[0006] In summary, there are technical defects such as poor sterilization effect, long wound healing time, easy wound infection, and easy secondary injury in the prior art.

Method used

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  • Silver ion disinfection gel and preparation method thereof.
  • Silver ion disinfection gel and preparation method thereof.
  • Silver ion disinfection gel and preparation method thereof.

Examples

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preparation example Construction

[0033] The preparation method of silver ion disinfection gel described in the present embodiment specifically comprises the following steps:

[0034] S1. Mix sodium alginate and nano-silver oxide, put them in a disc grinder, and grind them for 0.5h at a rotating speed of 400rpm to obtain a mixed powder;

[0035] S2. Mix gelatin, coupling agent and sorbic acid, stir evenly, place at 3°C ​​for 2 hours, add sodium sulfate and water, stir evenly, and stand at 25°C for 3 days to obtain a hydrogel ;

[0036] S3. Add the mixed powder prepared in step S1, bacteriostatic agent, humectant and Kakadu plum extract to the hydrogel prepared in step S2, stir evenly and homogenize for 2 hours, and the product is obtained.

Embodiment 1

[0037] Embodiment 1, a kind of silver ion disinfection gel

[0038] The silver ion disinfection gel comprises the following components and parts by weight: 14 parts of sodium alginate, 2 parts of nano-silver oxide, 40 parts of gelatin, 15 parts of coupling agent, 25 parts of sorbic acid, 10 parts of sodium sulfate, antibacterial 20 parts of moisturizing agent, 5 parts of moisturizing agent, 5 parts of Kakadu plum extract, 50 parts of water.

[0039] The particle size of the nano-silver oxide in the silver ion disinfection gel is 5-75nm.

[0040] The coupling agent in the silver ion disinfection gel consists of vinyltriethoxysilane, chloromethyltriethoxysilane and β-(3,4-epoxycyclohexyl) ethyltrimethoxysilane by mass The ratio is 9:3:1 composition.

[0041] The antibacterial agent in the silver ion disinfection gel is composed of camellia polysaccharide, benzalkonium chloride and clove essential oil in a mass ratio of 9:4:11.

[0042] The moisturizing agent in the silver ion d...

Embodiment 2

[0044] Embodiment 2, a kind of silver ion disinfection gel

[0045] The silver ion disinfection gel comprises the following components and parts by weight: 23 parts of sodium alginate, 8 parts of nano-silver oxide, 43 parts of gelatin, 31 parts of coupling agent, 30 parts of sorbic acid, 20 parts of sodium sulfate, antibacterial 25 parts of moisturizing agent, 15 parts of moisturizing agent, 6 parts of Kakadu plum extract, 55 parts of water.

[0046] The particle size of the nano-silver oxide in the silver ion disinfection gel is 20-75nm.

[0047] The coupling agent in the silver ion disinfection gel consists of vinyltriethoxysilane, chloromethyltriethoxysilane and β-(3,4-epoxycyclohexyl) ethyltrimethoxysilane by mass The ratio is 11:7:5 composition.

[0048] The antibacterial agent in the silver ion disinfection gel is composed of camellia polysaccharide, benzalkonium chloride and clove essential oil in a mass ratio of 13:7:16.

[0049] The moisturizing agent in the silver...

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Abstract

The invention belongs to the field of medicines, and particularly relates to silver ion disinfection gel and a preparation method thereof. The silver ion disinfection gel provided by the invention isprepared from sodium alginate, nano silver oxide, gelatin, a coupling agent, sorbic acid, sodium sulfate, a bacteriostatic agent, a humectant, a Kakadu Plum extract and water. The silver ion disinfection gel provided by the invention is high in air permeability, can effectively sterilize within 4 minutes, and can durably keep long-acting sterilization on the surface of a wound, so that the healingspeed of the wound is accelerated. Besides, the silver ion disinfection gel provided by the invention takes the sodium alginate spherical capsule as a carrier of silver ions to form gel, and the release rate of the silver ions is effectively controlled, so that a rapid and uniform sterilization effect is achieved.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a silver ion disinfection gel and a preparation method thereof. Background technique [0002] At present, medical institutions use iodine to disinfect the wounds, and then apply ordinary dressings or functional dressings to the surface for wound treatment. However, disinfectants such as iodine, hydrogen peroxide, and alcohol are irritating when they are quickly disinfected, and the patient feels that the wound pain is aggravated, and the sterilization duration of the above disinfectants is short and has no long-term effect. Reapplying ordinary dressings or functional dressings takes a certain amount of time to make the wound heal. [0003] Dressings can improve the microenvironment of wounds and play a vital role in wound healing. An ideal wound dressing should have the characteristics of non-toxicity, good biocompatibility, acceleration of wound healing, and prevention of wo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00
CPCA61L26/0004A61L26/0023A61L26/0038A61L26/0057A61L26/0066A61L26/008A61L2300/208A61L2300/232A61L2300/30A61L2300/404A61L2300/45C08L5/04C08L89/00
Inventor 周家发史廷龙
Owner ANSON NANO BIOTECH ZHUHAI
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