1403 results about "Sulphate sodium" patented technology

The invention relates to the field of environmental remediation, and discloses a remediation method for high-concentration organic pollutants in soil, which comprises the following steps: firstly, injecting a nano zero-valent iron (nZVI) suspension into the contaminated soil for chemical reduction treatment, then adding sodium persulfate for oxidation treatment, and then adding a nano zero-valent iron (nZVI) suspension into the contaminated soil; the complex organic pollutants are converted into biodegradable intermediate products; then, two-stage microbial communities are introduced in sequence, the first-stage microbial community is used for degrading alcohol and ketone intermediate products, the second-stage microbial community is used for degrading organic acid intermediate products, and thorough mineralization of pollutants is achieved. According to the method, the pollutant degradation rate and the final removal effect can be remarkably improved, and the method is suitable for treatment scenes of various high-concentration organic pollutants and has high adaptability and economic benefits.

The invention discloses a method for recovering lithium phosphate from lithium iron phosphate black powder. The method comprises the following steps: mixing black powder recovered from waste lithium iron phosphate batteries with sodium persulfate, and calcining; adding water into the obtained calcined product, dissolving, filtering to obtain water extract A and leaching residues, washing the leaching residues with water, and calcining at high temperature to obtain battery-grade iron phosphate; adding a sodium hydroxide solution into the water extract A, and reacting to obtain a water extract B; adding a trisodium phosphate solution into the water immersion liquid B, fully reacting, performing suction filtration to obtain lithium phosphate and filtrate, and cleaning and drying the lithium phosphate to obtain battery-grade lithium phosphate; and freezing and denitrifying the filtrate to obtain a denitrified solution, and adding the denitrified solution into the sodium hydroxide solution for recycling. The method does not generate wastes, recycles the filtrate in the whole process, theoretically realizes zero loss of the lithium element, prevents the iron element from entering the solution, simplifies the preparation steps of the lithium phosphate, and has the advantages of cost reduction and environmental protection.

The invention provides a melogabalin besylate tablet and a preparation method thereof, the melogabalin besylate tablet comprises a plain tablet and a coating, the plain tablet comprises, by mass, 4.39% of melogabalin besylate, 75-85% of mannitol 150SD, 3-10% of a disintegrating agent, 0.5-3% of a lubricant, 0.1-0.5% of an adsorbent, 1-10% of a filler, 0.5-3% of an antioxidant A and 0.1-3% of an antioxidant B; and the coating comprises the following components in percentage by mass: 30-45% of talcum powder, 2-10% of lauryl sodium sulfate, 30-45% of glycerol monocaprylate / dicaprylate, 2-10% of titanium dioxide, 30-45% of polyvinyl alcohol, 0.5-2% of iron oxide yellow and 0.5-2% of iron oxide red. The melogabalin besylate tablet prepared by the invention uses specific coating composition and specific coating parameters, so that the melogabalin besylate tablet can be stably stored without a drying agent and a composite aluminum bag for medicine packaging, the stability of the tablet is greatly improved, the complexity of equipment required by production is simplified, and the production cost is greatly saved.

The invention relates to a high-antistatic crude oil type polyester FDY spinning oil agent and a preparation method thereof, a composition of sodium lauryl polyoxyethylene ether sulfate and potassium lauryl phosphate is used as a main antistatic agent, an antistatic smoothing agent with sulfonated chitosan and PEG800 as key components is adopted, the antistatic smoothing agent and the main antistatic agent have a synergistic effect, and the antistatic property of the spinning oil agent is improved. The overall antistatic property of the oiling agent is enhanced. The preparation method comprises the following steps: pre-balancing the materials at 40-50 DEG C before charging; then, sequentially adding an antistatic smoothing agent, a penetrating agent, a bundling agent, a main antistatic agent and an anti-coking agent, and adding materials while stirring; and finally, controlling the temperature of the reaction kettle to be 40-50 DEG C and the stirring speed to be 500-700r / min, and reacting for 0.5-1.5 hours. The crude oil type polyester FDY oiling agent is excellent in antistatic property, and polyester FDY spinning can be carried out in a crude oil direct oiling mode at the ultrahigh spinning speed of 4000 m / min.

A low-carbon near zero emission process of industrial waste water, comprising: S1: entering industrial waste water into a pre-oxidation system to improve biodegradability of organics; S2: after treatment in the pre-oxidation unit, entering the waste water into an anaerobic biological treatment system, sodium chloride and sulfate is deeply removed and carbon sources in the waste water can be used to remove the sulfate and nitrate; S3: entering water output from the anaerobic biological treatment system into a membrane concentration system and membrane concentrated solution enters a nano-filtration salt fractionation system for salt fractionation; and S4: refluxing nano-filtration concentrate solution generated by the nano-filtration salt fractionation system to the anaerobic biologic treatment system for biological desulfurization, or synthesizing the nano-filtration concentrate solution to be sodium persulfate by electro chemical methods, and refluxing proportionately to a waste water pre-oxidation system for use in-situ.

The invention discloses a strain of lactobacillus pentosus JNL0030, application thereof and a microbial preparation, and belongs to the technical field of microorganisms. The lactobacillus pentosus JNL0030 is preserved in the China General Microbiological Culture Collection Center on June 24, 2024, the preservation address is No.3, No.1 yard, Beichen West Road, Chaoyang District, Beijing, the preservation number is CGMCC (China General Microbiological Culture Collection Center) NO: 31045, and the lactobacillus pentosus is classified and named as lactobacillus pentosus. The strain can realize high yield of indole-3-lactic acid in an MRS culture medium. An in-vitro experiment result shows that supernate of the strain remarkably inhibits inflammatory polarization of macrophages stimulated by lipopolysaccharide and secretion of inflammatory factors. Animal experiment results show that the strain can significantly inhibit sodium dextran sulfate induced colonic tissue inflammatory factor secretion and intestinal barrier injury, alleviate ulcerative colitis, and show a huge application value.

This application discloses a detergent tablet free of SLS surfactant and its preparation method. The detergent tablet includes a film-forming agent, an anionic surfactant, a non-ionic surfactant, a chelating agent, an enzyme preparation, an auxiliary agent and a essence. The film-forming agent includes one or more of polyvinyl alcohol, cellulose, and dodecenyl succinate starch ester. The anionic surfactant includes at least two of sodium α-olefin sulfonate, sodium fatty acid methyl ester sulfonate, and sodium hydroxyethyl sulfonate. The non-ionic surfactant includes at least two of fatty alcohol polyoxyethylene ethers, fatty acid methyl ester ethoxylate, and oil ethoxylate.

The invention discloses a coloring agent for an organic silicon product and a preparation method of the coloring agent, and belongs to the technical field of fine chemical engineering, and the coloring agent is characterized by being prepared from the following raw materials in parts by weight: 40 to 60 parts of inorganic pigment, 30 to 50 parts of silicone oil and 2 to 7 parts of dispersing agent; the dispersing agent comprises modified sodium alginate and lauryl sodium sulfate in a weight ratio of 1: (0.5-1.2), and the effects of solving the problems that the inorganic pigment is easy to form aggregates and poor in coloring effect are achieved.

The invention relates to a method for extracting high-purity astragalus polysaccharide. The method comprises the following specific steps: washing astragalus, drying and crushing into coarse powder; under a certain solid-liquid ratio, extracting astragalus polysaccharide by using ultrasonic waves; carrying out mixed enzymolysis on the extracting solution and cellulase, and terminating enzyme reaction through heating; and mixing the enzymatic hydrolysate with specific molecularly imprinted polymers (MIPs), specifically adsorbing the astragalus polysaccharide through a molecular recognition effect, and eluting and purifying by using a mixed solution of water and ethanol. In the preparation process of the MIPs, oligosaccharide fragments of astragalus polysaccharide, acrylamide, ethylene glycol dimethacrylate, potassium persulfate and lauryl sodium sulfate are dissolved in methanol, and free radical polymerization reaction is carried out under the protection of nitrogen. Experimental results show that the purity and the extraction rate of the astragalus polysaccharide extracted by the method are remarkably improved, and the method has the advantages of simplicity and convenience in operation, high efficiency, economy, environmental protection and the like.

According to the environment-friendly scale and corrosion inhibitor for the green treatment of the circulating cooling water of the thermal power plant, the polyepoxysuccinate copolymer is synthesized, itaconic acid, sodium p-styrenesulfonate and sodium epoxysuccinate synthesized by maleic anhydride are adopted as monomers, sodium persulfate is adopted as an initiator, and a terpolymer IA / PESA / SSS is synthesized in a free combination manner; according to the optimal synthesis scheme, the molar ratio of IA to PESA is 4: 1, the molar ratio of PESA to SSS is 1: 4, the use amount of the initiator accounts for 2% of the mass of the monomer, the polymerization temperature is 95 DEG C, and the reaction time is 4 h. A dynamic simulation experiment shows that the copolymer is excellent in scale inhibition performance, and meanwhile, the synthesis evaluation is successful. According to the invention, the concentration ratio of the circulating cooling water is improved, so that the utilization ratio is improved, and the purpose of saving water is achieved; meanwhile, generation of scale substances is reduced, and high heat exchange efficiency is maintained; the corrosion condition of the system is relieved and prevented, safe operation of the system is kept, and safe and stable operation of the system is kept.

The invention relates to the technical field of preparation of an electrolyte for a vanadium redox flow battery, in particular to a reduction method of an alkaline vanadium-containing solution during short-process preparation of a vanadium electrolyte. The reduction method comprises the following steps: (1) adding a reducing agent sodium sulfite into an alkaline vanadium-containing solution and dissolving; and (2) acid is added into the solution obtained after dissolving in the step (1), the pH is adjusted, a reduction reaction is conducted, and vanadium is reduced to be tetravalent. The method provided by the invention effectively solves the problem of vanadium loss caused by precipitation generated in the sequential operation process of acidification and reduction of the alkaline vanadium-containing solution in the prior art, and meanwhile, the method provided by the invention is easy for engineering implementation.

The invention relates to the technical field of medicines, in particular to a compound amlodipine atorvastatin calcium tablet and a production mixing device. The compound amlodipine atorvastatin calcium tablet is a core-coated tablet and comprises an inner-layer tablet core containing atorvastatin calcium and an outer-layer tablet layer containing amlodipine besylate, the inner-layer tablet core further comprises meglumine and sodium lauryl sulfate, the mass ratio of meglumine to sodium lauryl sulfate is (0.5-5): 1, the mass ratio of meglumine to sodium lauryl sulfate is (0.5-5): 1, and the mass ratio of meglumine to sodium lauryl sulfate is (0.5-5): 1. And the mass of the meglumine accounts for 1-3% of the total mass of the inner-layer tablet core. The amlodipine and atorvastatin calcium are prepared into the coated tablet, so that two active ingredients in the same tablet are effectively isolated, and the compatibility of the atorvastatin calcium and the amlodipine besylate is remarkably improved; meanwhile, the inner layer and the outer layer of the core-coated sheet are separately granulated before tabletting, so that the problem that the mixing uniformity of total mixed particles is relatively poor when conventional tablets are prepared is effectively solved.

The invention relates to the technical field of microbial medicines, and particularly discloses Brawler's bacteria EMF75-02B1B and an application of the Brawler's bacteria EMF75-02B1B. The invention discloses Blauria sp. EMF75-02B1B, which is preserved in the Guangdong Microbial Culture Collection Center on September 2, 2024, and the preservation number of the Blauria sp. EMF75-02B1B is GDMCC No: 65084. A mouse model proves that the Brawler bacteria EMF75-02B1B can obviously improve the disease activity index (DAI) of a dextran sodium sulfate induced ulcerative colitis mouse, relieve the weight loss and colon shortening degree of the ulcerative colitis mouse, enhance the intestinal barrier function and relieve inflammatory response.

The invention provides a nano-modified composite gel foam inhibitor for inhibiting spontaneous combustion of coal and a preparation method of the nano-modified composite gel foam inhibitor, and relates to the technical field of preparation of composite inhibitors. The nanometer modified composite gel foam stopping agent is prepared from six components including sodium polyacrylate serving as a gelling agent, konjac glucomannan serving as a cross-linking agent, lauryl sodium sulfate serving as a foaming agent, xanthan gum serving as a foam stabilizer, nanometer silicon dioxide particles and modified antioxidant powder, the optimal proportion of the gelling agent is 2.5 wt%, the optimal proportion of the cross-linking agent is 0.3 wt%, the optimal proportion of the foaming agent is 0.3 wt%, and the optimal proportion of the modified antioxidant powder is 0.3 wt%. The optimal proportion of the foam stabilizer is 0.4 wt%, the optimal proportion of the nano SiO2 particles is 4 wt%, and the optimal proportion of the modified antioxidant is 2 wt%. Different components endow the nano SiO2 modified composite gel foam with different physical and chemical structural characteristics and coal spontaneous combustion prevention performance characteristics, and by adding the nano SiO2 particles and the bentonite modified tert-butylhydroquinone antioxidant, the overall stability and inhibition efficiency of the gel foam are improved.

The invention relates to the technical field of foaming agents, and discloses a high-temperature-resistant foaming agent and a preparation method thereof. The high-temperature-resistant foaming agent is obtained by adding sulphobetaine modified benzoxazine, melamine benzene sulfonate modified polyoxyethylene ether, lauryl sodium sulfate and a polyvinyl alcohol foam stabilizer into water, stirring and mixing. The benzoxazine structure has relatively high rigidity and stability at a high temperature; sulfobetaine is an ampholytic surfactant and has high foaming capacity, sulfonic acid groups are high in temperature resistance, and the foaming performance and the high temperature resistance of the foaming agent are improved; melamine molecules are not easy to decompose at high temperature, so that the high temperature resistance of the foaming agent is improved; polyoxyethylene ether is a nonionic surfactant and has remarkable surface activity, the sulfonic acid group anions and the polyoxyethylene ether nonionic surfactant play a synergistic role, mixed micelles are formed in an aqueous solution, and the foaming performance of the foaming agent is improved.

The invention belongs to the field of recycling treatment of waste lithium iron phosphate batteries, and particularly relates to a method for efficiently recycling waste lithium iron phosphate through oxygen-sodium persulfate leaching. According to the method, the lithium in the lithium iron phosphate waste battery is leached and extracted by adopting the environment-friendly reaction solution, and oxygen is additionally introduced in the extraction process, so that the leaching rate of the lithium is effectively improved, the leaching rate of iron is effectively reduced, and the overall leaching time is effectively shortened; therefore, the problem of secondary pollution to the environment when inorganic acid / alkali is recycled by an existing wet method is avoided, the process is low in cost and easy to implement, the extraction rate is high, and economic benefits of waste LFP battery recycling are considered from multiple aspects.

The invention discloses a method for extracting PN / PDRN from lactobacillus bulgaricus and application of the PN / PDRN in relieving and anti-inflammatory aspects, belongs to the technical field of biochemistry, and solves the problems that in the prior art, the acquisition source of PN / PDRN is unstable, and pollution easily exists. According to the preparation method, cell walls of lactobacillus bulgaricus are preliminarily dissolved through alkaline conditions and lysozyme in the preparation process, cell membranes of bacteria are destroyed through lauryl sodium sulfate to be split, the conditions are mild, meanwhile, PVP is added to protect a PN structure, and the purity of the PN / PDRN is effectively improved through a final product prepared through the preparation method.

The invention provides a composite quality control liquid for an electrochemical multi-parameter detector. The composite quality control liquid comprises a buffer volume, a quality control substance and a stabilizer, the stabilizing agent comprises 5 to 50 g / L of bovine serum albumin, 0.1 to 10 g / L of EDTA-2Na (Ethylene Diamine Tetraacetic Acid), 10 to 100 g / L of a viscosity regulator, 0.3 to 25 g / L of a preservative and 5 to 20 g / L of a surfactant; the preparation method comprises the following steps: adding components of the stabilizer into a buffer system, preparing a preparation solution, preparing mother liquor of each quality control substance, proportionally mixing glucose mother liquor, uric acid mother liquor, beta-hydroxybutyric acid mother liquor and cholesterol sodium sulfate and triglyceride composite mother liquor according to the target concentration of the quality control solution, and fixing the volume by using the preparation solution to obtain the quality control liquid. And fully and uniformly mixing to obtain the composite quality control liquid. The composite quality control liquid can ensure that uric acid is not degraded, cholesterol triglyceride is not separated out, the formula is mild, and active substances in a detection system are not influenced.

The present invention relates to a high antistatic crude oil type polyester FDY spinning finish and its preparation method. The composition of sodium lauryl polyoxyethylene ether sulfate and potassium lauryl phosphate is used as the main antistatic agent, and an antistatic smoothing agent with sulfonated chitosan and PEG800 as key components is adopted. The antistatic smoothing agent and the main antistatic agent act synergistically to enhance the overall antistatic property of the finish. Preparation method: Each material is pre-equilibrated at 40°C to 50°C before feeding; then, the antistatic smoothing agent, penetrant, bundling agent, main antistatic agent, and anti-coking agent are added in sequence while stirring; finally, the temperature of the reaction kettle is controlled at 40°C to 50°C, the stirring speed is 500 to 700 r / min, and the reaction is carried out for 0.5 to 1.5 h. The present invention is a crude oil type polyester FDY finish with excellent antistatic property, and can carry out polyester FDY spinning in the way of directly applying oil with crude oil at a super high spinning speed of 4000 m / min.

The invention belongs to the technical field of biological medicine, and particularly relates to sterile cefepime hydrochloride and a direct preparation method thereof. The method comprises the following steps: firstly, carrying out condensation reaction on a 7-MPCA solution and an AE active ester solution through a solid base catalyst column at the same time; then, carrying out extraction phase separation, two times of pH regulation crystallization, activated carbon decoloration and sodium sulfite reduction on the condensation liquid to obtain a cefepime hydrochloride liquid to be crystallized; and then taking a part of the cefepime hydrochloride to-be-crystallized liquid to prepare a seed crystal mixed liquid, and adding the rest of the cefepime hydrochloride to-be-crystallized liquid and the crystallization solvent into the seed crystal mixed liquid at a specific speed to obtain the sterile cefepime hydrochloride. According to the method disclosed by the invention, the continuous production of the sterile cefepime hydrochloride is realized, the preparation period of the sterile cefepime hydrochloride is greatly shortened, side reactions and product degradation are reduced, the quality and yield of the obtained cefepime hydrochloride product are relatively high and stable, and industrial production is facilitated.

The invention belongs to the technical field of protein content determination, and particularly relates to a method for determining the protein content of corn kernels. The method comprises the following steps: extraction of corn kernel proteins: extracting different types of corn kernel proteins respectively; determining the protein content of the corn kernels: drawing a standard curve by using a bovine serum standard protein solution; calculating to obtain different types of corn kernel proteins; the sum of the contents of the proteins of the different types of corn kernels is the total protein content of the corn kernel sample. According to the method, the protein components in the corn kernel sample are extracted by adopting a sequential extraction method, each protein component can be completely extracted, the use amount of the sample is small, the operation process is simple, the cost is relatively low, and a basis is provided for accurately measuring the content of the protein components in the corn kernels. According to the method, toxic reagents such as concentrated sulfuric acid, lauryl sodium sulfate, phenolic substances and mercaptoethanol are not used, so that the health of operators is not damaged, and the safety in the experiment process is ensured.

A solid gel foam fire extinguishing agent includes a material A and a material B; the material A includes the following components in mass percentage: 18% to 25% of an inorganic silicate, 0.25% of sodium carboxymethyl cellulose, 0.25% of sodium alginate, 0.1% to 0.5% of xanthan gum, 0.5% to 1% of polyvinyl alcohol, 0.5% to 1.5% of sodium lauryl sulfate, 0.01% to 0.05% of dodecanol, 0.005% to 0.01% of disodium ethylenediaminetetraacetate, and water as a balance; and the material B includes the following components in mass percentage: 25% of sodium dihydrogen phosphate, 25% of acetic acid, 1% to 1.5% of fatty alcohol polyoxyethylene ether, 0.1% to 0.5% of 3% aqueous film-forming foam, 0.01% to 0.05% of the dodecanol, and water as a balance. The fire extinguishing agent exhibits advantages including low density, low oil wettability, high resistance, high adhesiveness, and foam collapse-resistant properties in fire resistance.

A method for the bioremediation of hydrocarbon-contaminated production water through the microbiological process of culturing salt-tolerant bacteria in a high-salt cell culture medium for decontamination. The high-salt cell culture medium contains sodium chloride, sodium sulfate, sodium bicarbonate, calcium chloride, and calcium chloride, along with agar, water, and salt-tolerant bacteria to form broth. Once incubated to form an inoculation mixture, this broth is combined with production water to produce a bacteria-containing liquid mixture, and then treated with production water, bioremediating by propagating the bacteria-containing liquid mixture in the treated production water.

A pharmaceutical composition comprising sitagliptin or a pharmaceutically acceptable salt thereof, wherein the composition comprises less than 5 ppm of 7-Nitroso-3-(trifluoromethyl)- 5,6,7,8-tetrahydr

The present invention relates to the field of biomedical materials, and in particular to a method for preparing a decellularized cartilage matrix material derived from pig rib cartilage, comprising the following steps: (1) freezing and thawing the pig rib cartilage for 5 times; (2) soaking the pig rib cartilage frozen and thawed in step (1) in a sodium borohydride solution; (3) soaking the pig rib cartilage treated with sodium borohydride in step (2) in a sodium dodecyl sulfate solution; and (4) enzymolyzing the pig rib cartilage obtained in step (3) with a mixed solution of DNase and RNase. The present invention is suitable for decellularization of cartilage tissue with a thickness of 300 microns, and utilizes the spontaneous generation of hydrogen by the sodium borohydride solution to effectively expand the cartilage tissue, and then the surfactant SDS fully destroys the cell membrane, effectively removes the genetic material, and retains the effective components or extracellular matrix of the natural cartilage to the greatest extent.

The invention discloses a method for preparing a sodium-rich boundary-rich iron-based prussian blue analogue (FePBA) through one-step hydrothermal synthesis assisted by sodium thiosulfate. The method specifically comprises the following steps: preparing a solution A and a Na4Fe (I I) (CN) 6 solution; the molar ratio of ferrocyanide to Fe ions in the solution B is 3: 4. And preparing a solution B to react with ferrocyanide to form FePBA. Adding sodium citrate to form a sodium and citrate-rich environment, then adding ferric iron salt, and fully stirring to chelate the added Fe < 3 + > with the citrate; and adding sodium thiosulfate after the step. Preparing a PVP (Polyvinyl Pyrrolidone) solution to play roles in dispersing FePBA and reducing agglomeration, and taking the PVP solution as a solution C; slowly dropwise adding the solution A and the solution B into the solution C at a constant speed by using a rubber head dropper to finally obtain a precursor solution, carrying out hydrothermal reaction for 6 hours at 110 DEG C, carrying out suction filtration on the obtained precipitate, and drying to obtain a FePBA sample. According to the invention, the time required for synthesis is greatly shortened, and the traditional coprecipitation of more than 24 hours is improved into rapid hydrothermal reaction of 6 hours.

The invention relates to the field of demulsifiers, in particular to an oil sludge demulsifier as well as a preparation method and application thereof. The oil sludge demulsifier comprises the following components in parts by mass: 20-35 parts of a surface active compound, 7-12 parts of a sodium alkyl sulfate cosolvent, 0.6-1.8 parts of a stabilizer and 48-55 parts of water, wherein the surface active compound comprises hyperbranched polyamidoamine and polyether amine modified magnetic nanoparticles. According to the oil sludge demulsifier, the problems that most of existing demulsifiers are small in dehydration amount, low in dehydration speed, poor in demulsification effect and low in treated oil content are solved, the demulsification performance of the oil sludge demulsifier is improved, the demulsification and dehydration efficiency is improved, and effective separation of oil sludge is achieved.

The invention relates to the technical field of polycarboxylic acid water reducer macromonomers, in particular to preparation and application of a low-air-entraining type TPEG polyether macromonomer, and the low-air-entraining type TPEG polyether macromonomer mainly comprises the following components in parts by mass: 10-20 parts of organopolysiloxane, 1-5 parts of an emulsifier, 2-10 parts of a thickener and 60-80 parts of a solvent. The emulsifier is one or a combination of more of sorbitan monostearate, sodium lauryl sulfate, polyoxyethylene ether, polyvinyl alcohol and sorbitan monooleate; the thickening agent is one or a combination of several of carboxymethyl cellulose, sodium polyacrylate, tragacanth, sodium starch phosphate, hydroxypropyl methyl cellulose and sodium alginate; wherein the solvent is water, and the low-air-entraining type TPEG polyether macromonomer disclosed by the invention has the following beneficial effects that the low-air-entraining type TPEG polyether macromonomer researched by the invention is small in adding amount of a defoaming agent, stable, efficient, high in economic benefit, easy to meter and simple and convenient to operate; redundant large bubbles in the concrete can be eliminated, proper small bubbles are reserved, the strength of the concrete is enhanced, and the surface of the concrete is more attractive.

The invention provides a pharmaceutical composition containing fenerenone, which comprises the following components in percentage by weight: 1.0%-30.0% of fenerenone, 1.0%-5.0% of hydroxypropyl methylcellulose, 0.1%-1.0% of lauryl sodium sulfate, 5.0%-15.0% of polyvinylpolypyrrolidone and 0.5%-5.0% of sodium stearyl fumarate. The filler is microcrystalline cellulose and lactose monohydrate, a wet granulation process is adopted, the pharmaceutical composition has the characteristics of stable and rapid dissolution and rapid disintegration of the fenerenone, the process is simple, the production steps are simplified, the production efficiency is improved, and the cost is reduced.

This invention discloses a method for extracting PN / PDRN from Lactobacillus bulgaricus and its application in soothing and anti-inflammatory effects. Belonging to the field of biochemistry, this method solves the problems of unstable PN / PDRN sources and susceptibility to contamination in existing technologies. In this invention, the preparation relies on alkaline conditions and lysozyme to initially dissolve the cell wall of Lactobacillus bulgaricus, and then sodium dodecyl sulfate is used to disrupt the bacterial cell membrane, causing it to lyse. The conditions are mild, and PVP is added to protect the PN structure. The final product prepared by this invention effectively improves the purity of the obtained PN / PDRN.