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Composition for skin wounds

A technology for skin wounds and external compositions, applied in the directions of skin diseases, drug combinations, drug delivery, etc., can solve the problems of requiring surgical treatment, conservative treatment and unable to expect therapeutic effects, and achieve excellent preventive and/or therapeutic effects.

Pending Publication Date: 2021-01-26
SUMITOMO SEIKA CHEM CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, skin ulcers and bedsores are still refractory diseases
[0005] For refractory skin ulcers and decubitus ulcers, the current situation is that conservative treatments using external preparations for wound therapy (patent document 1) such as white sugar / povidone-iodine complexes cannot expect sufficient therapeutic effects in many cases. Surgical treatment (skin grafting, etc.), so it is desired to develop a new skin external preparation that exerts a better therapeutic effect

Method used

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  • Composition for skin wounds
  • Composition for skin wounds
  • Composition for skin wounds

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0082] The present invention will be described more specifically below.

[0083] Preparation of CO-containing compositions 1

[0084] [H 2 O+CO sample preparation method]

[0085] 2.5 mL of pure water was added to a vial (manufactured by Maruemu Co., Ltd., 3 mL), and it was sealed with a rubber stopper and an aluminum seal. Then, gas with any CO concentration (the balance is N 2 ). Using a gas-tight syringe (MS-GAN500 manufactured by Ito Seisakusho Co., Ltd.), the gas phase part in the vial was replaced with the gas in the Tedlar bag so that the pressure was about 2 atmospheres. Then, it was left to stand until the CO in the gas phase was dissolved in the liquid phase to reach an equilibrium state.

[0086] Table 1 shows the CO concentration in the obtained CO-containing composition (water is a solvent). In addition, the CO concentration in a composition was analyzed by the gas chromatography (GC-2014, FID manufactured by Shimadzu Corporation).

[0087] [Table 1]

[00...

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Abstract

Provided The present invention provides a means that can be used to treat skin wounds. Specifically, the present invention provides a composition for preventing and / or treating skin wounds that contains carbon monoxide.

Description

technical field [0001] The present invention relates to compositions and the like for preventing and / or treating skin wounds. Background technique [0002] Wounds and ulcers that are damage to skin tissue or the like are generally called "wounds", and specific examples thereof include erosions, cuts, abrasions, burns, skin ulcers, bedsores, and the like. [0003] In particular, skin ulcers and decubitus ulcers are often caused by long-term bed rest, diabetes, arteriosclerosis obliterans, and vasculitis, and most of them will last for a long time. Therefore, with the advent of a super-aging society, the number of patients will increase. big social problem. [0004] However, skin ulcers and bedsores are still refractory diseases. [0005] For refractory skin ulcers and decubitus ulcers, the current situation is that conservative treatments using external preparations for wound therapy (patent document 1) such as white sugar / povidone-iodine complexes cannot expect sufficient ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/00A61K47/14A61K47/32A61K47/38A61P17/02
CPCA61P17/02A61K47/32A61K47/14A61K33/00A61K47/38A61K9/0014A61K9/08
Inventor 高木智久浅井纯冈山哲也三浦桂坂上茂树
Owner SUMITOMO SEIKA CHEM CO LTD