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A kind of traditional Chinese medicine composition for treating nephropathy and its preparation method and application
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A technology of composition and traditional Chinese medicine, which is applied in the field of Chinese medicine composition and its preparation for the treatment of kidney disease, and can solve problems such as the advent of Chinese patent medicines
Active Publication Date: 2022-08-09
BEIJING CHINESE MEDICINE HOSPITAL AFFILIATED CAPITAL MEDICAL UNIV
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Embodiment 1
[0036] A traditional Chinese medicine composition for treating nephropathy, comprising the following raw materials: Heishun Tablets (Pao Fuzi) 30g, Astragalus 50g, Ephedra 30g, Guizhi 30g, Ginger 15g, Fangji 30g, Poria 30g, Alisma 15g, and Zhigancao 10g;
[0037] Add water to decoct for 2-4 hours, 2 times in total, concentrate the water decoction, obtain powder after drying, and add pharmaceutically acceptable carriers and / or excipients.
Embodiment 2
[0039] A traditional Chinese medicine composition for treating nephropathy, comprising the following raw materials: Heishun Tablets (Pao Fuzi) 30g, Astragalus 50g, Ephedra 30g, Guizhi 30g, Ginger 15g, Fangji 30g, Poria 30g, Alisma 15g, and Zhigancao 10g; The raw materials are dried, pulverized into fine powder, sieved, and made into granules.
Embodiment 3
[0041] A traditional Chinese medicine composition for treating nephropathy, comprising the following raw materials: Heishun Tablets (Pao Fuzi) 30g, Astragalus 50g, Ephedra 30g, Guizhi 30g, Ginger 15g, Fangji 30g, Poria 30g, Alisma 15g, and Zhigancao 10g;
[0042] Take Heishun tablets, add 2 times of water to soak for 4 hours, adjust the pH to 4, decoct and extract for 2 to 4 hours; Ephedra, Fangji, soak in water to maintain the corresponding pH value during the extraction process, use 1% hydrochloric acid solution and 5% hydrogenSodiumoxide is used to adjust pH value, and ultrafiltration membrane with molecular weight cut-off of 5KD to 10KD is used to remove impurities to obtain an extract, which is spray-dried to obtain powder A; decoction for 2 to 4 hours can effectively remove the toxicity of Heishun tablets, and acid water extraction can The alkaloids are efficiently extracted, and the ultrafiltration membrane can be used to remove impurities and toxic substances.
[004...
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Abstract
The invention discloses a traditional Chinese medicine composition for treating nephropathy, a preparation method and application thereof. 15-30 parts by weight of cinnamon sticks, 5-30 parts by weight of ginger, 5-45 parts by weight of Fangji, 10-60 parts by weight of Poria, 10-30 parts by weight of Alisma, and 5-20 parts by weight of licorice. The invention also discloses a preparation method. The pharmaceutical composition of the invention is a pure traditional Chinese medicine preparation, which achieves the effect of treating membranous nephropathy through the effects of warming yang and replenishing qi, relieving the surface and invigorating water.
Description
technical field [0001] The invention relates to a pharmaceutical composition, in particular to a traditional Chinese medicine composition for treating nephropathy and a preparation method and application thereof. Background technique [0002] Membranous nephropathy (MN) is a common glomerular disease and one of the main causes of nephrotic syndrome in adults. Membranous nephropathy is characterized by diffuse immune deposits under the glomerular epithelium with changes in basement membrane thickening. Clinically, it can be divided into idiopathic membranous nephropathy (IMN) and secondary membranous nephropathy (SMN), of which IMN accounts for about 75%, and the etiology is often unclear; SMN is a common secondary Sexual factors include systemic lupus erythematosus, hepatitis B, malignant tumor and drug poisoning. In my country, the incidence of membranous nephropathy is increasing year by year, from 10.77% in 2009 to 32.98% in 2018, becoming the first primary glomerular d...
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