Phenylethyl resorcinol slow-release oiling agent for whitening skin and fading spots

Abstract

The invention provides a phenylethyl resorcinol slow-release oiling agent for whitening skin and fading spots. The phenylethyl resorcinol slow-release oiling agent for whitening skin and fading spots comprises a caprylic/capric triglyceride matrix, an anti-inflammatory composition and phenethyl resorcinol. The selected anti-inflammatory composition can inhibit and antagonize stimulation of various inflammatory factors and cytokines outside melanocytes to the melanocytes in a multi-target manner, so that the product is higher in whitening and spot-fading efficiency and better in effect. Meanwhile, the anti-inflammatory composition can also improve skin inflammations, such as redness, sensitivity, pruritus, redness and swelling and other symptoms, and gains additional benefits. The oil solution added with the caprylic/capric triglyceride matrix of the phenylethyl resorcinol has strong inhibition on tyrosinase family in melanocytes, so that the whitening and spot fading effects are good, the concentration of the phenylethyl resorcinol smeared on the skin is more stable due to the fact that the pure oil dosage form does not contain water which is easy to evaporate quickly, and the concentration change of the phenylethyl resorcinol inside and outside the skin is small, so that the irritation of the phenylethyl resorcinol to the skin is reduced.

Description

technical field [0001] The invention relates to the technical field of skin care products, in particular to a phenylethyl resorcinol slow-release oil agent for whitening and lightening spots. Background technique [0002] There are two technical defects in the prior art or the skin care products for whitening and lightening spots on the market: [0003] First, in terms of the mechanism of whitening and lightening spots, the existing skin care formulas singlely emphasize the three key tyrosinase families (tyrosinase TYR, DHICA oxidase TRP-1, and polysaccharides) that produce melanin in melanocytes. Bachrome intermutase TRP-2) activity is inhibited to reduce the synthesis of melanin; there is no inhibition or antagonism of various inflammatory factors and cytokines outside the melanocytes, and these factors will stimulate the proliferation and division of melanocytes, tyrosine The concentration of enzymes increases and activates, and the melanin secretion and transport channe...

AI Technical Summary

Problems solved by technology

When the cream is applied to the skin, due to the rapid evaporation of water, the concentration of phenylethyl resorcinol on the skin surface will increase rapidly. The diffusion rate of resorcinol into the inner layer of the skin stimulates the capsaicin receptor TRPV1 in the skin, which will cause discomfort such as skin tingling and redness in the short term, and reduce customer acceptance

At the same time, in the aqueous cream dosage form, because of the presence of moisture and oxygen, phenylethyl resorcinol is easy to hydrolyze, oxidize and photodegrade, making it difficult to store phenylethyl resorcinol stably

According to experience and preliminary data, it will turn yellow and degrade in about half a year, which will affect the actual shelf life and use of the product

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