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Rhubarb-3 granules and preparation process thereof

A preparation process and technology of rhubarb, applied in the field of preparation of Mongolian medicine granules, can solve the problems of difficult extraction by patients, unacceptable taste, easy moldy deterioration, etc., and achieve the effects of improving the utilization rate of medicinal materials, being convenient to take, and keeping the medicinal effect consistent.

Pending Publication Date: 2021-06-04
韩额尔德木图
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It needs to be newly prepared before use, and it is easy to mold and deteriorate after a long time, and it is inconvenient to carry; the volume of consumption is large, and the taste is unacceptable, especially for children; In order to be different, it has become a necessary means to modify the formulation of rhubarb-3 soup to make it more suitable for people's life

Method used

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  • Rhubarb-3 granules and preparation process thereof
  • Rhubarb-3 granules and preparation process thereof
  • Rhubarb-3 granules and preparation process thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Embodiment 1: The preparation process of rhubarb-3 granules, which comprises the following steps: (1) water extraction to prepare rhubarb-3 extract; (2) rhubarb-3 extract concentrated and dried to prepare drug extract powder; (3) drug extract The extraction powder is granulated to obtain rhubarb-3 granules; wherein,

[0026] (1) Water extraction to prepare the rhubarb-3 extract: according to the mass ratio of the rhubarb-3 formula: rhubarb: myrobalan: alkali noodles=1:1:1, take rhubarb, myrobalan and alkali noodles respectively, and weigh the The rhubarb and myrobalan are crushed and passed through a 10-mesh sieve, and then the sieved rhubarb and myrobalan are mixed and extracted with water for 1-3 times, adding 8-16 times the total weight of rhubarb and myrobalan for each extraction, and heated to boil Reflux extraction for 10-60 minutes, soak for 0.5-1.5 hours before the initial extraction, mix the filtrate obtained by filtering after each extraction, and add the weig...

Embodiment 2

[0031] Embodiment 2: The preparation process of rhubarb-3 granules, which comprises the following steps: (1) water extraction and preparation of rhubarb-3 extract; (2) concentration and drying of rhubarb-3 extract to prepare drug extract powder; (3) drug extraction The extraction powder is granulated to obtain rhubarb-3 granules; wherein,

[0032] (1) Water extraction to prepare the rhubarb-3 extract: according to the mass ratio of the rhubarb-3 formula: rhubarb: myrobalan: alkali noodles=1:1:1, take rhubarb, myrobalan and alkali noodles respectively, and weigh the The rhubarb and myrobalan are crushed and passed through a 10-mesh sieve, and then the rhubarb and myrobalan after sieving are mixed and then extracted twice with water, adding 8 times the total weight of rhubarb and myrobalan for each extraction, and heated and boiled under reflux for 60 minutes. Soak for 1 hour before the initial extraction, mix the filtrate obtained by filtering after each extraction, and add the...

Embodiment 3

[0036] Example 3: rhubarb has many types of medicinal active ingredients, among which anthraquinones, anthrone, tannins, stilbenes and polysaccharides are reported more, wherein anthracene derivatives mainly include emodin, rhein, chrysophanol, Active ingredients such as emodin, aloe-emodin and earth emodin. Among them, anthraquinone compounds have a wide range of pharmacological effects, such as purging, antibacterial, antiviral, anticancer, improving eyesight, promoting intelligence, antiaging, antimutagenic, antiultraviolet, protecting liver and gallbladder, etc. Emodin in these components can promote gastrointestinal motility, and its mechanism may be related to increasing the levels of gastrin and motilin in the blood, the level of gastrointestinal hormones, reducing the content of somatostatin, and inhibiting the small intestinal mucosal Na. + -K + -ATPase activity, increased intestinal fluid, increased expression of aquaporin aqp3 in the colon and many other mechanisms...

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Abstract

The invention discloses rhubarb-3 granules and a preparation process thereof. The preparation process of the rhubarb-3 granules comprises the following steps of: (1) preparing a rhubarb-3 extracting solution by water extraction; (2) concentrating and drying the rhubarb-3 extracting solution to prepare medicine extracting powder; and (3) granulating the medicine extracting powder to obtain the rhubarb-3 granules. The rhubarb-3 granules are prepared according to the preparation process of the rhubarb-3 granules. According to the preparation process, a rhubarb-3 decoction is modified into the granules by adopting and optimizing an extraction process of a traditional decoction, so that on one hand, effective components of medicines in a prescription can be fully extracted, and the utilization rate of the medicines is increased; and on the other hand, the prepared granules overcome the trouble of decoction and are convenient to take. Compared with the traditional decoction, the granules prepared by the preparation process are more stable in property and convenient to take, carry and store; and certain additives can be properly added into the granules, so that the taste is more easily accepted, the advantages of traditional Mongolian medicines can be better exerted, and the defects are effectively avoided.

Description

Technical field: [0001] The invention relates to the technical field of preparation of Mongolian medicine granules, in particular to a rhubarb-3 granule and a preparation process thereof. Background technique: [0002] Rhubarb-3 Soup is composed of rhubarb, myrobalan and alkali noodles (because trona is not available in the modern drug decoction market, most modern pharmaceutical companies or hospitals use alkali noodles instead of trona when preparing the drug), which can treat constipation and dredge Intestine and treatment of amenorrhea and other effects, oral, 1.5g ~ 3g, 1 ~ 3 times a day, decoction, pregnant women with caution. The rhubarb in the prescription is a slow laxative medicinal material. The Mongolian name was first recorded in "The Source of Wisdom", and its medicinal use was first recorded in "Eight Branches of Medical Classics". Rhubarb is bitter and sour in taste, cool in nature, thin, light, and active, and mainly has pharmacological effects such as laxa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/708A61K9/16A61P1/10A61P15/00A61K33/00
CPCA61K36/708A61K36/185A61K33/00A61K9/1652A61P1/10A61P15/00A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 韩额尔德木图都丽娜昂格力玛白龙乌日罕孟永梅
Owner 韩额尔德木图
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