A three-dimensional dose prediction method and system in personalized precise radiotherapy planning

A technology of three-dimensional dose and prediction method, which is applied in the cross field of artificial intelligence and medical image processing, to achieve the effect of reducing intervention and improving accuracy

Active Publication Date: 2022-05-20
UNIV OF JINAN
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Problems solved by technology

At the same time, the Markov discriminator is used against the 3D dose distribution prediction image and the 3D dose distribution real image to improve the prediction quality of the 3D dose distribution image, showing strong performance and theoretical advantages in solving the problem of clinical radiation therapy dose prediction

Method used

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  • A three-dimensional dose prediction method and system in personalized precise radiotherapy planning
  • A three-dimensional dose prediction method and system in personalized precise radiotherapy planning
  • A three-dimensional dose prediction method and system in personalized precise radiotherapy planning

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Embodiment Construction

[0088] The present invention will be further described below in conjunction with the accompanying drawings and embodiments.

[0089] The structures, proportions, sizes, etc. shown in the drawings attached to this specification are only used to match the content disclosed in the specification for the understanding and reading of those who are familiar with this technology, and are not used to limit the conditions for the implementation of the present invention , so it has no technical substantive meaning, and any modification of structure, change of proportional relationship or adjustment of size shall still fall within the scope of the disclosure of the present invention without affecting the functions and objectives of the present invention. within the scope of the technical content covered. At the same time, terms such as "upper", "lower", "left", "right", "middle" and "one" quoted in this specification are only for the convenience of description and are not used to limit th...

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Abstract

The invention discloses a method and system for three-dimensional dose prediction in personalized precise radiotherapy planning. The method includes the following steps: Step 1, obtaining computerized tomography images, mask images of dangerous organ structures, and three-dimensional dose distribution images, etc. Radiotherapy-related information; step 2, perform data preprocessing operations on the image in step 1; step 3, input the acquired image data into a two-stage generator network to generate a three-dimensional dose distribution image and a confidence map; step 4, use Marr Cove discriminator against the 3D dose distribution prediction image and the 3D dose distribution real image; step 5, jointly optimize the prediction model through the reconstruction loss function, the reconstruction loss function with confidence weight and the adversarial loss function; step 6, use the trained prediction The model generates a three-dimensional dose distribution. Through the technical solution of the present invention, manual intervention in radiotherapy planning can be reduced, the accuracy of dose prediction can be improved, and individualized precise radiotherapy can be realized.

Description

technical field [0001] The invention relates to the cross field of artificial intelligence and medical image processing, in particular to a three-dimensional dose prediction method and system in personalized and precise radiotherapy planning. Background technique [0002] The traditional radiation therapy plan is completed through repeated discussions and collaborations between clinicians and physicists with relevant professional knowledge, so as to ensure that patients receive the correct treatment plan and high-quality radiation dose, but this means that the completion of a treatment plan It can take several days to formulate, which reduces tumor control and the patient's chances of survival somewhat. To solve this problem, automated radiotherapy planning methods and systems provide a possibility for computer-assisted personalized and precise radiotherapy, thereby shortening the time for radiotherapy planning. In recent years, the rapid development of artificial intelligen...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G16H20/40G16H50/50G06N3/04G06N3/08
CPCG16H20/40G16H50/50G06N3/08G06N3/045
Inventor 牛四杰李帆韩颖颖高希占侯清涛董吉文
Owner UNIV OF JINAN
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