Brain blood oxygen saturation detection system and method free of scalp blood flow interference

Abstract

The invention discloses a brain blood oxygen saturation detection system and method free of scalp blood flow interference. The detection system comprises a sensor and a host, and the sensor is connected with the host through a cable. The sensor is tightly attached to the forehead skin of the head, a first light source, a first detector, a second light source and a second detector are arranged on the sensor, the light sources and the detectors are sequentially and linearly arranged in the same direction, and the detectors can not only pick up absorption information of chromophore substances in scalp blood flow at the incidence position of the light sources but also pick up absorption information of chromophore substances in scalp blood flow at the emergent position of the light source. A power supply module, a central processing and storage module, a light source driving module, a signal amplification and A/D conversion module, a user information input module and a data display module are arranged in the host. According to the method, scalp blood flow interference can be eliminated, so that the brain blood oxygen saturation is obtained.

Description

technical field [0001] The invention relates to the technical field of biomedical engineering, in particular to a system and method for detecting cerebral blood oxygen saturation that are not disturbed by scalp blood flow. Background technique [0002] The oxygen consumption of the brain accounts for about a quarter of the total oxygen consumption of the human body. The brain is highly sensitive to hypoxia. Short-term hypoxia can cause irreversible nerve damage. The incidence of cerebral hypoxia during surgical anesthesia has always been high. Therefore, it is very important to monitor the oxygen supply and consumption of the patient's brain tissue in time during the operation. [0003] Near Infrared Spectroscopy (Near Infrared Spectroscopy, NIRS) is a non-destructive detection technology for cerebral blood oxygen that has emerged in the past 20 years. It uses a near-infrared light source of a specific wavelength to irradiate the forehead. The difference between hemoglobin ...

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Problems solved by technology

[0004] However, when the near-infrared light irradiates the forehead, the chromophore substances (oxyhemoglobin, reduced hemoglobin and cytochrome oxidase) in the blood of the scalp will inevitably absorb the near-infrared light, so the measured data is the brain Blood oxygen saturation and oxygen saturation in the scalp blood flow, and the hemodynamics in the scalp are easily affected by the external environment (such as temperature, sensor wearing tightness, etc.), which will interfere with the test results

Studies by Steven et al. have shown that there are commercial cerebral blood oxygen detection instruments, such as FORE-SIGHT ELITE, INVOS TM 5100C, etc. When the hemodynamics of the scalp changes, the measured cerebral oxygen saturation changes greatly, which affects the stability and accuracy of the test results

[0005] The publication number is CN110613462A, which discloses a tissue oxygen saturation detection method and device not affected by individual differences. This invention corrects the influence of different outer tissue thicknesses on tissue oxygen saturation measurement, but cannot eliminate scalp blood flow interference

Patent No. CN208435654U discloses an infrared light emitting probe for cerebral blood oxygen detection. The probe can fit the scalp better, but it cannot resist scalp blood flow disturbance

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