Lactein tablet with improved taste

The technology of lactobacillus tablet and lactobacillus, which is applied in the field of biomedicine, can solve the problems of heavy sour taste, refusal to take it, inability to prevent or treat, etc., and achieve the effects of moderate sour and sweet taste, simple process and good taste experience.

Inactive Publication Date: 2021-07-20
亚宝药业太原制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since lactic acid bacteria itself has the characteristics of easy absorption and water viscosity, it is very sensitive to the humidity of the environment, and the taste experience effect of lactic acid bacteria tablets will be greatly reduced after being placed for a long time; moreover, lactic acid bacteria itself has a relatively heavy sour taste, Its taste is very bad. For normal people, especially patients with indigestion, the compliance is poor, and it cannot prevent or treat it.
[0003] When lactobacillus tablets are used in practice, taste is a key factor affecting patient acceptance. Currently, the most common lactobacillus tablets on the market have unsatisfactory taste experiences, especially for children, who are often refused to take them. , it is difficult to exert its due curative effect

Method used

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  • Lactein tablet with improved taste

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Experimental program
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Effect test

Embodiment

[0025] Example: According to the method of this application, lactobacillus tablets with the following components were prepared, see Table 4 for details:

[0026] Table 4

[0027] components Prescription 1 Prescription 2 Prescription 3 Lactobacillus 40.00g 45.00g 45.00g lactose 12.00g 9.00g 26.50g Mannitol 6.00g 4.00g 23.50g Aspartame (plus) 0.33g 0.30g 0.80g Fresh Creamer 0.87g 0.87g 1.87g Aspartan (plus) 0.27g 0.30g 0.90g Magnesium stearate 0.39g 0.40g 0.80g Cornstarch (for making binders) 0.12g 0.13g 0.63g

[0028] Weigh each component according to the above amount, and under the condition of ambient humidity of 53% RH, pulverize and sieve lactobacillus, mix it with lactose, mannitol, and aspartame (internal addition), and use cornstarch to prepare the concentration 5% binder is carried out wet granulation; then boiling drying, granulation, the material after granulation is mixed with aspartam...

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Abstract

The invention relates to a lactein tablet with an improved taste. The lactein tablet is prepared from 45%-75% of lactein, 10%-30% of lactose, 6%-25% of mannitol, 0.5%-2% of fresh milk essence, 0.5%-2% of aspartame, 0.6%-0.83% of magnesium stearate and 0.1%-0.65% of corn starch. Compared with existing lactein tablets, the lactein tablet has very good consumer taste experience, the preparation method and the technological process are simple, energy is saved, consumption is reduced, and the obtained lactein tablet is higher in stability and more controllable in quality.

Description

technical field [0001] The invention belongs to the field of biomedicine and relates to a lactobacillus tablet, in particular to a lactobacillus tablet with improved taste and a preparation method thereof. Background technique [0002] Lactobacillus is a digestive over-the-counter drug developed in recent years. It is often used in the treatment of abnormal intestinal fermentation, indigestion, enteritis, and infantile diarrhea. Currently, the preparation types of Lactobacillus on the market include ordinary tablets, chewable tablets, and granules. . Since lactic acid bacteria itself has the characteristics of easy absorption and water viscosity, it is very sensitive to the humidity of the environment, and the taste experience effect of lactic acid bacteria tablets will be greatly reduced after being placed for a long time; moreover, lactic acid bacteria itself has a relatively heavy sour taste, Its mouthfeel is very poor, and for normal people, especially patients with ind...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K47/26A61K47/36A61K35/747A61P1/14A61P1/12
CPCA61K9/2059A61K9/2018A61K35/747A61P1/14A61P1/12
Inventor 李杰张洁石守鹏刘军
Owner 亚宝药业太原制药有限公司
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