Traditional Chinese medicine composition for treating nephrotic syndrome and application thereof

A technology of composition and traditional Chinese medicine, which is applied in the direction of drug combination, medical raw materials derived from leeches/worms, and pharmaceutical formulas, which can solve the problems of easy recurrence, many side effects, and decreased quality of life of patients

Inactive Publication Date: 2021-07-30
浙江省中医院、浙江中医药大学附属第一医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, hormones and immunosuppressant drugs have their own unique effects and usage methods, and they have many side effects, such as physical changes such as full moon face and buffalo back, and changes in mental symptoms, which lead to increased economic, physical, and psychological pressure on patients, and society. Decreased adaptability, increased negative emotions such as anxiety and depression, and reduced quality of life for patients
[0005] The immune function of patients with nephrotic syndrome is generally low, which leads to easy recurrence after remission. Multiple recurrences not only increase the burden on the kidneys, but also damage the kidney function. In severe cases, they can also induce acute renal failure, heart failure, severe infection, thromboembolic syndrome, etc. Fatal complications, must rely on dialysis for maintenance in the later stage, critically ill and even life-threatening at any time

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Embodiment 1, Chinese medicine composition and using method

[0041] 1. Item preparation: traditional Chinese medicine group, treatment bowl, applicator, rice vinegar, honey

[0042] Chinese medicine composition mass parts formula: 15 parts of rehmannia root, 15 parts of yam, 10 parts of dogwood, 10 parts of cinnamon, 10 parts of aconite, 10 parts of Achyranthes bidentata, 10 parts of earthworm, 10 parts of Morinda officinalis, 5 parts of paojiang .

[0043] 2. Chinese medicine production:

[0044] According to the formula, weigh 15g of rehmannia glutinosa, 15g of yam, 10g of dogwood, 10g of cinnamon, 10g of aconite, 10g of Achyranthes bidentata, 10g of earthworm, 10g of Morinda officinalis, and 5g of Paojiang, and grind them into powders (diameter 0.5mm- 1.5mm), mix, add 30g of rice vinegar and honey mixture (mass ratio of rice vinegar: honey 1.5:1), and make a paste. When making the paste, use force evenly to fully mix the powdered medicine with honey and rice vineg...

Embodiment 2

[0056] The traditional Chinese medicine formula of Example 1 was changed to: Rehmannia glutinosa 20g, yam 15g, dogwood 12g, cinnamon 12g, aconite 15g, Achyranthes bidentata 15g, earthworm 12g, Morinda officinalis 12g, Paojiang 9g.

[0057] Adopt the acupoint sticking and using method of embodiment 1.

[0058] Case 2, Yao XX, female, 57 years old, "repeated edema of both lower limbs for 17 years", the patient developed edema of both lower limbs after exertion 17 years ago, and was hospitalized in a tertiary hospital in Hangzhou. Renal biopsy puncture showed: minor glomerular lesions. The edema was relieved by glucocorticoid therapy, diuretic for reducing swelling, ARB to control proteinuria, Bailing Capsules, Nephritis Shu Hushen, etc. After discharge, the patient's urine protein fluctuated from ++ to +++, and he was treated with prednisone combined with cyclosporine, but the urine protein did not decrease, and the lower extremity edema recurred. So I came to our hospital for...

Embodiment 3

[0061] The traditional Chinese medicine formula in Example 1 was changed to: Rehmannia glutinosa 12g, yam 12g, dogwood 9g, cinnamon 6g, aconite 5g, Achyranthes bidentata 9g, earthworm 9g, Morinda officinalis 9g, Paojiang 3g.

[0062] Adopt the acupoint sticking and using method of embodiment 1.

[0063] Case 3, Zhai Moumou, male, 32 years old, "both lower extremities were swollen for more than half a year, and aggravated for one week". The patient developed edema of both lower limbs after exertion more than half a year ago, accompanied by backache and fatigue, and was afraid of cold, which was slightly relieved after rest, but was not taken seriously at that time. One week ago, the patient's edema worsened after staying up late, and the pressure depression was obvious, which was not easy to recover, accompanied by increased foam in the urine, obvious fatigue, and no dizziness. Local hospital hospitalization examination: urine protein qualitative ++++, plasma albumin 20g / L, re...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating nephrotic syndrome and an application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 12-20 parts of radix rehmanniae recen, 12-15 parts of Chinese yam, 9-12 parts of dogwood, 6-12 parts of cinnamon, 5-15 parts of radix aconiti lateralis preparata, 9-15 parts of radix cyathulae, 9-12 parts of earthworm, 9-12 parts of morinda officinalis and 3-9 parts of baked ginger. The traditional Chinese medicine composition provided by the invention adopts an external acupoint application form, transdermal administration and an application promote medicine absorption, and acupoint stimulation is realized, so that the effects of warming kidney and tonifying spleen, promoting blood circulation and dredging collaterals and inducing diuresis to alleviate edema are achieved, proteinuria is reduced, hypoproteinemia is improved, edema is relieved, the immune function of a patient is improved, and the treatment effect is achieved. The composition is safe, free of toxic and side effects, simple and convenient to operate, direct in curative effect, low in price and good in patient compliance.

Description

[0001] (1) Technical field [0002] The invention relates to a traditional Chinese medicine composition and application method for treating nephrotic syndrome. [0003] (2) Background technology [0004] Nephrotic syndrome (Nephrotic Syndrome, NS) is a common clinical symptom caused by a variety of reasons that lead to increased permeability of the glomerular basement membrane. Syndrome and hypoalbuminemia (ie "three highs and one low"). A large amount of urinary protein, that is, the 24-hour urinary protein quantity> 3.5g. Hypoalbuminemia, that is, plasma albumin below 30g / L. NS can be divided into attack period and remission period. In terms of treatment, modern medicine usually controls the development of the disease by helping patients improve their diet, diuretic swelling, reducing urinary protein, hormones, and immunosuppressants. However, hormones and immunosuppressant drugs have their own unique effects and usage methods, and they have many side effects, such as ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/70A61P13/12A61K35/62A61K35/644A61K31/19
CPCA61K9/7023A61K31/19A61K35/62A61K35/644A61K36/21A61K36/40A61K36/54A61K36/714A61K36/746A61K36/804A61K36/8945A61K36/9068A61P13/12A61K2300/00
Inventor 何灵芝吴满满甘安平朱秀芳张缘
Owner 浙江省中医院、浙江中医药大学附属第一医院
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