Preparation method of stem cell apoptotic body for repairing endometrium and improving fertility
An apoptotic body, endometrium technology, applied in the field of stem cell regenerative medicine, can solve the problems of difficult standardization of stem cell treatment, stem cell stemness loss, stem cell tumorigenicity, etc., to promote endometrial repair and reproductive function recovery, The effect of promoting cell proliferation and promoting sustainable release
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[0066] Further description will be given below in conjunction with the embodiments shown in the accompanying drawings.
[0067] The inventors found that the apoptotic body after apoptosis of mesenchymal stem cells can further regulate the immune response of related cells, cell proliferation, cell energy metabolism and angiogenesis, and the apoptotic body and hyaluronic acid hydrogel were combined to construct The hydrogel composite transplantation ultimately promotes tissue regeneration and repair. Therefore, for the first time, the present invention uses active bodies produced by inducing apoptosis of stem cells. The preparation process is simple and the yield is high, which can improve the wound microenvironment of damaged endometrium, thereby promoting endometrial repair and significantly improving fertility.
[0068] The technical solution thus provided by the present invention is: a method for preparing stem cell apoptotic bodies for repairing endometrium and improving fe...
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