Patch type mask containing astaxanthin inclusion compound and preparation method of patch type mask

A technology of astaxanthin and clathrates, which is applied in the field of patch masks containing astaxanthin clathrates and its preparation, can solve the problem that the essence of the mask cannot be fully absorbed by the skin, poor water solubility of astaxanthin, and bioavailability The problem of low efficiency and other problems, to achieve the effect of increasing skin penetration rate, improving bioavailability, scientific and reasonable formula

Pending Publication Date: 2021-10-01
南京中源盛生物科技研究院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0007] Aiming at the deficiencies in the prior art, the present invention provides a patch-type facial mask containing astaxanthin inclusion compound and a preparation method thereof to solve the problem of poor water solubility of astaxanthin, sensitivity to external factors such as light, oxygen, strong acid, etc., biological The utilization rate is low, and the prepared mask essence cannot be fully absorbed by the skin

Method used

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  • Patch type mask containing astaxanthin inclusion compound and preparation method of patch type mask
  • Patch type mask containing astaxanthin inclusion compound and preparation method of patch type mask
  • Patch type mask containing astaxanthin inclusion compound and preparation method of patch type mask

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preparation example Construction

[0036] The preparation method of astaxanthin clathrate comprises the following steps:

[0037] S1. Weigh astaxanthin and hydroxypropyl-β-cyclodextrin according to the mass ratio of 1:5-20, dissolve them in ethanol and ethanol with a concentration of 95% respectively, fill with nitrogen protection, keep warm and magnetically stir, and the embedding reaction reaches Obtain clathrate solution after equilibrium;

[0038] S2. The clathrate solution is placed in a round-bottomed flask, and the ethanol is removed by rotary evaporation under reduced pressure under water bath conditions, and the concentrate is dried at room temperature; wherein, the temperature of the water bath is 37-40°C;

[0039] S3, adding deionized water to the dried concentrate to fully dissolve the clathrate to obtain a clathrate solution;

[0040] S4, suction filtration of the clathrate solution to remove insoluble matter to obtain an orange transparent solution;

[0041] S5. Freeze-dry the orange transparent s...

Embodiment 1

[0048] The sheet mask containing astaxanthin inclusion compound in this embodiment is prepared from mask essence containing astaxanthin inclusion compound and mask cloth. Among them, the mask cloth is selected from 384 silk film cloth.

[0049] Specifically, the facial mask essence is composed of the following components by weight percentage: 2% astaxanthin / hydroxypropyl-β-cyclodextrin inclusion complex, 0.02% tea polyphenols, 0.2% bisabolol, 0.5% tranexamic acid %, Damask rose hydrosol 1%, 1,2-pentanediol 1%, glycerin 2%, 1,3-butanediol 4%, sodium hyaluronate 0.02%, EDTA-2Na 0.02%, xanthan gum 0.05 %, sodium alginate 0.2%, jojoba wax PEG-1200 0.05%, PEG-40 hydrogenated castor oil 0.3%, preservative 0.1%, and the balance is deionized water. Wherein, preservative is selected from phenoxyethanol.

[0050] Among them, astaxanthin is derived from Haematococcus pluvialis, and the astaxanthin inclusion compound is prepared from astaxanthin and hydroxypropyl-β-cyclodextrin at a mas...

Embodiment 2

[0062] The sheet mask containing astaxanthin inclusion compound in this embodiment is prepared from mask essence containing astaxanthin inclusion compound and mask cloth. Among them, the mask cloth is selected from 384 silk film cloth.

[0063] Specifically, the mask essence is composed of the following components by weight percentage: 3% astaxanthin / hydroxypropyl-β-cyclodextrin inclusion complex, 0.05% tea polyphenols, 0.5% bisabolol, 1 tranexamic acid %, Damask Rose Hydrosol 2%, 1,2-Pentanediol 1.5%, Glycerin 2.5%, 1,3-Butanediol 4.5%, Sodium Hyaluronate 0.05%, EDTA-2Na 0.05%, Xanthan Gum 0.1 %, sodium alginate 0.25%, jojoba wax PEG-1200.1%, PEG-40 hydrogenated castor oil 0.4%, preservative 0.2%, and the balance is deionized water. Wherein, preservative is selected from phenoxyethanol.

[0064] Among them, astaxanthin is derived from Haematococcus pluvialis, and the astaxanthin inclusion complex is prepared from astaxanthin and hydroxypropyl-β-cyclodextrin at a mass ratio ...

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Abstract

The invention provides a patch type facial mask containing an astaxanthin inclusion compound and a preparation method of the patch type facial mask, and relates to the technical field of facial masks. The patch type facial mask is prepared from the essence containing the astaxanthin inclusion compound and the facial mask cloth, the formula of the essence of the facial mask is scientific and reasonable, various effective components are compounded, the astaxanthin is included by adopting cyclic oligosaccharide hydroxypropyl-beta-cyclodextrin with the outer part being hydrophilic and the inner part being a lipophilic inner cavity, and the astaxanthin forms a water-soluble inclusion compound, so that the astaxanthin is promoted to effectively penetrate through the skin without changing the skin structure, the skin permeability is increased, the bioavailability of the astaxanthin is improved, and a good anti-aging effect is achieved; the astaxanthin inclusion compound is compounded with a plurality of effective components through the hydroxypropyl-beta-cyclodextrin, so that a good whitening effect is achieved while multiple-effect anti-aging is achieved; and the facial mask cloth improves the fitness, air permeability and moisture permeability of the facial mask, so that the essence of the facial mask is fully absorbed by the skin, deep moisturizing is realized, and multi-effect skin renewing is realized.

Description

technical field [0001] The invention relates to the technical field of facial masks, in particular to a patch-type facial mask containing astaxanthin inclusion compound and a preparation method thereof. Background technique [0002] With the rapid increase of the global aging population and the increasing pressure of people in modern society, people's awareness of skin damage caused by the surge in oxidative stress caused by the increasingly harsh environment continues to deepen, as well as the pursuit of skin health and beauty, and anti-aging problems discussions and the growing demand for anti-aging products. The mask helps the skin to eliminate the products of epidermal cell metabolism and accumulated oily substances, so that the water and other active ingredients in the mask can penetrate into the stratum corneum of the epidermis, making the skin soft and naturally bright and elastic. [0003] Astaxanthin, as a fat-soluble ketone carotenoid, also known as astaxanthin or...

Claims

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Application Information

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IPC IPC(8): A61K8/35A61K8/73A61K8/9789A61K8/34A61K8/44A61K8/02A61Q19/08A61Q19/02A61Q19/00
CPCA61K8/35A61K8/738A61K8/9789A61K8/342A61K8/44A61K8/0212A61Q19/08A61Q19/02A61Q19/00
Inventor 王伟闫紫薇唐璐
Owner 南京中源盛生物科技研究院有限公司
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