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Systems and method of characterizing high risk plaques

A plaque and characterization technology, applied in the generation of 2D images, equipment for radiological diagnosis, image enhancement, etc., can solve the problems of increasing time and resources, time-consuming, and adversely affecting medical expenses

Pending Publication Date: 2021-10-15
클리어리인크
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This process is time consuming and depends on the individual cardiologist's subjective characterization of the coronary angiogram
Due to this limitation, SYNAX scoring is sometimes performed by multiple cardiologists to obtain an average score, which increases the time and resources required to perform the assessment
Furthermore, as with any invasive medical procedure, FFR and SYNTAX scores carry the risk of adverse effects and unnecessary medical costs

Method used

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  • Systems and method of characterizing high risk plaques
  • Systems and method of characterizing high risk plaques
  • Systems and method of characterizing high risk plaques

Examples

Experimental program
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Effect test

Embodiment 1

[0169] Example 1: A method of characterizing coronary artery plaque tissue data and perivascular tissue data using image data collected from computed tomography (CT) scans along blood vessels, the image information including radiodensity values ​​for coronary artery plaques and radiodensity values ​​of perivascular tissue adjacent to coronary artery plaques, the method comprising: quantifying the radiodensity in the region of coronary artery plaques in the image data; quantifying the radiodensity adjacent to coronary artery plaques in the image data The radiodensity in at least one region of the corresponding perivascular tissue; determine the quantified radiodensity value in the coronary artery plaque and the gradient of the quantified radiodensity value in the corresponding perivascular tissue; determine the coronary artery plaque and the corresponding perivascular ratio of quantified radiodensity values ​​within tissue; and characterizing coronary artery plaque by analyzing ...

Embodiment 2

[0170] Embodiment 2: the method of embodiment 1, wherein the perivascular tissue comprises at least one of coronary artery lumen, fat, coronary artery plaque or myocardium.

Embodiment 3

[0171] Embodiment 3: The method of any one of Embodiments 1 and 2, further comprising receiving the image data at the data storage component via a network.

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PUM

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Abstract

A method for characterization of coronary plaque tissue data and perivascular tissue data using image data gathered from a computed tomography (CT) scan along a blood vessel, the image information including radiodensity values of coronary plaque and perivascular tissue located adjacent to the coronary plaque, the method comprising quantifying radiodensity in regions of coronary plaque, quantifying, radiodensity in at least one region of corresponding perivascular tissue adjacent to the coronary plaque, determining gradients of the quantified radiodensity values within the coronary plaque and the quantified radiodensity values within the corresponding perivascular tissue, and determining a ratio of the quantified radiodensity values within the coronary plaque and the corresponding perivascular tissue; and characterizing the coronary plaque by analyzing a gradient of the quantified radiodensity values in the coronary plaque and the corresponding perivascular, and / or the ratio of the coronary plaque radiodensity values and the radiodensity values of the corresponding perivascular tissue.

Description

[0001] Cross References to Related Applications [0002] This application claims U.S. Provisional Application No. 62 / 979,024, filed January 25, 2019, entitled "SYSTEMS AND METHODS FOR CHARACTERIZING HIGH RISK PLAQUES," and RISK PLAQUES" U.S. Nonprovisional Application No. 16 / 750,278. Each of the foregoing applications is incorporated herein by reference in its entirety. technical field [0003] The systems and methods disclosed herein relate to identifying high-risk plaques in coronary arteries, and more particularly to calculating the density of coronary plaque and surrounding tissue by using three-dimensional (3D) models of coronary artery medical images ratio (ratio) to characterize coronary plaque. Background technique [0004] The heart is a muscle that receives blood from several arteries, including the left circumflex artery (LCX) and the left anterior descending artery (LAD), both of which branch off from the left aorta and right coronary artery. Coronary artery ...

Claims

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Application Information

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IPC IPC(8): A61B6/02A61B6/03G06T11/00
CPCG06T7/0012G06T2207/10081G06T2207/30048G06T2207/30101A61B6/504A61B6/481A61B6/032A61B6/5217A61B6/5223G06T7/97G06T2207/10072G06T2207/10028
Inventor J·K·敏
Owner 클리어리인크