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Application of molybdenum and/or tungsten-containing compound in resisting human papilloma virus (HPV) or herpes virus (HSV) and pharmaceutical composition of molybdenum and/or tungsten-containing compound

An anti-human papilloma and herpes virus technology, applied in the field of biomedicine, can solve the problems of long treatment period, wide patient population, high recurrence rate, etc., and achieve the effects of toxic and side effects, strong anti-toxin activity, and quick effect

Pending Publication Date: 2021-11-02
三河市安霸生物技术有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This kind of disease has a large number of patients, a large number of people, a long duration, a high recurrence rate, and it is difficult to cure it. There is no specific medicine, which brings serious harm to people's health and life.
At present, the main way to treat fungal infection is to apply hormone drugs (such as ketoconazole, etc.) to the patient. , take effect slowly
Long-term use of the antiviral drug aciclovir may cause damage to liver or kidney function

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] Prepare a molybdenum oxide aqueous solution with a mass concentration of 0.45%, take 0.5g of tungstomolybdate and add it to 95.5ml of molybdenum oxide aqueous solution to disperse evenly, then add 3.0g of carbomer 940 and 1.0g of glycerin as a gel matrix to mix, and stir evenly. An antiviral gel was obtained after standing for 2 hours. Wherein, the particle size of tungstomolybdate in the gel is 2 μm, and the pH value of the antiviral gel is 4.5.

[0050] According to the national health industry standard WS / T 650-2019 "Evaluation Method for Antibacterial and Antibacterial Effects", the prepared antiviral gel was entrusted to Guangzhou Institute of Microbiology Co., Ltd. to conduct antibacterial performance experiments. The antibacterial rate against Escherichia coli and Staphylococcus aureus is greater than 99.9%, and the antibacterial rate against Candida albicans is 99.1%. Has a strong antibacterial effect.

[0051] According to the test method specified in Appendi...

Embodiment 2

[0054] Take 0.5g of tungsten molybdate and add 1.0g of Carbomer 940 to the gel matrix, stir well, add 97.3ml of purified water, add 0.2g of neutralizing agent triethanolamine, stir evenly, add 1.0g of glycerin, stir well, let stand An antiviral gel was obtained after 2 hours. Among them, the particle size of tungstomolybdoxic acid in the gel is 2 μm, and the pH value of the antiviral gel is 5.5.

[0055] The prepared antiviral gel was subjected to an antibacterial performance experiment according to the national health industry standard WS / T 650-2019 "Evaluation Method for Antibacterial and Antibacterial Effects". The results showed that the antibacterial effect of the antiviral gel on E. coli and Staphylococcus aureus Rates are greater than 99.20%, the antibacterial rate of Candida albicans greater than 95.5%.

[0056] According to the test method specified in Appendix C of the national standard GB15979-1995 "Hygienic Standards for Disposable Hygienic Products" or the test m...

Embodiment 3

[0059] Take 0.8g of tungstomolybdate and add 4.0g of guar gum to the gel base, stir evenly, add 94.2ml of purified water and 1.0g of glycerin, stir evenly to form an antiviral gel. Wherein, the particle size of the tungstomolybdic acid in the gel is 2 μm, and the pH value of the antiviral gel is 6.0.

[0060] The prepared antiviral gel was subjected to an antibacterial performance experiment according to the national health industry standard WS / T 650-2019 "Evaluation Method for Antibacterial and Antibacterial Effects". The results showed that the antibacterial effect of the antiviral gel on E. coli and Staphylococcus aureus Rates are greater than 99.50%, antibacterial rate of Candida albicans greater than 95.85%.

[0061] According to the test method specified in Appendix C of the national standard GB15979-1995 "Hygienic Standards for Disposable Hygienic Products" or the test method specified in other equivalent international standards, national standards or industry standards...

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Abstract

The present invention provides the use of a molybdenum and / or tungsten-containing compound in resisting human papilloma virus (HPV) or herpes virus (HSV). As an antiviral substance, the compound containing molybdenum and / or tungsten can quickly kill and permanently inhibit pathogenic microorganisms (bacteria, viruses and molds) and multi-drug-resistant bacteria; the traditional Chinese medicine composition can be used for treating and relieving various symptoms caused by human papilloma virus HPV and herpes virus HSV, and has the advantages of quick effect and strong disinfection activity, and the antiviral substances are not absorbed by the human body and do not generate toxic and side effects; the compound can be used for reducing the load of local human papilloma virus (HPV) and herpes virus (HSV) of a human body, and can also be used for preparing medicines, medical instruments, disinfectants and other auxiliary nursing products for treating various human skin or skin mucosa diseases caused by pathogenic microorganisms.

Description

technical field [0001] The invention belongs to the field of biomedicine, and specifically relates to the use of compounds containing molybdenum and / or tungsten in resisting human papillomavirus HPV or herpes virus HSV, and a pharmaceutical composition thereof. Background technique [0002] Scientific research has found that skin diseases caused by microorganisms, such as skin ringworm, human papillomavirus HPV, and herpes virus HSV, are caused by the reproduction and growth of pathogenic microorganisms (bacteria, fungi and viruses) on the skin. Such diseases have a large number of patients, a large number of people, a long duration, a high recurrence rate, difficulty in radical cure, and no specific medicine, which brings serious harm to people's health and life. At present, the main way to treat fungal infections is to apply hormone drugs (such as ketoconazole, etc.) , take effect slowly. [0003] For low-risk HPV infection, there are still some drugs that are effective....

Claims

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Application Information

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IPC IPC(8): A61K33/24A61K9/06A61K47/36A61P31/22A61P31/20
CPCA61K33/24A61K9/06A61K47/36A61P31/22A61P31/20A61K2300/00
Inventor 林玉平孙卓然林春平林雪
Owner 三河市安霸生物技术有限公司
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