A fluorescent reagent for detecting organic phosphate and its preparation method

Abstract

The invention belongs to the field of chemical analysis and testing, and in particular relates to a fluorescent reagent for detecting organic phosphate and a preparation method thereof. The reagent is a symmetrical squaraine compound based on an 8-aminoquinoline skeleton. Using 4-hydrazinobenzoic acid as a raw material, forming a ring with 3-methyl-2-butanone, and then connecting ethyl iodide, the product obtained and 3,4-dihydroxy-3-cyclobutene-1,2- Diketones react to give fluorescent dyes. Then 8-aminoquinoline is reacted with chloroacetyl chloride, and the product is reacted with p-phenylenediamine to obtain the recognition part. Finally, the fluorescent dye and the recognition moiety are under N,N-diisopropylethylamine basic conditions, in 2-(7-azabenzotriazole)-N,N,N',N'-tetramethyl The final compound was obtained under the catalysis of urea hexafluorophosphate. The compound of the present invention has excellent optical performance and ion selectivity, and in Zn 2+ With participation, the fluorescence response recognition detection of organophosphates can be performed.

Description

A kind of fluorescent reagent for detecting organophosphate and preparation method thereof technical field The invention belongs to the field of chemical analysis and testing, be specifically related to a kind of fluorescent reagent for detecting organophosphate and its preparation method. Background technique Organophosphate esters (organophosphate esters, OPEs) are a class of important organic compounds, widely It is used in the fields of building materials, flame retardants, pesticides, insecticides and other fields of textiles and electronic equipment. such as soman and tabun OPEs are very toxic and are used as "nerve agents"; similarly, OPEs as flame retardant materials, with the amount of The amount of water discharged into the environment also increases year by year, which brings a series of environmental problems. In some typical Chinese The presence of OPEs has been detected in the monitoring of rivers and lakes such as the Yangtze River, Pearl River, an...

AI Technical Summary

Problems solved by technology

They show good optical properties in the ultraviolet to visible region, but there is no corresponding probe compound in the near-infrared region

Images