Radioactive microshperes for the treatment of CNS tumours
A central nervous system and radionuclide technology, applied in the direction of radioactive physical shape, antineoplastic drugs, preparations for in vivo experiments, etc., can solve problems such as poor results
Pending Publication Date: 2021-12-28
BIOCOMPATIBLES UK LTD +1
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The current standard of care is external beam radiation therapy (EBRT
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[0075] The present disclosure will now be described by reference to the following non-limiting illustrative examples. Based on these embodiments, other embodiments will occur to those skilled in the art.
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Abstract
A method of treating CNS tumors such as gliomas is provided comprising delivering a beta-emitting radionuclide containing composition to the tumor via the cerebral vasculature.
Description
[0001] related application [0002] This application claims the benefit of U.S. Provisional Patent Application Serial No. 62 / 816,833, filed March 11, 2019, and U.S. Provisional Patent Application Serial No. 62 / 823,954, filed March 26, 2019, the entire disclosures of which are incorporated in Incorporated herein by reference. technical field [0003] The present disclosure relates to the treatment of central nervous system cancers using beta-radiation emitting radionuclides (β-emitting radionuclides), especially when delivered via cerebral blood vessels. In particular, the present disclosure relates to the use of injectable compositions comprising substances comprising radionuclides in the treatment of central nervous system cancers, more particularly high grade axial brain tumors, including hypervascularized tumors such as gliomas. Background technique [0004] Central nervous system (CNS) cancers are very difficult to treat, with high-grade gliomas being difficult to remo...
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Login to view more IPC IPC(8): A61K51/12
CPCA61P35/00A61K2121/00A61K51/1251A61K9/0019A61K51/1255
Inventor 亚历山大·帕赛克克利福德·韦斯马修·R·德雷尔
Owner BIOCOMPATIBLES UK LTD
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