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Ganu capsule and preparation method thereof

A technology of Gansu capsule and its production method, which is applied in the field of Gansu capsule and its production, which can solve the problems of complex production process, loss of drug effect, incomplete absorption of drug effect, etc., achieve good effect, prolong action time, reduce enzyme Good effect on liver protection

Active Publication Date: 2022-03-04
ZHEJIANG WECOME MEDICINE IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, in the existing Gansu capsules, the Gansu capsule particles are packed into the capsule shell, and the Gansu capsules are used to treat hepatitis. After the Gansu capsule shell is absorbed and dissolved by the gastric mucosa, the Gansu capsule particles will all dissolve into the gastric juice , is absorbed by the gastric mucosa, and then acts on the human liver, but all Gansu capsule particles are dissolved in the gastric juice at the same time, and the drug effect will not be fully absorbed by the gastric mucosa, which may cause a part of the drug effect to be lost, so that the drug effect cannot be absorbed. It is completely absorbed, and the effective solution of the existing technology is coating technology. The surface of the drug particles is covered with films of different thicknesses to make the drug continuously dissolve, and the drug is administered uniformly so that the drug effect can be fully absorbed by the human body. However, the drug The particles are small, and different drug particles are coated to different degrees, and the production process is more complicated

Method used

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  • Ganu capsule and preparation method thereof
  • Ganu capsule and preparation method thereof
  • Ganu capsule and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0030] The production method of the liver sugar capsule is as follows: Take the roots 5556g, cut, add water to cook three times, 2 hours each time, then combine the decoction, filter the decoction, the filtrate is concentrated to the relative density of about 1.15-1.1860 ° C-65 The cleans of ° C, refrigerated, adding ethanol to 60%, then stirred, stand for 22 hours, filtered, precipitate three times with 60% ethanol, combined with the filtrate, and recover ethanol to an alcohol to an alcohol The flavor is concentrated to a cleaner having a relative density of 1.0880 ° C, spray drying, silica and talc powder, is made of liver granules or powder, dry, loaded into the capsule shell, and is obtained.

[0031] The liver particles made of this method are brown to tan powder or granules, slightly bitter,, mainly used for disaster enzyme, protect liver, retreat, spleen for chronic active hepatitis, hepatitis B, Acute viral hepatitis can also be used.

Embodiment 2

[0033] See Figure 1-5 A liver sugar capsule, including capsule shells and liver particles in the capsule shell inside. Capsules include capsule housing 1, sustained release structure 2, and hepol particles 3, the capsule housing 1 includes an upper casing 11 and a lower case 12, and the inner wall of the upper casing 11 is passed from the outer wall of the lower casing 12.

[0034] The sustained release structure 2 is mounted in the lower shell 12, the lower case 12 is dissolved in the gastric liquid, and the hepatic suede 3 is placed in the sustained release structure 2, and the sustained release structure 2 is used to gradually release the efficacy of the hepatic soda 3, and the sustained release structure 2 includes The structure of the three-packing skeleton 21, the three-fitting skeleton 21 is the same, and the outer wall of the charge skeleton 16 is in contact with the inner wall of the lower case 12, so that the capsule is compact, the air is as small as possible in the cap...

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Abstract

The invention relates to the field of capsules, and discloses a Ganu capsule which comprises a capsule shell and Ganu particles contained in the capsule shell. The Gusu granules comprise penthorum chinense pursh clear paste, silicon dioxide and talcum powder, and the penthorum chinense pursh clear paste is prepared by the following steps: chopping penthorum chinense pursh with proper weight, adding water, boiling for N times, combining decoction, filtering, filtering and concentrating into clear paste, adding ethanol to obtain mixed liquor, standing for a period of time, filtering to obtain precipitate, washing the precipitate with ethanol for M times, combining washing liquor and filtrate, and drying to obtain the Gusu granules. Recovering ethanol under reduced pressure until no alcohol smell exists, concentrating to obtain clear paste, and performing spray drying to obtain penthorum chinense pursh clear paste; the capsule shell comprises a capsule shell body and a slow-release structure, the slow-release structure is used for containing Ganu granules and installed in the capsule shell body, a floating piece is arranged on the outer side wall of the upper shell body, and a pendant is arranged on the inner bottom wall of the lower shell body. The traditional Chinese medicine composition is used for chronic active hepatitis and hepatitis B.

Description

Technical field [0001] The present invention relates to the field of capsules, and is specifically a liver sugar capsule and a method of making it. Background technique [0002] With capsule, it is generally a stimulating powder or particle for the esophagus and gastric mucosa, or the mouthfeel is not good, easy to volatilize, is easy to decompose by saliva in the mouth, and the drug that is easily inhaled. These drugs are loaded into the capsules, which protects both drugs that are not destroyed and also protects the digestive organs and respiratory tract. [0003] However, the existing liver supertone is loaded into the capsule housing, and the liver supertone is used to treat hepatitis. After the hepatic supertone enclosure is dissolved, the hepatic supertone particles will be dissolved into the gastric liquid. The gastric mucosa is absorbed, and then all the liver suggestions are simultaneously dissolved in the gastric juice at the same time, and the drug effect will not be a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/52A61K36/185A61K47/04A61K47/02A61P1/16A61J3/07
CPCA61K36/185A61K9/1611A61P1/16A61J3/071A61K2236/331A61K2236/55A61K2236/51Y02A50/30
Inventor 吴建明丁京伟
Owner ZHEJIANG WECOME MEDICINE IND
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