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Mild whitening composition and preparation method thereof

A composition and a whitening technology, applied in the field of whitening compositions, can solve the problems of single action and effect, insufficient whitening mechanism, poor use effect, etc., and achieves increasing skin gloss, inhibiting tyrosinase activity, and mildness. Good results

Active Publication Date: 2022-03-18
ZHEJIANG YIGE ENTERPRISE MANAGEMENT GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Although there are licorice glabra and peony extracts in the current whitening agents, the effect route is single and the whitening mechanism is not comprehensive enough, especially glabridin, which is not stable enough in the formula, and the effect is not good. Irritation, poor experience, there are certain safety hazards, and the application of bird's nest acid is less, there is no whitening composition product that contains glabra, peony and bird's nest acid at the same time

Method used

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  • Mild whitening composition and preparation method thereof
  • Mild whitening composition and preparation method thereof
  • Mild whitening composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A preparation method of a mild whitening composition, comprising the following steps:

[0024] S1. Take the peony callus, dry it under sterile conditions, use filter paper to blot the surface of the medium residue in the ultra-clean bench, quickly freeze it, and freeze it after the freeze-drying treatment, take it out after 40-60 hours, and put it in liquid nitrogen Quick-freezing, then grinding into powder to obtain freeze-dried powder of peony callus;

[0025] Among them, the callus of Paeoniae Alba was in a state of no browning, no vitrification and good growth. The peony callus is obtained by culturing the peony seeds into the peony explants, and after induction and subculture.

[0026] The induction medium is supplemented with 1 / 2MS medium, and the 1 / 2MS medium is supplemented with 6-9mmol / L Ca 2+ , 1-3mg / L 6-BA, 0.2-0.6mg / L NAA, 0.1-0.3mg / L 2,4-D and 0.05-0.2mg / L MT.

[0027] The subculture medium adopts 1 / 2MS medium, and the contents of 0.2-0.8mg / L NAA, 0.2-0....

Embodiment 2

[0032] A preparation method of a mild whitening composition, comprising the following steps:

[0033] S1. Take the peony callus, dry it under aseptic conditions, use filter paper to blot the residual culture medium on the surface in the ultra-clean bench, quickly freeze it, and then freeze it dry, take it out after 48 hours, and freeze it with liquid nitrogen. Then grind into powder to obtain the freeze-dried powder of peony callus;

[0034] Among them, the callus of Paeoniae Alba was in a state of no browning, no vitrification and good growth.

[0035] S2. Adding butanediol as a solvent to the freeze-dried powder of peony callus for extraction, the solid-liquid ratio of the freeze-dried powder of peony callus and glycerin is 1g:20mL, the extraction temperature is 50°C, and the extraction time is 60min, to obtain Peony extract;

[0036] S3. Fully mix the peony extract, the pure powder of bird's nest acid and the pure powder of glabridin, wherein the content of the pure powde...

Embodiment 3

[0039] A preparation method of a mild whitening composition, comprising the following steps:

[0040] S1. Take the peony callus, dry it under aseptic conditions, use filter paper to blot the residual culture medium on the surface in the ultra-clean bench, quickly freeze it, and then freeze it dry, take it out after 48 hours, and freeze it with liquid nitrogen. Then grind into powder to obtain the freeze-dried powder of peony callus;

[0041] Among them, the callus of Paeoniae Alba was in a state of no browning, no vitrification and good growth.

[0042] S2. Add butanediol as a solvent to the freeze-dried powder of peony callus for extraction. The solid-liquid ratio of the freeze-dried powder of peony callus and glycerol is 1g:15mL, the extraction temperature is 50°C, and the extraction time is 60min, to obtain Peony extract;

[0043] S3. Fully mix the peony extract, the pure powder of bird's nest acid and the pure powder of glabridin according to a certain ratio, wherein the...

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Abstract

The invention discloses a preparation method of a mild whitening composition, which comprises the following steps: S1, taking paeonia lactiflora callus, drying and quickly freezing under a sterile condition, sequentially performing freeze-drying treatment and liquid nitrogen quick freezing, and grinding into powder to obtain paeonia lactiflora callus freeze-dried powder; s2, polyhydric alcohol is added into the peony callus freeze-dried powder for extraction, and a peony extract is obtained; s3, the Chinese herbaceous peony extract, sialic acid and glabridin are fully mixed, the content of sialic acid is 0.01-0.22 wt%, the content of glabridin is 0.01-0.2 wt%, the balance is the Chinese herbaceous peony extract, and the whitening composition is obtained. The device has the characteristics of high experience comfort and multi-angle synergistic whitening.

Description

technical field [0001] The invention relates to a whitening composition, in particular to a mild whitening composition and a preparation method thereof. Background technique [0002] With the rapid development of modern society and economy, consumers hope to use more natural, more effective and healthier products in the field of whitening cosmetics. Studies have shown that the main cause of skin darkening is melanin produced by melanocytes in the skin. In current whitening cosmetics, the main products are to achieve whitening and brightening effects by using exfoliating agents (fruit acids) or tyrosinase inhibitors (such as arbutin, Vc, etc.). Although such products can achieve a relatively significant whitening effect in a short period of time, their mode of action is relatively single, and there are certain safety hazards for users. Therefore, it is very valuable to develop whitening products with plant extracts as the main whitening functional ingredients. [0003] Gly...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/49A61K8/60A61K8/34A61Q19/02A61Q19/08
CPCA61K8/9789A61K8/498A61K8/60A61K8/345A61Q19/02A61Q19/08A61K2800/84A61K2800/592A61K2800/782A61K2800/522Y02A50/30
Inventor 张大勇毕永贤孔德承周浩淼李昊朱秀洁
Owner ZHEJIANG YIGE ENTERPRISE MANAGEMENT GRP CO LTD
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