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Composition of prebiotics and probiotics and application thereof

A technology of probiotics and compositions, applied in the field of prebiotics and probiotic compositions, can solve problems such as inability to guarantee product efficacy, and achieve the effects of relieving food allergy, allergic asthma, and specific dermatitis

Pending Publication Date: 2022-04-22
HYPROCA NUTRITION CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the product production process, the efficacy of the product cannot be guaranteed after the composition of different raw and auxiliary materials

Method used

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  • Composition of prebiotics and probiotics and application thereof
  • Composition of prebiotics and probiotics and application thereof
  • Composition of prebiotics and probiotics and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Example 1 Application of prebiotics and probiotic compositions in alleviating bacterial diarrhea

[0019] 1. Detection content

[0020] Taking BALB / c mice as the research object, by intragastric administration of different sample solutions to the mice, the effects of these samples on the fecal water content, serum immune inflammatory factors, and jejunum histopathology of mice with diarrhea were detected, and it was determined that these samples were effective in alleviating bacterial infection. Efficacy and differences in sexual diarrhea.

[0021] 2. Animal experiment protocol

[0022] Male SPF grade BALB / c mice (6 weeks old, body weight 18-20g) after one week of adaptive feeding, the mice were randomly divided into blank control group, model group, composition low-dose group (36.9mg / only / d), In the composition high-dose group (184.5mg / piece / d), the composition samples were all dissolved in 0.2mL sterile physiological saline, and processed by intragastric administrat...

Embodiment 2

[0055] Example 2 Application of Prebiotics and Probiotics Composition in Alleviating Constipation

[0056] 1. Content

[0057] Taking BALB / c mice as the research object, by administering probiotics to the mice, the effects of these samples on the water content of the stool, the propulsion rate of the small intestine, and the time of the first black stool in the mice with constipation were detected, and the effect of the samples on alleviating constipation was determined. effects and differences.

[0058] 2. Program

[0059] 6-week-old SPF grade BALB / c male mice were randomly divided into groups according to 6 mice per group after a week's adaptation period, including blank control group, model group, and composition low-dose group (36.9mg / only / d), In the composition high-dose group (184.5mg / piece / d), the composition samples were all dissolved in 0.2mL sterile physiological saline, and processed by intragastric administration according to the requirements of Table 5, and the ...

Embodiment 3

[0088] Example 3 Application of prebiotics and probiotics composition in aiding digestion

[0089] 1. Content

[0090] Taking BALB / c male mice as the research object, by gavage different samples to the mice, detect the effects of these samples on the mouse body weight growth rate, food utilization rate, and pepsin activity, and determine the efficacy of these samples in aiding digestion and differences.

[0091] 2. Program

[0092] Choose 6-8 weeks of age, 18-22g SPF level BALB / c male mouse, comprise blank control group, composition low-dose group (36.9mg / only / d), composition high-dose group (184.5mg / only / d) d), 6 mice in each group, the composition samples were all dissolved in 0.2mL sterile normal saline, and processed by gavage according to the requirements of Table 8, and the blank control group and the model group were gavaged with 0.2ml sterile normal saline, wherein The weight ratio of each component of the composition is (Lactobacillus rhamnosus MP108:FOS:GOS:resist...

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Abstract

The invention discloses a composition of prebiotics and probiotics and application of the composition. The prebiotics in the composition are fructo-oligosaccharide (FOS), galactooligosaccharide (GOS) and resistant dextrin. The probiotics are lactobacillus rhamnosus MP108, and the probiotics are lactobacillus rhamnosus MP108; the weight ratio of the lactobacillus rhamnosus MP108 to the fructo-oligosaccharide FOS to the galactooligosaccharide GOS to the resistant dextrin is (0.2 to 3): (5 to 8): (5 to 80): (1 to 30). The composition of prebiotics and probiotics can be used for preparing bacterial diarrhea alleviators, constipation alleviators, digestion promoting preparations, food allergy efficacy evaluation preparations, allergic asthma alleviators, dermatitis alleviators, bacterial inhibitors and acid-resistant choline-resistant preparations.

Description

technical field [0001] The invention belongs to the technical field of food nutrition, and in particular relates to a composition of prebiotics and probiotics and an application thereof. Background technique [0002] At present, in the actual production process of the composition, only the probiotic powder is added, which will cause the powder to adhere to the wall of the bar bag and cannot be poured out, resulting in a large loss of probiotics. Lactobacillus rhamnosus MP108 is the first edible strain for infants and young children with China's independent intellectual property rights approved by the Chinese Health Commission. At present, there is no patent application for the combination of Lactobacillus rhamnosus MP108 and prebiotics, or the application of this combination to sample products. [0003] The efficacy of the existing probiotic products is to directly use the functions of the high content of the raw and auxiliary materials themselves, and there is no functiona...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/21A23L33/135
CPCA23L33/21A23L33/135A23V2002/00A23V2400/175A23V2200/3204A23V2200/304A23V2200/318A23V2200/30A23V2250/28A23V2250/5114
Inventor 赵玥明吴桐赵怡晴侯艳梅
Owner HYPROCA NUTRITION CO LTD
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