Hyaluronic acid oral liquid easy to absorb and application

A technology of hyaluronic acid and hyaluronate, which is applied in the fields of application, function of food ingredients, food ingredients containing natural extracts, etc., can solve problems such as slow onset of action, difficulty in absorbing hyaluronic acid, loss of effect, etc., to achieve Quick onset, good moisturizing effect, easy absorption effect

Pending Publication Date: 2022-05-13
浙江瘦金体健康科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to solve the problems in the prior art that hyaluronic acid is difficult to be absorbed, slow to take effect, and quickly loses its effect after discontinuation, the present invention provides an easily absorbable hyaluronic acid oral liquid and its application

Method used

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  • Hyaluronic acid oral liquid easy to absorb and application
  • Hyaluronic acid oral liquid easy to absorb and application
  • Hyaluronic acid oral liquid easy to absorb and application

Examples

Experimental program
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Effect test

preparation example Construction

[0053]The preparation method of the centella asiatica extract comprises the following steps: soaking the centella asiatica in water, heating and refluxing at 80°C for 20 hours, and then filtering successively, concentrating the filtrate, and drying to obtain the centella asiatica extract.

[0054] The preparation method of the aloe extract comprises the following steps: after squeezing the aloe, concentrating the squeezed solution at 70° C. for 15 hours, and drying the concentrated solution in a vacuum to obtain the aloe extract.

[0055] The preparation method of the pomegranate extract comprises the following steps: soaking the pomegranate peel, pomegranate pulp and pomegranate seeds in water, performing ultrasonic extraction at 40° C. for 10 hours, filtering in sequence, concentrating the filtrate, and drying to obtain the pomegranate extract.

Embodiment 1

[0057] The mass percentage of each component of Example 1 in the hyaluronic acid oral solution is shown in Table 1 below. The preparation process of the hyaluronic acid oral liquid of embodiment 1 is as follows:

[0058] (1) Under the condition of maintaining room temperature, slowly add the components shown in Table 1 into 35°C water according to the above proportions, mix and stir evenly until completely dissolved;

[0059] (2) Ultrasonic is carried out to oral liquid, and the temperature of ultrasonic is 50 ℃, and the power of ultrasonic is 300W;

[0060] (3) The oral liquid after ultrasonication is membrane-filtered with a nylon membrane with a pore size of 0.22 μm;

[0061] (4) cooling process is carried out to oral liquid, the temperature of oral liquid is cooled to below room temperature;

[0062] (5) Aseptic filling is adopted;

[0063] Specifically, a high-voltage pulsed electric field (field strength of 50K / cm, pulse number of 350, and pulse frequency of 450Hz) wa...

Embodiment 2～ Embodiment 5

[0066] Embodiment 2~Example 5, Comparative Examples 1~5

[0067] The oral liquid was prepared according to the component formula shown in Table 1, and the operating conditions of the preparation method were all the same as in Example 1.

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Abstract

The invention discloses an easy-to-absorb hyaluronic acid oral liquid and application thereof. The oral liquid comprises hyaluronate, xanthan gum, vitamin B6, a centella asiatica extract, an aloe extract, caffeine, a pomegranate extract, a sweetening agent and water. The molecular weight of the hyaluronate is 10 to 50 kDa, and the pH value of the hyaluronate is 6.5 to 7.0; the molecular weight of the xanthan gum is 300-500 million; the content of the hyaluronate is 1.0 to 1.85 percent; the content of xanthan gum is 1.2 to 2.0 percent; the content of the vitamin B6 is 0.3 to 0.8 percent; the content of the centella asiatica extract is 0.2 to 0.5 percent; the content of the aloe extract is 2 to 2.6 percent; the content of caffeine is 0.05 to 0.2 percent; the content of the pomegranate extract is 6-9.5%; and the content of the sweetening agent is 0.01-0.05%. The effective components of the oral liquid are easily absorbed by human bodies, take effect quickly, and still have long-time moisturizing and skin brightening effects after being stopped.

Description

technical field [0001] The invention relates to an easily absorbed hyaluronic acid oral liquid and its application. Background technique [0002] Hyaluronic acid, also known as hyaluronic acid, is an important part of the cell matrix, widely distributed in the human body, and exerts a variety of physiological functions. Hyaluronic acid has strong biocompatibility, strong water-locking properties and viscoelastic lubricating properties, and has extremely high application value. In addition to being widely used in the medical field and make-up / base makeup, hyaluronic acid has also expanded its application in health food in recent years, and beauty is the most publicized effect of oral hyaluronic acid. [0003] However, hyaluronic acid will be partially destroyed when it passes through the digestive tract during consumption, and then absorbed into the blood through the intestinal tract for transport, and the hyaluronic acid that enters the blood is easily degraded, making it d...

Claims

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Application Information

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IPC IPC(8): A23L33/10A23L33/15A23L33/125A23L33/105
CPCA23L33/10A23L33/15A23L33/125A23L33/105A23V2002/00A23V2200/318A23V2250/21A23V2250/5086A23V2250/7052
Inventor 朱勇姚抗邓道明孙艺军
Owner 浙江瘦金体健康科技有限公司
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