Novel pediatric composition
A composition, a technology of an aqueous composition, applied in the field of aqueous compositions for the treatment or prevention of pain in children, emergency vehicles, pre-filled and ready-to-use nasal spray devices, kits, and intranasal spray applications, capable of solving problems not close to medical facilities (Issues such as hospitals, or doctors with access to pain relief medications, etc.
Pending Publication Date: 2022-06-03
CESSATECH AS
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- Abstract
- Description
- Claims
- Application Information
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Problems solved by technology
The problem of pain relief in children, especially in situations where pain treatment is urgently needed but not in close proximity to medical facilities (such as hospitals, or doctors with access to pain relief medications), has been identified and addressed
Method used
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[0020] In a broad aspect, the present invention relates to an aqueous composition for intranasal spray administration comprising (a) sufentanil, its salts and / or its analogues and (b) ketamine, its salts and / or its analogues mixed solution of substances.
[0021] As used herein, the term "aqueous composition" refers to a liquid composition wherein the carrier is water, eg, sterile water. Depending on the drug to be dissolved therein, other additives may be necessary, such as solubilizers, preservatives, etc., may be added.
[0022] As used herein, the term "intranasal spray administration" refers to the application of an aqueous composition to the nostrils of a human subject by means of a spray (eg, a nozzle or gun nozzle capable of blowing the composition into the nostrils as small droplets), which The aqueous composition is, for example, a mixed solution of the above-mentioned (a) and (b), or the (a) solution and (b) solution from separate containers.
[0023] As used here...
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Abstract
The present invention relates to an aqueous composition for intranasal spray application comprising a mixed solution of (a) sufentanil, salts and / or analogs thereof, and (b) ketamine, salts and analogs thereof. The invention also relates to an aqueous composition for intranasal spray application comprising (a) a solution of sufentanil, a salt thereof and / or an analog thereof, and an aqueous composition for intranasal spray application comprising (b) a solution of ketamine, a salt thereof and / or an analog thereof, for use in a method of treating or preventing pain in children. The composition can be used for treating or preventing pain in children aged 17 or below. The composition is delivered from a nasal spray device to treat or prevent pain in a child, such as operative pain.
Description
technical field [0001] The present invention relates to an aqueous composition for intranasal spray administration comprising (a) a solution of sufentanil, its salts and / or its analogues, and a solution comprising (b) a solution of ketamine, its salts and / or its analogues Aqueous compositions for intranasal spray administration. Combinations of these compositions are useful in methods of treating or preventing pain in children. Specifically, the aqueous compositions are used in methods of treating or preventing pain in children and administered by a nasal spray device. The present invention also relates to pre-filled and ready-to-use nasal spray devices, kits, and emergency vehicles including the nasal spray devices or kits. The present invention also relates to methods of treating or preventing pain in children. Background technique [0002] Hospitalized children experience painful medical procedures that can leave lasting negative effects. Medical procedures range from...
Claims
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IPC IPC(8): A61K31/4535A61K9/08A61P29/00A61P29/02A61K31/135
CPCA61K31/135A61K31/4535A61K9/0073A61K9/0043A61K9/08A61P29/02A61P29/00A61K2300/00A61K31/4468
Inventor S·亨内贝里B·N·尼尔森
Owner CESSATECH AS