Preparation method and application of supramolecular ginger oil nanoemulsion for promoting microcirculation

A technology of molecular ginger oil and nano-emulsion, which can be applied in cosmetic preparations, skin care preparations, medical preparations containing active ingredients, etc., and can solve problems such as poor blood circulation, low immunity, and poor gastrointestinal function. Problems, to achieve the effect of antibacterial blood circulation, promote blood circulation, good bactericidal effect

Pending Publication Date: 2022-07-12
SHENZHEN SHINESKY BIOLOGICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, due to lack of exercise and physical health care, many people are in a sub-health state and have symptoms of sub-health, such as poor blood circulation, low immunity, poor gastrointestinal function, dizziness, vomiting, poor cardiovascular function, intestinal poor peristalsis, digestive disorders, constipation, dysentery, dizziness and headaches; at present, there is a lack of a nanoemulsion preparation method that can achieve lasting blood microcirculation and local antibacterial effects

Method used

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  • Preparation method and application of supramolecular ginger oil nanoemulsion for promoting microcirculation
  • Preparation method and application of supramolecular ginger oil nanoemulsion for promoting microcirculation
  • Preparation method and application of supramolecular ginger oil nanoemulsion for promoting microcirculation

Examples

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Effect test

Embodiment 1

[0021] The present embodiment provides a preparation method of nanoemulsion for promoting microcirculation, comprising the following steps:

[0022] (1) 200g ginger oil and 50g polysorbate-80 are heated and mixed uniformly, and dissolved completely to form solution A;

[0023] (2) adding 30g 1,2-pentanediol to 1000mL deionized water and stirring to form solution B;

[0024] (3) The solution A is added dropwise to the solution B, and shearing is performed while the dropwise addition is performed, and the colostrum is obtained after the shearing is uniform, and then the colostrum is homogenized by high pressure to obtain a stable nanoemulsion.

[0025] Bacteriostatic results against Candida albicans

[0026]

[0027] The above table is the antibacterial result table of the nanoemulsion prepared in Example 1 against Candida albicans. It can be seen from the table that the antibacterial effect of the nanoemulsion prepared in Example 1 is good.

Embodiment 2

[0029] The present embodiment provides a preparation method of nanoemulsion for promoting microcirculation, comprising the following steps:

[0030] (1) 200g ginger oil is heated and mixed with 50g PEG-40 hydrogenated castor oil, and it is completely dissolved to form solution A;

[0031] (2) adding 30g 1,2-pentanediol to 1000mL deionized water and stirring to form solution B;

[0032] (3) The solution A is added dropwise to the solution B, and shearing is performed while the dropwise addition is performed, and the colostrum is obtained after the shearing is uniform, and then the colostrum is homogenized by high pressure to obtain a stable nanoemulsion.

Embodiment 3

[0034] The present embodiment provides a preparation method of nanoemulsion for promoting microcirculation, comprising the following steps:

[0035] (1) 200g ginger oil and 50g glyceric acid fatty acid esters are heated and mixed, completely dissolved to form solution A;

[0036] (2) adding 30g 1,2-pentanediol to 1000mL deionized water and stirring to form solution B;

[0037] (3) The solution A is added dropwise to the solution B, and shearing is performed while the dropwise addition is performed, and the colostrum is obtained after the shearing is uniform, and then the colostrum is homogenized by high pressure to obtain a stable nanoemulsion.

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PUM

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Abstract

The invention relates to the technical field of nanoemulsion preparation, and discloses a preparation method and application of a supramolecular ginger oil nanoemulsion for promoting microcirculation, and the preparation method of the nanoemulsion comprises the following steps: (1) heating and uniformly mixing ginger oil (with cinnamon, vanillyl butyl ether and the like) and a surfactant, and completely dissolving to form a solution A; (2) adding a water-soluble raw material into a hydrophilic solvent, and stirring to form a solution B; (3) slowly adding the solution A into the solution B, dropwise adding while shearing, uniformly shearing to obtain primary emulsion, and homogenizing the primary emulsion at high pressure to obtain stable nano-emulsion; the ginger oil and other active ingredients are prepared into the nano-emulsion, and then the nano-emulsion is added into the application, so that the effects of persistently promoting blood microcirculation and locally inhibiting bacteria can be achieved.

Description

technical field [0001] The invention relates to a preparation method and application of a supramolecular ginger oil nanoemulsion for promoting microcirculation. Background technique [0002] At present, many people are in a sub-health state due to lack of exercise and physical care, and have sub-health symptoms, such as poor blood circulation, low immunity, poor gastrointestinal function, dizziness, vomiting, poor cardiovascular function, intestinal poor peristalsis, digestive disorders, constipation, dysentery, dizziness and headache; at present, there is a lack of a nanoemulsion preparation method that can achieve lasting promotion of blood microcirculation and local bacteriostatic effect. SUMMARY OF THE INVENTION [0003] The object of the present invention is to: provide a kind of preparation method and application of supermolecular ginger oil nanoemulsion for promoting microcirculation, by making ginger oil into nanoemulsion and applying the paste, then reaching the e...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/107A61K9/70A61K9/00A61P31/02A61P7/00A61P31/10A61K8/92A61K8/06A61Q17/00A61Q11/00A23L33/105
CPCA61K36/9068A61K9/1075A61K9/7023A61K9/0014A61K9/0004A61K9/0053A61P31/02A61P7/00A61P31/10A61K8/922A61K8/068A61Q17/005A61Q11/00A23L33/105A23V2002/00A23V2200/30A23V2250/21Y02A50/30
Inventor 张嘉恒吴称玉吴金金陈石芳周名清许慧娴王振元陈兵洋
Owner SHENZHEN SHINESKY BIOLOGICAL TECH CO LTD
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