The invention discloses an ultrasound knife for an ophthalmologic operation. The ultrasound knife comprises an ultrasound knife instrument, a rotating support is installed at one corner of the top ofthe ultrasound knife instrument, a longitudinal telescopic rod is rotatably arranged on the ultrasound knife instrument through the rotating support, a transverse telescopic supporting rod is fixedlyconnected to the upper end of the longitudinal telescopic rod, a storage device is fixedly arranged at the end, away from the longitudinal telescopic supporting rod, of the transverse telescopic supporting rod and used for storing the head of the ultrasound knife, and a winding mechanism is fixedly arranged on the part, on one side of the storage device, of the telescopic supporting rod, and comprises a round bottom plate, a screw rod and a movable disc. The longitudinal telescopic supporting rod and the transverse telescopic supporting rod are arranged rotatably, in this way, during the operation, a connecting line of the head of the knife and the instrument is wired, the operation is conducted conveniently, meanwhile, the winding device can take up and pay off the wire, the length of thewire is determined according to the operation, during the operation, pulling and falling caused by the wire are voided, the convenience of the operation is improved, and the ultrasound knife is suitable for application and popularization.