Traditional Chinese medicine composition for treating acute lung injury as well as preparation method and application thereof

A technology for acute lung injury and composition, which is applied in the field of traditional Chinese medicine composition and preparation for treating acute lung injury, to achieve obvious therapeutic effects, prevent colonization of pathogenic bacteria, and increase the effect of beneficial bacteria

Active Publication Date: 2022-07-22
SHANXI UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Aiming at the problem of immune lung injury caused by intestinal microbial flora imbalance in rats with intestinal ischemia-reperfusion-induced acute lung injury, the present invention provides a traditional Chinese medicine composition for treating acute lung injury, its preparation method and application

Method used

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  • Traditional Chinese medicine composition for treating acute lung injury as well as preparation method and application thereof
  • Traditional Chinese medicine composition for treating acute lung injury as well as preparation method and application thereof
  • Traditional Chinese medicine composition for treating acute lung injury as well as preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0025] This embodiment provides a traditional Chinese medicine composition, the raw material composition of which is as follows: 10g of raw ephedra, 10g of cohosh, 15g of angelica, 15g of Anemarrhena, 30g of Polygonatum japonica, 15g of Scutellaria baicalensis, 15g of Paeonia lactiflora, 30g of Asparagus, 30g of Artemisia annua, Turtle shell 30g, grass fruit 10g, Magnolia officinalis 15g, gypsum 30g, Atractylodes Rhizoma 30g, licorice 10g.

[0026] The above-mentioned raw materials are pulverized into fine powder, then mixed and soaked for 30 minutes, decocted twice, and the filtrate after the two decoctions is mixed and concentrated to a final concentration of 2 g / mL. The aromatic water preparation is prepared by conventional methods.

Embodiment 2

[0028] Raw Ephedra 14g, Cimicifuga 8g, Angelica 10g, Anemarrhena 20g, Polygonatum 35g, Scutellaria 25g, White Peony 10g, Asparagus 8g, Artemisia annua 26g, Turtle 14g, Caoguo 18g, Magnolia 24g, Raw Gypsum 12g, Atractylodes 22g, licorice 15g.

[0029] The above-mentioned raw materials are pulverized into fine powder, then mixed and soaked for 30 minutes, decocted twice, and the filtrate after the two decoctions is mixed and concentrated to a final concentration of 2 g / mL. Powders are prepared by conventional methods.

Embodiment 3

[0031] Raw Ephedra 18g, Cimicifuga 12g, Angelica 24g, Anemarrhena 14g, Polygonatum 15g, Scutellaria 15g, White Peony 12g, Asparagus 36g, Artemisia annua 26g, Turtle 30g, Caoguo 15g, Magnolia 18g, Raw Gypsum 8g, Atractylodes 8g, licorice 8g.

[0032] The above-mentioned raw materials are pulverized into fine powder, then mixed and soaked for 30 minutes, decocted twice, and the filtrate after the two decoctions is mixed and concentrated to a final concentration of 2 g / mL. An ointment is prepared in a conventional manner.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating acute lung injury and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine compound preparations. The traditional Chinese medicine composition for treating acute lung injury is prepared from the following raw material medicines in parts by weight: 5-20 parts of raw ephedra, 5-20 parts of rhizoma cimicifugae, 5-30 parts of angelica sinensis, 5-30 parts of rhizoma anemarrhenae, 5-40 parts of radix polygonati officinalis, 5-30 parts of scutellaria baicalensis, 5-30 parts of radix paeoniae alba, 5-40 parts of asparagus fern, 5-40 parts of artemisia apiacea, 5-40 parts of turtle shell, 5-20 parts of amomum tsao-ko, 5-30 parts of mangnolia officinalis, 5-50 parts of gypsum, 5-40 parts of rhizoma atractylodis and 5-20 parts of liquorice. According to the invention, the colonization of pathogenic bacteria is prevented by regulating the structural distribution and composition of intestinal flora and up-regulating the immune response of a body. The feed additive can improve the imbalance of intestinal flora, increase beneficial flora capable of generating short-chain fatty acid, inhibit harmful flora and play a positive role in regulating flora. The traditional Chinese medicine composition has an obvious treatment effect on acute lung injury and has a good clinical application prospect.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine compound preparations, in particular to a traditional Chinese medicine composition for treating acute lung injury, a preparation method and an application. Background technique [0002] Acute lung injury (ALI) is a clinical syndrome of acute respiratory failure caused by acute and diffuse inflammatory lung injury caused by various internal and external pathogenic factors. ALI is one of the common respiratory critical illnesses, and its fatality rate is as high as 40% to 50% in the intensive care unit. [0003] The essence of ALI is an uncontrolled inflammatory response, and its pathogenesis has not been fully elucidated. There is still a lack of effective treatment methods. The treatment strategies only reduce the bacterial load and reduce organ damage caused by excessive inflammation, and the mortality rate is still high. At present, all kinds of infectious diseases are show...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9064A61P11/00A61P1/00A61P31/04A61K35/586A61K33/06
CPCA61K36/17A61K36/232A61K36/8964A61K36/8969A61K36/539A61K36/71A61K36/65A61K36/8965A61K36/282A61K35/586A61K36/9064A61K36/575A61K33/06A61K36/284A61K36/484A61P11/00A61P1/00A61P31/04A61K2300/00Y02A50/30
Inventor 彭涛马艳苗樊慧杰张育敏陈富丽宋博刘明燃赵丽君
Owner SHANXI UNIV OF CHINESE MEDICINE
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