37results about How to "Lessen lung damage" patented technology

Methods of treating conditions associated with lipid oxidation or microbial proliferation include the step of administering a composition comprising a pharmacologically effective amount of an antioxidant or antimicrobial lung surfactant protein compound. Peptides derived from lung surfactant protein compounds possess lipid oxidation inhibiting and/or antimicrobial properties.

The invention discloses a Changshanhuyou tangelo and Quzhouhertao peach compound juice drink, and belongs to the technical field of drinks and preparations of the drinks. The drink is prepared by components in parts by weight as follows: 10-12 parts of Changshanhuyou tangelo juice, 20-24 parts of Quzhouhertao peach juice, 5-7 parts of liquorice extracting solutions, 5-7 parts of red autumn sunflower extracting solutions and the balance of water, wherein the total number of parts of the total volume of the drink is 100. The provided compound juice drink has tempting color and sour, sweet and mouthwatering taste, no edible essence and pigment are added, and the original characteristics of raw materials are kept to the greatest extent; and the compound juice drink has the efficacy of decreasing internal heat, replenishing strength and keeping health and is suitable for people of all ages and both sexes.

The present invention relates to inhibitors of C5a for use in the treatment of pneumonia, especially viral pneumonia. The invention also relates to the use of inhibitors of C5a in the preparation of a pharmaceutical composition for the treatment of pneumonia, especially viral pneumonia. The inventors further relates to methods for the treatment of pneumonia, especially viral pneumonia, comprising the step of administering a therapeutic amount of an inhibitor of C5a to a subject in need thereof.

The invention provides a pharmaceutical composition for treating viral infection of respiratory system. The pharmaceutical composition contains chloroquine and a sputum-removing drug. The sputum-removing drug is selected from at least one of acetylcysteine, ambroxol or ammonium chloride. The invention provides a preparation method of the pharmaceutical composition for preventing and treating diseases caused by virus infection of a human respiratory system. The medicine composition of the chloroquine and sputum-removing drug is prepared into a spray, an aerosol or an inhalation preparation forpreventing and treating the diseases caused by the virus infection of the human respiratory system.

The invention discloses an application of a black barley leaven in relieving lung injury and intestinal flora disorder and relates to the technical field of medicines and healthcare products. Lactobacillus plantarum is a fermenting strain used by the leaven. The application of the black barley leaven in relieving lung injury and intestinal flora disorder caused by cooking lampblack has the technical effects of obviously relieving pneumonemia and improving intestinal flora disorder.

The invention concerns the use of a bombesin/gastrin releasing peptide antagonist in the treatment of inflammatory and immune-mediated inflammatory conditions, in particular sepsis, acute lung injury and rheumatoid arthritis as well as for the treatment or prophylaxis of brain disorders, preferably bipolar disorder, and in particular the different forms and/or subforms of bipolar disorder, such as mania, acute mania, severe mania, hypomania, depression, moderate depression, dysthymia, severe depression, episodes of mania and/or depression, psychosis/psychotic symptoms (e.g. hallucinations, delusions), mixed bipolar state, bipolar I disorder, bipolar II disorder and/or rapid-cycling bipolar disorder. In particular, specific nonapeptides with antagonist properties against bombesin or bombesin-like peptides, such as the gastrin releasing peptide, may be used in the treatment of inflammatory and immune-mediated inflammatory conditions as well as brain disorders.

Methods for the reversal of hemorrhagic shock or hemorrhagic trauma.

The invention discloses a preparation method of a polyphyllin nano-liposome dry powder inhalation, which comprises the following steps: preparing liposome by adopting a film dispersion method, a reversed-phase evaporation method or a solvent injection method, and then drying by adopting a spray drying method or a freeze drying method to obtain the polyphyllin nano-liposome dry powder inhalation. The polyphyllin nano-liposome dry powder inhalation prepared by the invention has the advantages that the production conditions are easy to control, the particle size distribution of prepared particles is relatively concentrated, the stability, the flowability and the dispersity are good, the potential is 25-32mV, and the medicine can be slowly released within 16-24h. The polyphyllin nano-liposome dry powder inhalation can be used for preparing a medicine for preventing or treating 2019-nCoV(nCoV).

The present disclosure provides the use of mesenchymal stem cells (MSC) in the treatment of viral infection and/or complications caused by the viral infection. MSC can highly express multiple antioxidative stress genes and secrete multiple antioxidative stress factors under the stimulation of oxidative stress, inhibit inflammatory reaction and excessive activation of immune cells, thus improving inflammatory indexes and myocardial injury indexes of human bodies. MSC can regulate the expression profile of monocyte genes and monocyte toxicity genes in patients with viral infection, inhibit the excessive immune response, protect alveolar function, and reduce the damage of lung and whole body organs in patients with viral infection. MSC can regulate the expression of antivirus-related genes and coagulation-related genes of terminally differentiated cell subsets in patients with viral infection, inhibit the excessive activation of monocytes in patients with viral infection, and effectively treat the complications of patients with viral infection.

Systems and methods for gas exchange in a patient are provided that use an external circuit to cause oxygenation perfusion in a patient's body cavity (such as the abdomen) using an inert chemical (e.g., perfluorocarbon), independent of the lungs. The external circuit includes components configured to control properties of the chemical, including temperature, flow rate, pressure, oxygenation percentage, carbon dioxide percentage. The system also includes safety features to reduce the likelihood of injury to the patient. Each of the safety features and chemical properties can be controlled by a healthcare worker, such as a physician, nurse, or emergency operator, for a particular patient.

The invention discloses a cochliobolus quinone B derivative, a production strain and applications. The structural formula of the derivative is shown as the description. The derivative is produced by aBipolaris sorokiniana KLBMPSM007 obtained through separating and screening; and the Bipolaris sorokiniana KLBMPSM007 has been deposited in a common microorganism center of the China committee for culture collection of microorganisms, the deposited time is on 5th June, 2017, and the deposited number is CGMCC NO. 13900. The compound can significantly increase the survival rates of mice infected bypseudomonas aeruginosa, reduce lung injury and bacterial diffusion, and show good biological effects of against pseudomonas aeruginosa infection; and the occurrence of autophagy of alveolar macrophagecan be directly induced through compound processing, so that the macrophage can be promoted to perform identification, phagocytosis and degradation on the pseudomonas aeruginosa, and the invading ofthe pseudomonas aeruginosa can be resisted.

The invention relates to a traditional Chinese medicine composition for preventing and treating lung injury due to radioactive radon and daughters thereof, that is a radon lung injury protective agent, and particularly is to develop a radon lung injury protective agent which can prevent and treat pneumonia, pulmonary fibrosis, and lung cancer caused by high radon exposure. The invention comprises traditional Chinese medicines which can tonify qi and nourish yin, clear heat and invigorate blood, strengthen body resistance and remove toxin, can reduce lung injury caused by high radon exposure, can be used for the prevention and treatment of pneumonia, pulmonary fibrosis, and lung cancer caused by radioactive radon and daughters thereof.

The invention discloses an application of FUNDC1 in treating acute respiratory distress syndrome and belongs to the technical field of biology. The present invention provides the application of the FUNDC1 in preparing products for preventing and/or treating inflammatory diseases. The mechanism of the FUNDC1 in preventing and/or treating inflammatory diseases is mainly to reduce lung injury by mediating mitochondrial autophagy to inhibit activation and expansion of inflammatory reactions induced by an ROS-NLRP3 signaling pathway. The invention provides the application of the FUNDC1 in preparingproduct for preventing and/or treating acute respiratory distress syndrome. The product provided by the invention can reduce lung injury by inhibiting inflammatory reactions by promoting autophagy during ARDS period. The FUNDC1 is expected to become a new target for ARDS treatment and has a wide application prospect.

The invention discloses a traditional Chinese medicine composition for treating acute lung injury and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine compound preparations. The traditional Chinese medicine composition for treating acute lung injury is prepared from the following raw material medicines in parts by weight: 5-20 parts of raw ephedra, 5-20 parts of rhizoma cimicifugae, 5-30 parts of angelica sinensis, 5-30 parts of rhizoma anemarrhenae, 5-40 parts of radix polygonati officinalis, 5-30 parts of scutellaria baicalensis, 5-30 parts of radix paeoniae alba, 5-40 parts of asparagus fern, 5-40 parts of artemisia apiacea, 5-40 parts of turtle shell, 5-20 parts of amomum tsao-ko, 5-30 parts of mangnolia officinalis, 5-50 parts of gypsum, 5-40 parts of rhizoma atractylodis and 5-20 parts of liquorice. According to the invention, the colonization of pathogenic bacteria is prevented by regulating the structural distribution and composition of intestinal flora and up-regulating the immune response of a body. The feed additive can improve the imbalance of intestinal flora, increase beneficial flora capable of generating short-chain fatty acid, inhibit harmful flora and play a positive role in regulating flora. The traditional Chinese medicine composition has an obvious treatment effect on acute lung injury and has a good clinical application prospect.

The invention provides application of kaempferol 3-glucorhamnoside in preparation of a medicine for treating systemic severe sepsis, and belongs to the technical field of biological medicines. The inventor of the invention finds that the kaempferol 3-glucorhamnoside can improve and treat the severe sepsis by reducing TNF-alpha, IL-6 increase and IL-10 decrease caused by severe sepsis in serum, reducing TNF-alpha, IL-6 increase and IL-10 decrease caused by severe sepsis in the liver, reducing TNF-alpha, IL-6 increase and IL-10 decrease caused by severe sepsis in the lung, and reducing TNF-alpha, IL-6 increase and IL-10 decrease caused by severe sepsis in the spleen. Secondly, the kaempferol 3-glucorhamnoside can improve and treat the severe sepsis by reducing lung injury caused by the severe sepsis and inhibiting increase of phosphorylation degree of ERK1/2, JNK and p38 and increase of phosphorylation degree of I kappa B and NF-kappa B caused by severe sepsis. Therefore, the kaempferol3-glucorhamnoside can be used for preparing a potential medicine for treating diseases related to the systemic severe sepsis.