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Application of black barley leaven in relieving lung injury and intestinal flora disorder

A technology of intestinal flora and barley fermentation, which is applied in the field of medicine and health care products, can improve the disorder of intestinal flora, alleviate the condition of pulmonary congestion, and have a good application prospect

Active Publication Date: 2019-08-02
SHANGHAI JIAO TONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] In view of the above-mentioned defects of the prior art, the technical problem to be solved by the present invention is how to use the fermented product of black barley to provide a new application: a fermented product of black barley Application in prevention and correction of lung injury and intestinal flora disorder caused by cooking fumes and air pollution

Method used

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  • Application of black barley leaven in relieving lung injury and intestinal flora disorder
  • Application of black barley leaven in relieving lung injury and intestinal flora disorder
  • Application of black barley leaven in relieving lung injury and intestinal flora disorder

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Preparation of fermented Lactobacillus black barley:

[0037] Crush the black barley and pass it through an 80-mesh sieve, add pure water according to the ratio of material to liquid of 1:5 (m / m), stir and heat up to 65°C; add α-high temperature amylase (10U / g) for enzymatic hydrolysis for 40 minutes; saccharification The finished black barley medium is put into an autoclave for sterilization, and after cooling, add the activated Lactobacillus plantarum bacterium liquid (containing 109 CFU / ml of viable bacteria) in the cooled black barley medium by an inoculum size of 3%. ), fermented at 30°C for 24h, and fermented on a shaking table (100rpm).

[0038] The fermented product of Lactobacillus black barley and its fermented strains are used as a health product (functional food) to alleviate lung injury and intestinal flora disorder caused by cooking fumes and air pollution. The following are the main pharmacodynamic tests:

[0039] 1. In vitro antioxidant activity analysi...

Embodiment 2

[0062] On the basis of Example 1, the Lactobacillus black fermented product obtained by fermentation is further made into a Lactobacillus black fermented food, a Lactobacillus fermented beverage, and the fermented product of Lactobacillus black is dried and processed by freeze-drying or spray drying The obtained solid powder functional food.

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Abstract

The invention discloses an application of a black barley leaven in relieving lung injury and intestinal flora disorder and relates to the technical field of medicines and healthcare products. Lactobacillus plantarum is a fermenting strain used by the leaven. The application of the black barley leaven in relieving lung injury and intestinal flora disorder caused by cooking lampblack has the technical effects of obviously relieving pneumonemia and improving intestinal flora disorder.

Description

technical field [0001] The invention relates to the technical field of medicine and health care products, in particular to the application of a black barley fermented product in reducing lung injury and intestinal flora disorder caused by cooking fume. Background technique [0002] Lung cancer is an important global public health problem characterized by delayed diagnosis, early metastasis, high mortality and low survival. Cooking fumes are one of the most common sources of indoor air pollution, and cooking-induced indoor air pollution (IAP) has been associated with lung cancer risk in a retrospective case-control study in developing and rural countries. In recent years, cooking fume exposure has been shown to be one of the pathogenic factors of lung cancer (Barko P C, Mcmichael M A, Swanson K S, et al. The Gastrointestinal Microbiome: A Review [J]. Journal of Veterinary Internal Medicine, 2018, 32(1) :9-25; Beamish L A, Osornio-Vargas AR, Wine E. Air pollution: An environm...

Claims

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Application Information

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IPC IPC(8): C12P1/04A61K36/8998A61P11/00A61P1/00A23L7/104A23L33/00A23L2/38A21D13/06C12R1/25
CPCC12P1/04A61K36/8998A61P11/00A61P1/00A23L7/104A23L33/00A23L2/382A21D13/06A23V2002/00C12R2001/25C12N1/205A23V2400/169A23V2200/314A23V2200/32
Inventor 宋立华丁信文管玘杨丽曾辉吴佳怡宋晨玮
Owner SHANGHAI JIAO TONG UNIV
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