Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Medicinal composition for treating psoriasis

A composition and technology for psoriasis, which can be applied in drug combinations, skin diseases, pharmaceutical formulations, etc., and can solve problems that have not been reported yet

Inactive Publication Date: 2005-07-13
CHONGQING HUAPONT PHARMA
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After retrieval, so far this compound preparation has no report in the existing literature

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Example 1 Compound Tazarotene Betamethasone Dipropionate Cream

[0015] Element:

[0016] Tazarotene 0.05g

[0017] Betamethasone Dipropionate 0.064g

[0018] Liquid paraffin 28g

[0019] Vaseline 10g

[0020] Cetyl Alcohol 4g

[0021] Octadecanol 1.5g

[0022] Glyceryl monostearate 7g

[0023] Ping Ping O 20 0.6g

[0024] Span-60 6g

[0025] Propylene glycol 5g

[0026] Benzyl alcohol 1g

[0027] Distilled water up to 100g

Embodiment 2

[0028] Example 2 Compound Tazarotene Betamethasone Dipropionate Cream

[0029] Element:

[0030] Tazarotene 0.1g

[0031] Betamethasone Dipropionate 0.064g

[0032] Liquid paraffin 33g

[0033] Beeswax 8g

[0034] Isopropyl Palmitate 6g

[0035] Span-60 8.4g

[0036] Tween-80 1.6g

[0037] Propylene glycol 5g

[0038] Benzyl alcohol 1g

[0039] Potassium sorbate 0.05g

[0040] Distilled water up to 100g

Embodiment 3

[0041] Example 3 Compound Tazarotene Fluticasone Propionate Cream

[0042] Element:

[0043] Tazarotene 0.05g

[0044] Fluticasone Propionate 0.05g

[0045] Silicone oil 30g

[0046] Vaseline 8g

[0047] Cetyl Alcohol 6g

[0048] Glyceryl monostearate 6.5g

[0049] Ping Ping O 20 0.55g

[0050] Span-60 3.8g

[0051] Propylene glycol 4.5g

[0052] Benzyl alcohol 1g

[0053] Distilled water up to 100g

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a pharmaceutical composition for treating psoriasis, and its preparation forms include ointment and gel. The pharmaceutical composition contains 0.05%-0.5% (w / w) of tazarotene, 0.05%-2.5% (w / w) of adrenocorticosteroids and other pharmaceutically acceptable auxiliary agents. The adrenocortical hormone drug is preferably betamethasone dipropionate. The pharmaceutical composition of the invention has remarkable curative effect on psoriasis and good safety.

Description

Technical field: [0001] The invention relates to a pharmaceutical composition for treating psoriasis, in particular to an ointment and a gel containing tazarotene and adrenocortical hormone drugs. Background technique: [0002] Tazarotene and adrenal corticosteroids are commonly used in the clinical treatment of dyskeratotic skin diseases. Tazarotene can cut off the three pathological processes of such skin diseases: ① hyperplasia of keratinocytes in the basal layer; ② parakeratosis; ③ inflammatory response of the epidermis; In the early stage of inflammation, it can reduce exudation, edema, telangiectasia, leukocyte infiltration and phagocytosis, thereby improving symptoms such as redness, swelling, heat, and pain. In the later stage, it can inhibit the proliferation of capillaries and fibroblasts, continue the formation of granulation tissue, and prevent scarring Formation, reduce inflammation, corticosteroids and tazarotene combined treatment of psoriasis can shorten the...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/4436A61K31/56A61K31/573A61K31/58A61P17/06
Inventor 魏向阳朱学琳王永军张颖李娟
Owner CHONGQING HUAPONT PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com