Prepration process for biologic hemostatic sponge material

Abstract

A method of producing biological hemostasis spongy material. It comprises: taking chitosan / chitin as the main raw material, preparing the solution, defoaming and putting into a container and freeze-drying, forming a spongy layer with the thickness of 1-10mm; soaking with ammonia, ammonia / alcohol, ammonia / acetone, ammonia / methanol, washing with distilled water, freeze-drying and disinfecting. The prepared hemostasis spongy material has abilities of stanching bleeding and promoting tissue rehabilitation.

Description

technical field

[0001] The invention relates to a preparation method of a medical biological hemostatic material, which belongs to the technical field of medical material preparation. Background technique

[0002] Chitin, also known as chitosan, chitin, chitin, chitin, shell protein, etc., is a linear amino polysaccharide that maintains and protects the bodies of crustaceans and microorganisms and is insoluble in water, alkali and conventional solvents. Widely present in the wings or shells of arthropods (spiders, crustaceans) and in the cell walls of fungi and algae (Chen Tian, ​​Yan Jun, Xu Rongnan, Xia Yan. Journal of Biomedical Engineering, 1989; 6 (1) : 60.), the annual biosynthesis is nearly one billion tons, only 10% to 30% of the crustacean waste after the processing of aquatic products such as crabs and shrimps. It is a natural resource with potential value and yet to be developed. Acid-soluble chitosan (Chitosan) is a deacetylated compound of chitin, a derivative...