Dermatopathy therapeutic medicine compositions and its preparation method

A composition and technology for skin diseases, applied in the directions of drug combination, skin diseases, drug delivery, etc., can solve problems such as skin fungal infection, dermatitis or eczema that cannot be effectively treated, and achieve strong antifungal effect and good curative effect.

Inactive Publication Date: 2006-08-30
YAKEXI PHARMA INST BEIJING
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The object of the present invention is to provide a kind of pharmaceutical composition for the treatment of skin disease and preparation method thereof, especially provide a kind of allylamine antifungal drug and adrenal cortex hormone pharmaceutical composition and preparation method thereof, overcome above-mentioned single component cannot Effective treatment of skin fungal infection, dermatitis or eczema, and the disadvantages of simultaneous disease of fungal infection, dermatitis and eczema

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0082] Medicinal ointment of the present invention

[0083] Weigh 1.0 g of terbinafine hydrochloride, 0.1 g of triamcinolone acetonide, and 0.5 g of preservative chlorhexidine acetate according to a formula ratio of 1.0:0.1, dissolve them with a small amount of ethanol, and use an O / W dosage form. 4 grams of octal alcohol, 4 grams of stearic acid, 3.5 grams of glyceryl monostearate, 10 grams of petrolatum, 10 grams of glycerin, 2 grams of Tween-80 and the remainder of distilled water are prepared into 100 grams of ointment.

Embodiment 2

[0085] Medicinal cream of the present invention

[0086] Weigh 1.5 grams of terbinafine hydrochloride and 0.05 grams of betamethasone according to the formula ratio of 0.5:0.05, dissolve them with a small amount of ethanol, and use O / W dosage form. The excipients are 4 grams of stearyl alcohol, 10 grams of stearic acid, 5 grams of glyceryl monostearate, 6 grams of vaseline, 10 grams of glycerin, 0.8 grams of triethanolamine and the remainder of distilled water are mixed with 100 grams of cream.

Embodiment 3

[0088] Medicinal solution of the present invention

[0089] Take by weighing 0.5 grams of terbinafine hydrochloride and 0.5 grams of clonazepam according to the formula ratio of 0.5:0.08, add 20 ml of ethanol, 20 ml of propylene glycol, and the remainder of distilled water to prepare 100 ml of a solution.

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Abstract

The invention relates to a dermatopathy therapeutic medicine compositions and its preparation method, in particular a propylene amine antimycotics, and suprarenal hormones medicinal compositions and its preparation method.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating skin diseases and a preparation method thereof, in particular to an allylamine antifungal drug and adrenocortical hormone pharmaceutical composition and a preparation method thereof. Background technique [0002] Terbinafine hydrochloride (abbreviated as Terbinafine, Terbinafine) is an allylamine antifungal drug, which is characterized in that it has a higher fungicidal cure rate and a lower recurrence rate in a short period of time, but some skin mycosis It is often indistinguishable from dermatitis and eczema, causing misdiagnosis. Triamcinolone acetonide acetate (Triamcinoloni for short), Betamethasone (Betamethasone) and Halcincnide (Halcincnide) are adrenal cortex hormone drugs, which have anti-inflammatory effects and no fungicidal effect. The above-mentioned single components It has the disadvantage of not being able to effectively treat skin fungal infection, dermatitis or ecze...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/58A61K9/00A61P17/00A61P31/10A61K31/137
Inventor 周红黄家章
Owner YAKEXI PHARMA INST BEIJING
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