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Medicine for treating chronic pain, and its prepn. method

A technology for chronic pain and traditional Chinese medicine, applied in the field of traditional Chinese medicine, can solve the problems of non-compliance with drug testing standards, inaccessible traditional Chinese medicine, mixed chemical components, etc., achieving clear pharmacology and efficacy, clear drug toxicology, and high industrialization maturity. Effect

Inactive Publication Date: 2003-12-03
LANGDUO SCI & TECH DEV BEIJING
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, traditional Chinese medicine preparations exported abroad include pills such as "Wuji Baifeng Pills" and "Liuwei Dihuang Pills"; Traditional Chinese medicine is decocted and concentrated, with mixed chemical components and dark color. It does not meet the drug inspection standards set by foreign drug inspection departments. The pharmacological mechanism cannot be explained by modern scientific theories. Even in foreign countries, it is mainly sold to a small number of Chinese groups. The current state is simply unable to enter the mainstream foreign pharmaceutical market

Method used

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  • Medicine for treating chronic pain, and its prepn. method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] 1. Asarum 1 kg is crushed into 2-4 mm sized particles.

[0037] Soak in 2.5 liters of 60% ethanol and boil until slightly boiled for 4 hours, filter the solution to collect the filter residue.

[0038] 3. Boil the filter residue with 15 times of water for 4 hours, collect the solution and discard the residue, repeat the extraction once, centrifuge and combine the extract.

[0039] 4. Add 95% ethanol to the extract until the ethanol concentration reaches 80%, and let stand overnight at 4°C.

[0040] 5. Centrifuge, wash the precipitate twice with ethanol, and dry under low pressure to obtain powdered asarum polysaccharide extract.

[0041] The raw materials Asarum, Panax notoginseng, American ginseng, white fungus, Codonopsis pilosula or lacquer listed in claim 1 can refer to this method to extract polysaccharides. The asarum, notoginseng and white fungus polysaccharide extracts equivalent to 1 g of the crude drugs were combined, dissolved in 20 ml of water to prepare a...

Embodiment 2

[0043] 1. Take 1 kg of Codonopsis pilosula slices, boil them with 5 times the volume of 60% ethanol until slightly boiled for 4 hours, filter the solution and collect the filter residue.

[0044] 2. Boil the filter residue with 15 times of water for 4 hours, collect the extract, and repeat the extraction twice. The extracts were combined after ultrafiltration.

[0045] 3. Concentrate the extract under reduced pressure to 1 liter.

[0046] 4. Add 4 volumes of 95% ethanol to mix well, and let it stand overnight at 4°C.

[0047] 5. The filter residue obtained by ultrafiltration is washed twice with ethanol

[0048] 6. The filter residue is dissolved in water and then spray-dried to obtain a powdery Codonopsis polysaccharide extract.

[0049] The raw materials Asarum, Panax notoginseng, American ginseng, white fungus, Codonopsis pilosula or lacquer listed in claim 1 can refer to this method to extract polysaccharides. Take Codonopsis pilosula, Codonopsis lacquer, American gins...

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Abstract

A Chinese medicine in the form of oral liquid for treating the chronic pain caused by the peripheroneural damage is prepared from 5 Chinese medicinal materials including asarum herb, notoginseng, American ginseng, tremella, and pilose asiabell root on achyranthes bidentate through extracting polyose substances separately. The extracted polyose components have the function of repairing the nerve ending causing the chronic pain and contain no inhibitor on the nervous centralis. Its advantages are high curative effect, quickly taking its effect and no toxic by-effect.

Description

technical field [0001] The invention belongs to the pharmaceutical category of traditional Chinese medicine in the field of biomedicine. technical background [0002] China has a history of thousands of years of civilization, which is also the history of the development of the theory and application of traditional Chinese medicine. China has a vast territory and rich plant resources, and Chinese medicine should make greater contributions to the world. However, because the theory and preparation methods of Chinese medicine are difficult to be recognized by the West, 95% of the world's herbal medicine market is dominated by refined processing in Japan and Japan. South Korea occupies, China only occupies less than 5%, and it is still dominated by raw materials and rough processed products, and the added value of products is low. After China's accession to the World Trade Organization (WTO), major pharmaceutical manufacturers from various countri...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61P29/00
Inventor 谢益宽韩苏李无忌
Owner LANGDUO SCI & TECH DEV BEIJING
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