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Medicine for treating diabetes and its complication

A technology for complications and diabetes, applied in the field of diabetes, can solve problems such as accelerated consumption of insulin

Inactive Publication Date: 2004-06-23
上海倍艺医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The mechanism of action of oral antidiabetic drugs in the prior art (such as commonly used sulfonylureas) is mainly based on increasing the release of insulin from the β cells of the pancreas, which may lead to accelerated consumption of endogenously produced insulin in diabetic patients in the long run, The modern view of the pathobiochemistry of diabetes onset in adulthood thus emphasizes the need to treat peripheral insulin resistance in this setting

Method used

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Examples

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Embodiment Construction

[0007] A medicine for treating diabetes and its complications according to the present invention, wherein 1 kg of the medicine contains 0.1 to 1000 mg of phytanic acid or its derivatives, preferably 0.1 to 500 mg of phytanic acid or its derivatives, The balance is that the carrier in the prior art may include diluents, excipients, granulating agents, fillers, disintegrants, wetting agents, lubricants, fragrances, color developers or other conventional agents, the Some include inert diluents such as calcium carbonate, sodium carbonate, lactose, calcium phosphate. Or sodium phosphate, described and disintegrating agent, such as cornstarch or alginic acid: binding agent such as starch, gelatin or gum arabic; And lubricant such as stearate money, stearic acid or talc, the present invention makes Tablets may be uncoated or may be coated by known techniques in order to delay disintegration and absorption in the gastrointestinal tract and thus provide sustained release over a longer ...

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PUM

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Abstract

The medicine for treating diabetes and its complication is compounded with phytanic acid or its derivative, pharmaceutically acceptable additive and / or assistant. The derivative may be alkali metal salt or alkali earth metal salts of phytanic acid or their pharmaceutically acceptable solution. Experiment shows that phytanic acid and its derivative have the activity of raising the taking of liver glucose and eliminating serum glucose and the activity is expressed by gene in enzyme inducing or stimulating insulin secretion. The present invention has excellent curative effect on diabetes, especially diabetes companied with hyperlipidemia, hypercholesterolemia, hypertension, obesity and hyperinsulinemia.

Description

Technical field: [0001] The invention relates to the field of diabetes, in particular to phytanic acid, specifically a medicine for treating diabetes and its complications. Background technique: [0002] Diabetes is the most common metabolic disorder in humans. It is divided into insulin-dependent diabetes and insulin-independent diabetes. Both types of diabetes will damage the body's ability to use glucose as energy. Chronic high blood sugar will slowly damage many tissues and organs of the body. organ. Although insulin can be used to treat diabetes, diabetes remains a serious disease responsible for much death and morbidity worldwide. The consequences of long-term diabetes can include eye damage, often leading to blindness, circulatory problems, wound healing problems, and other serious consequences. Non-insulin-dependent diabetes mellitus is a form of diabetes that occurs primarily in adults who have an adequate supply of insulin but have deficits in insulin-mediated gl...

Claims

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Application Information

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IPC IPC(8): A61K31/66A61P3/10
Inventor 周鼎城
Owner 上海倍艺医药科技有限公司
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