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Use of phytanic acid for treating diabetes

A technology of diabetes and phytanic acid, applied in the field of diabetes, can solve the problems of high toxicity and side effects, accelerated consumption of insulin, and dare not use it, and achieve good results

Inactive Publication Date: 2004-06-30
上海倍艺医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Aminoguanidine is a commonly used drug for the treatment of diabetes, but due to its high toxicity and side effects, people are afraid to use it
[0003] The mechanism of action of oral antidiabetic drugs in the prior art (such as commonly used sulfonylureas) is mainly based on increasing the release of insulin from the β cells of the pancreas, which may lead to accelerated consumption of endogenously produced insulin in diabetic patients in the long run, The modern view of the pathobiochemistry of diabetes onset in adulthood thus emphasizes the need to treat peripheral insulin resistance in this setting

Method used

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Examples

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Effect test

Embodiment Construction

[0007] A kind of medicine for treating diabetes of the present invention, in described 1kg medicine, contain the phytanic acid or its derivative of 0.1 to 1000mg, preferably the phytanic acid or its derivative of the amount of 0.1 to 500mg, the balance is already Carriers in the art may include diluents, excipients, granulating agents, fillers, disintegrants, wetting agents, lubricants, fragrances, color developers or other conventional agents, including inert diluents Agents such as calcium carbonate, sodium carbonate, lactose, calcium phosphate. Or sodium phosphate, and disintegrants such as cornstarch or alginic acid: binders such as starch, gelatin or acacia; and lubricants such as stearic acid Alcohol, stearic acid or talc, the tablets made according to the invention may be uncoated or may be coated by known techniques in order to delay disintegration and absorption in the gastrointestinal tract and thus provide sustained relief over a longer period of time. release effec...

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Abstract

The present invention relates to an application of phytanic acid for curing diabetes. Said invented medicine is prepared by adopting phytanic acid or its derivative and pharmaceutically-acceptable additive and / or adjuvant. The described derivative includes salts with alkali metal and alkali earth metal or their pharmaceutically-acceptable solvent compound. The tests show that said invented medicine has good therapeutic effect for diabetic, specially, for patient with hyperglycemia, hyperlipemia and hypertension.

Description

Technical field: [0001] The invention relates to the field of diabetes, in particular to phytanic acid, specifically the application of phytanic acid in treating diabetes. Background technique: [0002] Diabetes is a serious health killer encountered by humans at present. The symptoms of diabetes include hyperglycemia, incomplete carbohydrate metabolism, glycosuria and decreased insulin sensitivity. If these symptoms are not treated, they often cause serious complications. In the prior art, the commonly used western medicines for controlling type II diabetes are divided into two categories: biguanides and sulfonylureas. Biguanides can prevent excessive hepatic gluconeogenesis, and sulfonylureas mainly stimulate insulin secretion by stimulating insulin secretion. Improve insulin action in certain targeted tissues and lower blood sugar by inhibiting liver sugar synthesis. The basic idea of ​​traditional Chinese medicine treatment of diabetes is to nourish yin, replenish qi, pr...

Claims

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Application Information

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IPC IPC(8): A61K31/66A61P3/10
Inventor 周鼎城
Owner 上海倍艺医药科技有限公司
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